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Volumn 64, Issue 8, 2002, Pages 1233-1242

Potentiation of 1,25-dihydroxyvitamin D3-induced differentiation of human promyelocytic leukemia cells into monocytes by costunolide, a germacranolide sesquiterpene lactone

Author keywords

1,25 Dihydroxyvitamin D3; Cell differentiation; Costunolide; Extracellular signal regulated kinase; Nuclear factor B; Protein kinase C

Indexed keywords

CALCITRIOL; COSTUNOLIDE; GERMACRANOLIDE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; PROTEIN 13K; PROTEIN KINASE C; UNCLASSIFIED DRUG;

EID: 0037107596     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01292-3     Document Type: Article
Times cited : (43)

References (52)
  • 1
    • 0027359202 scopus 로고
    • Differentiation: A suitable strategy for cancer chemotherapy?
    • Beere H.M., Hickman J.A. Differentiation: a suitable strategy for cancer chemotherapy? Anti-Cancer Drug Design. 8:1993;299-322.
    • (1993) Anti-Cancer Drug Design , vol.8 , pp. 299-322
    • Beere, H.M.1    Hickman, J.A.2
  • 2
    • 0001679798 scopus 로고
    • Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid
    • Breitman T.R., Selonick S.E., Collins S.J. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc. Natl. Acad. Sci. USA. 77:1980;2936-2940.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 2936-2940
    • Breitman, T.R.1    Selonick, S.E.2    Collins, S.J.3
  • 3
    • 0021053521 scopus 로고
    • 3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocytic macrophage, but not into granulocytes
    • 3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocytic macrophage, but not into granulocytes. Biochem. Biophys. Res. Commun. 117:1983;86-92.
    • (1983) Biochem. Biophys. Res. Commun. , vol.117 , pp. 86-92
    • Tanaka, H.1    Abe, E.2    Miyaura, C.3    Shiina, Y.4    Suda, T.5
  • 5
    • 0035062018 scopus 로고    scopus 로고
    • Evidence that activation of MEK 1,2/erk 1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells
    • Marcinkowska E. Evidence that activation of MEK 1,2/erk 1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells. Anticancer Res. 21(1A):2001;499-504.
    • (2001) Anticancer Res. , vol.21 , Issue.1A , pp. 499-504
    • Marcinkowska, E.1
  • 6
    • 0031761175 scopus 로고    scopus 로고
    • Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
    • Marcinkowska E., Wiedlocha A., Radzikowski C. Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol. Anticancer Res. 18:1998;3507-3514.
    • (1998) Anticancer Res. , vol.18 , pp. 3507-3514
    • Marcinkowska, E.1    Wiedlocha, A.2    Radzikowski, C.3
  • 7
    • 0033233467 scopus 로고    scopus 로고
    • 3-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex
    • 3-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex. J. Exp. Med. 190:1999;1583-1594.
    • (1999) J. Exp. Med. , vol.190 , pp. 1583-1594
    • Zakaria, H.1    Devki, N.2    Laura, S.3    Keith, L.K.4    Patricia, H.V.5    Neil, E.6
  • 10
    • 0028038184 scopus 로고
    • Chemopreventive effect of costunolide, a constituent of oriental medicine, on azoxymethane-induced intestinal carcinogenesis in rats
    • Mori H., Kawamori T., Tanaka T., Ohnishi M., Yamahara J. Chemopreventive effect of costunolide, a constituent of oriental medicine, on azoxymethane-induced intestinal carcinogenesis in rats. Cancer Lett. 83:1994;171-175.
    • (1994) Cancer Lett. , vol.83 , pp. 171-175
    • Mori, H.1    Kawamori, T.2    Tanaka, T.3    Ohnishi, M.4    Yamahara, J.5
  • 11
    • 0028931506 scopus 로고
    • Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats
    • Kawamori T., Tanaka T., Hara A., Yamahara J., Mori H. Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. Cancer Res. 55:1995;1277-1282.
    • (1995) Cancer Res. , vol.55 , pp. 1277-1282
    • Kawamori, T.1    Tanaka, T.2    Hara, A.3    Yamahara, J.4    Mori, H.5
  • 12
    • 0030934450 scopus 로고    scopus 로고
    • Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis
    • Ohnishi M., Yoshimi N., Kawamori T., Ino N., Hirose Y., Tanaka T., Yamahara J., Miyata H., Mori H. Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis. Jpn. J. Cancer Res. 88:1997;111-119.
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 111-119
    • Ohnishi, M.1    Yoshimi, N.2    Kawamori, T.3    Ino, N.4    Hirose, Y.5    Tanaka, T.6    Yamahara, J.7    Miyata, H.8    Mori, H.9
