-
1
-
-
0035342676
-
3 that resist metabolism through C-24 oxidation and C-3 epimerization pathways
-
3 that resist metabolism through C-24 oxidation and C-3 epimerization pathways. Steroids 2001; 66:463-71.
-
(2001)
Steroids
, vol.66
, pp. 463-471
-
-
Uskokovic, M.R.1
Norman, A.W.2
Manchand, P.S.3
Studzinski, G.P.4
Campbell, M.J.5
Koeffler, H.P.6
Takeuchi, A.7
Siu-Caldera, M.L.8
Rao, D.S.9
Reddy, G.S.10
-
2
-
-
33645211141
-
3 and participates in its anti-apoptotic effect and cell cycle control in differentiating HL60 cells
-
3 and participates in its anti-apoptotic effect and cell cycle control in differentiating HL60 cells. Cell Cycle 2006; 5:447-51.
-
(2006)
Cell Cycle
, vol.5
, pp. 447-451
-
-
Zhang, Y.1
Zhang, J.2
Studzinski, G.P.3
-
3
-
-
0037321791
-
Efficacy of Vitamin D compounds to modulate estrogen receptor negative breast cancer growth and invasion
-
Flanagan L, Packman K, Juba B, O'Neill S, Tenniswood M, Welsh J. Efficacy of Vitamin D compounds to modulate estrogen receptor negative breast cancer growth and invasion. J Steroid Biochem Mol Biol 2003; 84:181-92.
-
(2003)
J Steroid Biochem Mol Biol
, vol.84
, pp. 181-192
-
-
Flanagan, L.1
Packman, K.2
Juba, B.3
O'Neill, S.4
Tenniswood, M.5
Welsh, J.6
-
6
-
-
0642336649
-
Evaluation of vitamin D analogs as therapeutic agents for prostate cancer
-
Chen TC, Holick MF, Lokeshwar BL, Burnstein KL, Schwartz GG. Evaluation of vitamin D analogs as therapeutic agents for prostate cancer. Recent Results Cancer Res 2003; 164:273-88.
-
(2003)
Recent Results Cancer Res
, vol.164
, pp. 273-288
-
-
Chen, T.C.1
Holick, M.F.2
Lokeshwar, B.L.3
Burnstein, K.L.4
Schwartz, G.G.5
-
10
-
-
0034255656
-
3-induced differentiation of human leukemia HL60 cells
-
3-induced differentiation of human leukemia HL60 cells. Exp Cell Res 2000; 258:425-37.
-
(2000)
Exp Cell Res
, vol.258
, pp. 425-437
-
-
Wang, X.1
Rao, J.2
Studzinski, G.P.3
-
12
-
-
0032007110
-
Induction of the differentiation of HL-60 promyelocytic leukemia cells by nonsteroidal anti-inflammatory agents in combination with low levels of vitamin D3
-
Sokoloski JA, Sartorelli AC. Induction of the differentiation of HL-60 promyelocytic leukemia cells by nonsteroidal anti-inflammatory agents in combination with low levels of vitamin D3. Leuk Res 1998; 22:153-61.
-
(1998)
Leuk Res
, vol.22
, pp. 153-161
-
-
Sokoloski, J.A.1
Sartorelli, A.C.2
-
13
-
-
35349016919
-
Chemoprevention of colorectal cancer
-
Das D, Arber N, Jankowski JA. Chemoprevention of colorectal cancer. Digestion 2007; 76:51-67.
-
(2007)
Digestion
, vol.76
, pp. 51-67
-
-
Das, D.1
Arber, N.2
Jankowski, J.A.3
-
14
-
-
34548220566
-
Prevention of cancer in the upper gastrointestinal tract with COX-inhibition. Still an option?
-
Jimenez P, Garcia A, Santander S, Piazuelo E. Prevention of cancer in the upper gastrointestinal tract with COX-inhibition. Still an option? Curr Pharm Des 2007; 13:2261-73.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 2261-2273
-
-
Jimenez, P.1
Garcia, A.2
Santander, S.3
Piazuelo, E.4
-
15
-
-
34047199255
-
Inflammatory mediators and nuclear receptor signaling in colorectal cancer
-
Wang D, DuBois RN. Inflammatory mediators and nuclear receptor signaling in colorectal cancer. Cell Cycle 2007; 6:682-5.
