Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis

Biochemical Pharmacology

Volumn 68, Issue 11, 2004, Pages 2177-2186

  Ishida, Seiichi ^a   Shigemoto Mogami, Yukari ^a   Shinozaki, Youichi ^a   Kagechika, Hiroyuki ^b   Shudo, Koichi ^c   Ozawa, Shogo ^a   Sawada, Jun Ichi ^a   Ohno, Yasuo ^a   Inoue, Kazuhide ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Kawasaki   (Japan)

Author keywords

All trans retinoic acid; Am80; Cell proliferation; Global gene expression profiling analysis; HL 60; PI3 kinase Akt pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RETINOIC ACID; S6 KINASE; TAMIBAROTENE; WORTMANNIN;

APOPTOSIS; ARTICLE; CATALYSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; ENZYME SUBUNIT; GENE CLUSTER; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; BENZOATES; CARRIER PROTEINS; CELL DIFFERENTIATION; GENE EXPRESSION PROFILING; HL-60 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES; TETRAHYDRONAPHTHALENES; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 7444234742     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.08.017     Document Type: Article

References (30)

1. J.-W. Zhang, J. Gu, Z.-Y. Wang, S.-J. Chen, and Z. Chen Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells J Biosci 25 2000 275 284
2. T. Tobita, A. Takeshita, K. Kitamura, K. Ohnishi, M. Yanagi, and A. Hiraoka Treatment with a new synthetic retinoid, Am80, of acute promyelocytic leukemia relapsed from complete remission induced by all-trans retinoic acid Blood 90 1997 967 973
3. M. Takeuchi, T. Yano, E. Omoto, K. Takahashi, M. Kibata, and K. Shudo Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80 Leuk Lymphoma 31 1998 441 451
4. H. Kagechika Novel synthetic retinoids and separation of the pleiotropic retinoidal activities Curr Med Chem 9 2002 591 608
5. S. Ishida, K. Shudo, S. Takada, and K. Koike A direct role of transcription factor E2F in c-myc gene expression during granulocytic and macrophage-like differentiation of HL60 cells Cell Growth Differ 6 1995 229 237
6. Y. Hashimoto, H. Kagechika, E. Kawachi, and K. Shudo Specific uptake of retinoids into human promyelocytic leukemia cells HL-60 by retinoid-specific binding protein: possibly the true retinoid receptor Jpn J Cancer Res 79 1988 473 483
7. Y. Hashimoto, M. Petkovich, M.P. Gaub, H. Kagechika, K. Shudo, and P. Chambon The retinoic acid receptors alpha and beta are expressed in the human promyelocytic leukemia cell line HL-60 Mol Endocrinol 3 1989 1046 1052
8. H. Kagechika, E. Kawachi, Y. Hashimoto, and K. Shudo Retinobenzoic acid 2. Structure-activity relationships of chalcone-4-carboxylic acids and falvone-4′-carboxylic acids J Med Chem 32 1989 834 840
9. K. Ohta, E. Kawachi, N. Inoue, H. Fukasawa, Y. Hashimoto, and A. Itai Retinoidal pyrimidinecarbosylic acids. Unexpected diaza-substituent effects in retinobenzoic acids Chem Pharm Bull (Tokyo) 48 2000 1504 1513
10. K. Toda, S. Ishida, K. Nakata, R. Matsuda, Y. Shigemoto-Mogami, and K. Fujishita Test of significant differences with a priori probability in microarray experiments Anal Sci 19 2003 1529 1535
11. J.E. Balmer, and R. Blomhoff Gene expression regulation by retinoic acid J Lipid Res 43 2002 1773 1808
12. S. Lopez-Borges, and P.A. Lazo The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumor suppressor protein Oncogene 19 2000 3656 3664
13. s6k FEBS Lett 410 1997 78 82
14. R. Lucchini, P. Vezzoni, R. Giardini, M.A. Vezzoni, M. Raineri, and L. Clerici Poly(A) polymerase distribution in normal and malignant lymphoid cells Tumori 70 1984 141 146
15. Q. Xu, and J.C. Reed Bax inihibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast Mol Cell 1 1998 337 346
16. I.H. Oh, and E.P. Reddy The myb gene family in cell growth, differentiation and apoptosis Oncogene 18 1999 3017 3033
17. E. Maldonado, R. Shiekhattar, M. Sheldon, H. Cho, R. Drapkin, and P. Rickert A human RNA polymerase II complex associated with SRB and DNA-repair proteins Nature 381 1996 86 89
18. F. Chang, J.T. Lee, P.M. Navolanic, L.S. Steelman, J.G. Shelton, and W.L. Blalock Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy Leukemia 17 2003 590 603
19. S. Ishida, Y. Shigemoto-Mogami, H. Kagechika, K. Shudo, S. Ozawa, and J. Sawada Clinically potential subclasses of retinoid synergists revealed by gene expression profiling Mol Cancer Ther 2 2003 49 58
20. C. Grandori, J. Mac, F. Siebelt, D.E. Ayer, and R.N. Eisenman Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo EMBO J 15 1996 4344 4357
21. T.L. Brandt, D.J. Fraser, S. Leal, P.M. Halandras, A.R. Kroll, and D.J. Kroll c-Myb trans-activates the human DNA topoisomerase II alpha gene promoter J Biol Chem 272 1997 6278 6284
22. K. Toda, S. Ishida, K. Nakata, R. Matsuda, Y. Shigemoto-Mogami, and S. Ozawa Improvement in reliability of probabilistic test of significant differences in genechip experiments Anal Sci 20 2004 731 733
23. L. Nagy, V.A. Thomazy, G.L. Shipley, L. Fesus, W. Lamph, and R.A. Heyman Activation of retinoid X receptors induces apoptosis in HL-60 cell lines Mol Cell Biol 15 1995 3540 3551
24. S6K protein are involved in differentiation of HL-60 cells induced by calcitriol Anticancer Res 18 1998 3507 3514
25. M. Marchisio, V. Bertagnolo, M.L. Colamussi, S. Capitani, and L.M. Neri Phospatidylinositol 3-kinase in HL-60 nuclei is bound to the nuclear matrix and increases during granulocytic differentiation Biochem Biophys Res Comm 253 1998 346 351
26. V. Bertagnolo, L.M. Neri, M. Marchisio, C. Mischiati, and S. Capitani Phosphoinositide 3-kinase activity is essential for all-trans-retinoic acid-induced granulocytic differentiation of HL-60 cells Cancer Res 59 1999 542 546
27. S. Capitani, M. Marchisio, L.M. Neri, F. Brugnoli, A. Gonelli, and V. Bertagnolo Phosphoinositide 3-kinase is associated to the nucleus of HL-60 cells and is involved in their ATRA-induced granulocytic differentiation Eur J Histochem 44 2000 61 65
28. Q. Liu, D. Schacher, C. Hurth, G.G. Freund, R. Dantzer, and K.W. Kelley Activation of phosphatidylinositol 3′-kinase by insulin-like growth factor-I rescues promyeloid cells from apoptosis and permits their differentiation into granulocytes J Immun 159 1997 829 837
29. J. Ma, Q. Liu, and Y.X. Zeng Inhibition of phosphatidylinositol 3-kinase causes apoptosis in retinoic acid differentiated HL-60 leukemia cells Cell Cycle 3 2004 67 70
30. Y. Hashimoto Structural development of synthetic retinoids and thalidomide-related molecules Cancer Chemother Pharmacol 52 2003 S16 S23