  • 13
    • 0033571108 scopus 로고    scopus 로고
    • The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
    • Hehner S.P., Hofmann T.G., Droge W., Schmitz M.L. The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex. J. Immunol. 163:1999;5617-5623.
    • (1999) J. Immunol. , vol.163 , pp. 5617-5623
    • Hehner, S.P.1    Hofmann, T.G.2    Droge, W.3    Schmitz, M.L.4
  • 14
    • 0023918670 scopus 로고
    • Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones
    • Hall I.H., Williams W.L. Jr., Grippo A.A., Lee K.H., Holbrook D.J., Chaney S.G. Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones. Anticancer Res. 8:1988;33-42.
    • (1988) Anticancer Res. , vol.8 , pp. 33-42
    • Hall, I.H.1    Williams W.L., Jr.2    Grippo, A.A.3    Lee, K.H.4    Holbrook, D.J.5    Chaney, S.G.6
  • 15
    • 0032990502 scopus 로고    scopus 로고
    • Low concentrations of the feverfew component parthenolide inhibit in vitro growth of tumor lines in a cytostatic fashion
    • Ross J.J., Arnason J.T., Birnboim H.C. Low concentrations of the feverfew component parthenolide inhibit in vitro growth of tumor lines in a cytostatic fashion. Planta Med. 65:1999;126-129.
    • (1999) Planta Med. , vol.65 , pp. 126-129
    • Ross, J.J.1    Arnason, J.T.2    Birnboim, H.C.3
  • 16
    • 0035080282 scopus 로고    scopus 로고
    • Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release
    • Lee M.G., Lee K.T., Chi S.G., Park J.H. Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release. Biol. Pharm. Bull. 24:2001;303-306.
    • (2001) Biol. Pharm. Bull , vol.24 , pp. 303-306
    • Lee, M.G.1    Lee, K.T.2    Chi, S.G.3    Park, J.H.4
  • 17
    • 0018183376 scopus 로고
    • Isolation and characterization of the sesquiterpene lactones costunolide, parthenolide, costunolide diepoxide, santamarine, and reynosin from Magnolia grandiflora L
    • el-Feraly F.S., Chan Y.M. Isolation and characterization of the sesquiterpene lactones costunolide, parthenolide, costunolide diepoxide, santamarine, and reynosin from Magnolia grandiflora L. J. Pharm. Sci. 67:1978;347-350.
    • (1978) J. Pharm. Sci. , vol.67 , pp. 347-350
    • El-Feraly, F.S.1    Chan, Y.M.2
  • 18
    • 0034961142 scopus 로고    scopus 로고
    • Costunolide, a sesquiterpene from the stem bark of Magnolia sieboldii, inhibits the RAS-farnesyl-protein transferase
    • Park S.H., Choi S.U., Lee C.O., Yoo S.E., Yoon S.K., Kim Y.K., Ryu S.Y. Costunolide, a sesquiterpene from the stem bark of Magnolia sieboldii, inhibits the RAS-farnesyl-protein transferase. Planta Med. 67:2001;358-359.
    • (2001) Planta Med. , vol.67 , pp. 358-359
    • Park, S.H.1    Choi, S.U.2    Lee, C.O.3    Yoo, S.E.4    Yoon, S.K.5    Kim, Y.K.6    Ryu, S.Y.7
  • 19
    • 0030445832 scopus 로고    scopus 로고
    • Syringin 4-O-β-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii
    • Park H.J., Jung W.T., Basnet P., Kadota S., Namba T. Syringin 4-O-β-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii. J. Nat. Prod. 59:1996;1128-1130.
    • (1996) J. Nat. Prod. , vol.59 , pp. 1128-1130
    • Park, H.J.1    Jung, W.T.2    Basnet, P.3    Kadota, S.4    Namba, T.5
  • 20
    • 0033760941 scopus 로고    scopus 로고
    • Inhibition of the transcription factor NF-κB by sesquiterpene lactones from Podachaenium eminens
    • Castro V., Murillo R., Klaas C.A., Meunier C., Mora G., Pahl H.L., Merfort I. Inhibition of the transcription factor NF-κB by sesquiterpene lactones from Podachaenium eminens. Planta Med. 66:2000;591-595.
    • (2000) Planta Med. , vol.66 , pp. 591-595
    • Castro, V.1    Murillo, R.2    Klaas, C.A.3    Meunier, C.4    Mora, G.5    Pahl, H.L.6    Merfort, I.7
  • 21
    • 0029073836 scopus 로고
    • Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells
    • Chen H.C., Chou C.K., Lee S.D., Wang J.C., Yeh S.F. Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. Antiviral. Res. 27:1995;99-109.
    • (1995) Antiviral. Res. , vol.27 , pp. 99-109
    • Chen, H.C.1    Chou, C.K.2    Lee, S.D.3    Wang, J.C.4    Yeh, S.F.5
  • 23
    • 0034615908 scopus 로고    scopus 로고
    • Fungicidal activity of natural and synthetic sesquiterpene lactone analogs
    • Wedge D.E., Galindo J.C., Macias F.A. Fungicidal activity of natural and synthetic sesquiterpene lactone analogs. Phytochemistry. 53:2000;747-757.