-
(2007)
Cell Cycle
, vol.6
, pp. 682-685
-
-
Wang, D.1
DuBois, R.N.2
-
17
-
-
33749247432
-
3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK module
-
3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK module. J Cell Physiol 2006; 209:253-60.
-
(2006)
J Cell Physiol
, vol.209
, pp. 253-260
-
-
Wang, X.1
Studzinski, G.P.2
-
19
-
-
0021992164
-
Human leukemic models of myelomonocytic development: A review of the HL-60 and U937 cell lines
-
Harris P, Ralph P. Human leukemic models of myelomonocytic development: a review of the HL-60 and U937 cell lines. J Leukoc Biol 1985; 37:407-22.
-
(1985)
J Leukoc Biol
, vol.37
, pp. 407-422
-
-
Harris, P.1
Ralph, P.2
-
20
-
-
0025963002
-
The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation
-
Auwerx J. The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiation. Experientia 1991; 47:22-31.
-
(1991)
Experientia
, vol.47
, pp. 22-31
-
-
Auwerx, J.1
-
21
-
-
1642498134
-
Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts
-
Mifflin RC, Saada JI, Di Mari JF, Valentich JD, Adegboyega PA, Powell DW. Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts. Mol Pharmacol 2004; 65:470-8.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 470-478
-
-
Mifflin, R.C.1
Saada, J.I.2
Di Mari, J.F.3
Valentich, J.D.4
Adegboyega, P.A.5
Powell, D.W.6
-
22
-
-
0038442155
-
Prenatal effects of DuP-697-the irreversible, highly selective cyclooxygenase-2 inhibitor
-
Burdan F, Dudka J, Szumilo J, Korobowicz A, Klepacz L. Prenatal effects of DuP-697-the irreversible, highly selective cyclooxygenase-2 inhibitor. Reprod Toxicol 2003; 17:413-9.
-
(2003)
Reprod Toxicol
, vol.17
, pp. 413-419
-
-
Burdan, F.1
Dudka, J.2
Szumilo, J.3
Korobowicz, A.4
Klepacz, L.5
-
23
-
-
0027375910
-
The anti-platelet actions of FR122047, a novel cyclooxygenase inhibitor
-
Dohi M, Sakata Y, Seki J, Namikawa Y, Fujisaki J, Tanaka A, Takasugi H, Motoyama Y, Yoshida K. The anti-platelet actions of FR122047, a novel cyclooxygenase inhibitor. Eur J Pharmacol 1993; 243:179-84.
-
(1993)
Eur J Pharmacol
, vol.243
, pp. 179-184
-
-
Dohi, M.1
Sakata, Y.2
Seki, J.3
Namikawa, Y.4
Fujisaki, J.5
Tanaka, A.6
Takasugi, H.7
Motoyama, Y.8
Yoshida, K.9
-
24
-
-
0015237263
-
Indomethacin and aspirin abolish prostaglandin release from the spleen
-
Ferreira SH, Moncada S, Vane JR. Indomethacin and aspirin abolish prostaglandin release from the spleen. Nat New Biol 1971; 231:237-9.
-
(1971)
Nat New Biol
, vol.231
, pp. 237-239
-
-
Ferreira, S.H.1
Moncada, S.2
Vane, J.R.3
-
25
-
-
0034981648
-
Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells
-
Wang X, Studzinski GP. Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells. J Cell Biochem 2001; 82:68-77.
-
(2001)
J Cell Biochem
, vol.82
, pp. 68-77
-
-
Wang, X.1
Studzinski, G.P.2
-
26
-
-
33747814469
-
Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: Involvement of reactive oxygen species
-
Tanaka T, Kurose A, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z. Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species. Cell Cycle 2006; 5:1669-74.
-
(2006)
Cell Cycle
, vol.5
, pp. 1669-1674
-
-
Tanaka, T.1
Kurose, A.2
Halicka, H.D.3
Huang, X.4
Traganos, F.5
Darzynkiewicz, Z.6
-
29
-
-
0019407926
-
Expression of myeloid differentiation antigens on normal and malignant myeloid cells
-
Griffin JD, Ritz J, Nadler LM, Schlossman SF. Expression of myeloid differentiation antigens on normal and malignant myeloid cells. J Clin Invest 1981; 68:932-41.
-
(1981)
J Clin Invest
, vol.68
, pp. 932-941
-
-
Griffin, J.D.1
Ritz, J.2
Nadler, L.M.3
Schlossman, S.F.4
-
30
-
-
0029973342
-
Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family
-
Bunce CM, Mountford JC, French PJ, Mole DJ, Durham J, Michell RH, Brown G. Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family. Biochim Biophys Acta 1996; 1311:189-98.
-
(1996)
Biochim Biophys Acta
, vol.1311
, pp. 189-198
-
-
Bunce, C.M.1
Mountford, J.C.2
French, P.J.3
Mole, D.J.4
Durham, J.5
Michell, R.H.6
Brown, G.7
-
32
-
-
0035062018
-
Evidence that activation of MEK1,2/erk1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells
-
Marcinkowska E. Evidence that activation of MEK1,2/erk1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells. Anticancer Res 2001; 21:499-504.
-
(2001)
Anticancer Res
, vol.21
, pp. 499-504
-
-
Marcinkowska, E.1
-
33
-
-
34547657573
-
Differentiation-inducing potency of the seco-steroid JK-1624F2-2 can be increased by combination with an antioxidant and a p38MAPK inhibitor which upregulates the JNK pathway
-
Zhang J, Posner GH, Danilenko M, Studzinski GP. Differentiation-inducing potency of the seco-steroid JK-1624F2-2 can be increased by combination with an antioxidant and a p38MAPK inhibitor which upregulates the JNK pathway. J Steroid Biochem Mol Biol 2007; 105:140-9.
-
(2007)
J Steroid Biochem Mol Biol
, vol.105
, pp. 140-149
-
-
Zhang, J.1
Posner, G.H.2
Danilenko, M.3
Studzinski, G.P.4
-
34
-
-
33847106014
-
Thromboembolic cardiovascular risk among arthritis patients using cyclooxygenase-2-selective inhibitor or nonselective cyclooxygenase inhibitor nonsteroidal anti-inflammatory drugs
-
Spalding WM, Reeves MJ, Whelton A. Thromboembolic cardiovascular risk among arthritis patients using cyclooxygenase-2-selective inhibitor or nonselective cyclooxygenase inhibitor nonsteroidal anti-inflammatory drugs. Am J Ther 2007; 14:3-12.
-
(2007)
Am J Ther
, vol.14
, pp. 3-12
-
-
Spalding, W.M.1
Reeves, M.J.2
Whelton, A.3
-
35
-
-
0036396802
-
Selective cyclo-oxygenase-2 inhibitors and myocardial infarction: How strong is the link?
-
Howes LG, Krum H. Selective cyclo-oxygenase-2 inhibitors and myocardial infarction: how strong is the link? Drug Saf 2002; 25:829-35.
-
(2002)
Drug Saf
, vol.25
, pp. 829-835
-
-
Howes, L.G.1
Krum, H.2
-
36
-
-
0142154979
-
Balancing gastroprotection and cardioprotection with selective cyclo-oxygenase-2 inhibitors: Clinical implications
-
Meagher EA. Balancing gastroprotection and cardioprotection with selective cyclo-oxygenase-2 inhibitors: clinical implications. Drug Saf 2003; 26:913-24.
-
(2003)
Drug Saf
, vol.26
, pp. 913-924
-
-
Meagher, E.A.1
-
37
-
-
33746595865
-
Mechanisms of vitamin D-mediated growth inhibition in prostate cancer cells: Inhibition of the prostaglandin pathway
-
Moreno J, Krishnan AV, Peehl DM, Feldman D. Mechanisms of vitamin D-mediated growth inhibition in prostate cancer cells: inhibition of the prostaglandin pathway. Anticancer Res 2006; 26:2525-30.
-
(2006)
Anticancer Res
, vol.26
, pp. 2525-2530
-
-
Moreno, J.1
Krishnan, A.V.2
Peehl, D.M.3
Feldman, D.4
-
38
-
-
24744452645
-
Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells
-
Moreno J, Krishnan AV, Swami S, Nonn L, Peehl DM, Feldman D. Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. Cancer Res 2005; 65:7917-25.
-
(2005)
Cancer Res
, vol.65
, pp. 7917-7925
-
-
Moreno, J.1
Krishnan, A.V.2
Swami, S.3
Nonn, L.4
Peehl, D.M.5
Feldman, D.6
-
39
-
-
0040668345
-
Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells
-
Marcinkowska E, Kutner A. Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells. Acta Biochim Pol 2002; 49:393-406.