    • (2000) Phytochemistry , vol.53 , pp. 747-757
    • Wedge, D.E.1    Galindo, J.C.2    Macias, F.A.3
  • 25
    • 0023193244 scopus 로고
    • The retinoids: A review of their clinical pharmacology and therapeutic use
    • Orfanos C.E., Ehlert R., Gollnick H. The retinoids: a review of their clinical pharmacology and therapeutic use. Drugs. 34:1987;459-503.
    • (1987) Drugs , vol.34 , pp. 459-503
    • Orfanos, C.E.1    Ehlert, R.2    Gollnick, H.3
  • 27
    • 0018741634 scopus 로고
    • Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide
    • Collins S.J., Ruscetti F.W., Gallagher R.E., Gallo R.C. Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide. J. Exp. Med. 149:1979;969-974.
    • (1979) J. Exp. Med. , vol.149 , pp. 969-974
    • Collins, S.J.1    Ruscetti, F.W.2    Gallagher, R.E.3    Gallo, R.C.4
  • 29
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB
    • Chung S.W., Kang B.Y., Kim S.H., Pak Y.K., Cho D., Trinchieri G., Kim T.S. Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB. J. Biol. Chem. 275:2000;32681-32687.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32681-32687
    • Chung, S.W.1    Kang, B.Y.2    Kim, S.H.3    Pak, Y.K.4    Cho, D.5    Trinchieri, G.6    Kim, T.S.7
  • 30
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • Wright S.D., Ramos R.A., Tobias P.S., Ulevitch R.J., Mathison J.C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249:1990;1431-1433.
    • (1990) Science , vol.249 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5
  • 31
    • 0023845249 scopus 로고
    • Effects of protein kinase inhibitors 1(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H7) and N-[2-quanidinoethyl]-5-isoquinolinesulfonamide hydrochloride (HA1004) on calcitriol-induced differentiation of HL-60 cells
    • Martell R.E., Simpson R.U., Hsu T. Effects of protein kinase inhibitors 1(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H7) and N-[2-quanidinoethyl]-5-isoquinolinesulfonamide hydrochloride (HA1004) on calcitriol-induced differentiation of HL-60 cells. Biochem. Pharmacol. 37:1988;635-640.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 635-640
    • Martell, R.E.1    Simpson, R.U.2    Hsu, T.3
  • 32
    • 0024317367 scopus 로고
    • Studies on the relationship between protein kinase C and differentiation of human promyelocytic leukemia cells induced by retinoic acid
    • Wu X.Z., Shao G.Y., Chen S., Wang X.W., Wang Z.Y. Studies on the relationship between protein kinase C and differentiation of human promyelocytic leukemia cells induced by retinoic acid. Leuk. Res. 13:1989;869-874.
    • (1989) Leuk. Res. , vol.13 , pp. 869-874
    • Wu, X.Z.1    Shao, G.Y.2    Chen, S.3    Wang, X.W.4    Wang, Z.Y.5
  • 33
    • 0033083760 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase activity is essential for all-trans-retinoic acid-induced granulocytic differentiation of HL-60 cells
    • Bertagnolo V., Neri L.M., Marchisio M., Mischiati C., Capitani S. Phosphoinositide 3-kinase activity is essential for all-trans-retinoic acid-induced granulocytic differentiation of HL-60 cells. Cancer Res. 59:1999;542-546.
    • (1999) Cancer Res. , vol.59 , pp. 542-546
    • Bertagnolo, V.1    Neri, L.M.2    Marchisio, M.3    Mischiati, C.4    Capitani, S.5
  • 34
    • 0344301937 scopus 로고    scopus 로고
    • 3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
    • 3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells. Biochem. Biophys. Res. Commun. 241:1997;419-426.
    • (1997) Biochem. Biophys. Res. Commun. , vol.241 , pp. 419-426
    • Marcinkowska, E.1    Wiedlocha, A.2    Radzikowski, C.3
  • 35
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J. Biol. Chem. 270:1995;27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 36
    • 0035084149 scopus 로고    scopus 로고
    • A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-κB by targeting I kappa B phosphorylation
    • Koo T.H., Lee J.H., Park Y.J., Hong Y.S., Kim H.S., Kim K.W., Lee J.J. A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-κB by targeting I kappa B phosphorylation. Planta Med. 67:2001;103-107.
    • (2001) Planta Med. , vol.67 , pp. 103-107
    • Koo, T.H.1    Lee, J.H.2    Park, Y.J.3    Hong, Y.S.4    Kim, H.S.5    Kim, K.W.6    Lee, J.J.7
  • 37
    • 0027056213 scopus 로고
    • 3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells
    • 3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells. Anticancer Res. 12:1992;1947-1952.
    • (1992) Anticancer Res. , vol.12 , pp. 1947-1952
    • Yoshida, M.1    Tanaka, Y.2    Eguchi, T.3    Ikekawa, N.4    Saijo, N.5
  • 38
    • 0035877237 scopus 로고    scopus 로고
    • Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by silibinin: Involvement of protein kinase C
    • Kang S.N., Lee M.H., Kim K.-M., Cho D., Kim T.S. Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by silibinin: involvement of protein kinase C. Biochem. Pharmacol. 61:2001;1487-1495.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 1487-1495
    • Kang, S.N.1    Lee, M.H.2    Kim, K.-M.3    Cho, D.4    Kim, T.S.5
  • 39
    • 0035946942 scopus 로고    scopus 로고
    • Capsaicin potentiates 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells
    • Kang S.N., Chung S.W., Kim T.S. Capsaicin potentiates 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells. Eur. J. Pharmacol. 420:2001;83-90.
    • (2001) Eur. J. Pharmacol. , vol.420 , pp. 83-90
    • Kang, S.N.1    Chung, S.W.2    Kim, T.S.3
  • 41
    • 0029664540 scopus 로고    scopus 로고
    • 3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, a α-tocopherol ester of all-trans retinoic acid
    • 3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, a α-tocopherol ester of all-trans retinoic acid. Blood. 87:1996;3384-3394.
    • (1996) Blood , vol.87 , pp. 3384-3394
    • Makishima, M.1    Kanatani, Y.2    Yamamoto-Yamaguchi, Y.3    Honma, Y.4
  • 44
    • 0030611087 scopus 로고    scopus 로고
    • 3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells. A structure-function study
    • 3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells. A structure-function study. J. Biol. Chem. 272:1997;22617-22622.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22617-22622
    • Zanello, L.P.1    Norman, A.W.2
  • 46
    • 0034255656 scopus 로고    scopus 로고
    • 3-induced differentiation of human leukemia HL60 cells
    • 3-induced differentiation of human leukemia HL60 cells. Exp. Cell Res. 258:2000;425-437.
    • (2000) Exp. Cell Res. , vol.258 , pp. 425-437
    • Wang, X.1    Rao, J.2    Studzinski, G.P.3
  • 47
    • 0026059494 scopus 로고
    • In vivo and in vitro effects of helenalin on mouse hepatic microsomal cytochrome P450
    • Chapman D.E., Holbrook D.J., Chaney S.G., Hall I.H., Lee K.H. In vivo and in vitro effects of helenalin on mouse hepatic microsomal cytochrome P450. Biochem. Pharmacol. 41:1991;229-235.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 229-235
    • Chapman, D.E.1    Holbrook, D.J.2    Chaney, S.G.3    Hall, I.H.4    Lee, K.H.5
  • 48
    • 0036512763 scopus 로고    scopus 로고
    • Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines
    • Nagai F., Hiyoshi Y., Sugimachi K., Tamura H.O. Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines. Biol. Pharm. Bull. 25:2002;383-385.
    • (2002) Biol. Pharm. Bull. , vol.25 , pp. 383-385
    • Nagai, F.1    Hiyoshi, Y.2    Sugimachi, K.3    Tamura, H.O.4
  • 49
    • 0030068202 scopus 로고    scopus 로고
    • Cytochrome P450E1- and cytochrome P4502B1/2B2-catalyzed carbon tetrachloride metabolism: Effects on signal transduction as demonstrated by altered immediate-early (c-fos and c-jun) gene expression and nuclear AP-1 and NF-κB transcription factor levels
    • Gruebele A., Zawaski K., Kaplan D., Novak R.F. Cytochrome P450E1- and cytochrome P4502B1/2B2-catalyzed carbon tetrachloride metabolism: effects on signal transduction as demonstrated by altered immediate-early (c-fos and c-jun) gene expression and nuclear AP-1 and NF-κB transcription factor levels. Drug Metab. Dispos. 24:1996;15-22.
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 15-22
    • Gruebele, A.1    Zawaski, K.2    Kaplan, D.3    Novak, R.F.4
  • 50
    • 0033969839 scopus 로고    scopus 로고
    • Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Puga A., Barnes S.J., Chang C., Zhu H., Nephew K.P., Khan S.A., Shertzer H.G. Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem. Pharmacol. 59:2000;997-1005.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 997-1005
    • Puga, A.1    Barnes, S.J.2    Chang, C.3    Zhu, H.4    Nephew, K.P.5    Khan, S.A.6    Shertzer, H.G.7


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