-
(2002)
Acta Biochim Pol
, vol.49
, pp. 393-406
-
-
Marcinkowska, E.1
Kutner, A.2
-
40
-
-
27544483645
-
The rationale for deltanoids in therapy for myeloid leukemia: Role of KSR-MAPK-C/EBP pathway
-
Studzinski GP, Wang X, Ji Y, Wang Q, Zhang Y, Kutner A, Harrison JS. The rationale for deltanoids in therapy for myeloid leukemia: role of KSR-MAPK-C/EBP pathway. J Steroid Biochem Mol Biol 2005; 97:47-55.
-
(2005)
J Steroid Biochem Mol Biol
, vol.97
, pp. 47-55
-
-
Studzinski, G.P.1
Wang, X.2
Ji, Y.3
Wang, Q.4
Zhang, Y.5
Kutner, A.6
Harrison, J.S.7
-
41
-
-
33749237426
-
3 in human leukemia HL60 cells through a vitamin D response element in the 5′-flanking region
-
3 in human leukemia HL60 cells through a vitamin D response element in the 5′-flanking region. Oncogene 2006; 25:7078-85.
-
(2006)
Oncogene
, vol.25
, pp. 7078-7085
-
-
Wang, X.1
Wang, T.T.2
White, J.H.3
Studzinski, G.P.4
-
42
-
-
0035881255
-
Phosphorylation of raf-1 by kinase suppressor of ras is inhibited by "MEK-specific" inhibitors PD 098059 and U0126 in differentiating HL60 cells
-
Wang X, Studzinski GP. Phosphorylation of raf-1 by kinase suppressor of ras is inhibited by "MEK-specific" inhibitors PD 098059 and U0126 in differentiating HL60 cells. Exp Cell Res 2001; 268:294-300.
-
(2001)
Exp Cell Res
, vol.268
, pp. 294-300
-
-
Wang, X.1
Studzinski, G.P.2
-
45
-
-
0029584327
-
-
Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM. KSR, a novel protein kinase required for RAS signal transduction. Cell 1995; 83:879-88.
-
Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM. KSR, a novel protein kinase required for RAS signal transduction. Cell 1995; 83:879-88.
-
-
-
-
46
-
-
0037083988
-
KSR is a scaffold required for activation of the ERK/MAPK module
-
Roy F, Laberge G, Douziech M, Ferland-McCollough D, Therrien M. KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev 2002; 16:427-38.
-
(2002)
Genes Dev
, vol.16
, pp. 427-438
-
-
Roy, F.1
Laberge, G.2
Douziech, M.3
Ferland-McCollough, D.4
Therrien, M.5
-
47
-
-
38349191618
-
NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts
-
Selvendiran K, Bratasz A, Tong L, Ignarro L, Kuppusamy P. NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts. Cell Cycle 2008; 7.
-
(2008)
Cell Cycle
, pp. 7
-
-
Selvendiran, K.1
Bratasz, A.2
Tong, L.3
Ignarro, L.4
Kuppusamy, P.5
-
48
-
-
38749145215
-
Tetrahydrofurandiol stimulation of phospholipase A2, lipoxygenase, and cyclooxygenase gene expression and MCF-7 human breast cancer cell proliferation
-
Markaverich BM, Crowley J, Rodriquez M, Shoulars K, Thompson T. Tetrahydrofurandiol stimulation of phospholipase A2, lipoxygenase, and cyclooxygenase gene expression and MCF-7 human breast cancer cell proliferation. Environ Health Perspect 2007; 115:1727-31.
-
(2007)
Environ Health Perspect
, vol.115
, pp. 1727-1731
-
-
Markaverich, B.M.1
Crowley, J.2
Rodriquez, M.3
Shoulars, K.4
Thompson, T.5
-
49
-
-
0026701092
-
Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells
-
Gallego C, Gupta SK, Heasley LE, Qian NX, Johnson GL. Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells. Proc Natl Acad Sci USA 1992; 89:7355-9.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7355-7359
-
-
Gallego, C.1
Gupta, S.K.2
Heasley, L.E.3
Qian, N.X.4
Johnson, G.L.5
-
50
-
-
0026647749
-
Raf-1 activates MAP kinase-kinase
-
Kyriakis JM, App H, Zhang XF, Banerjee P, Brautigan DL, Rapp UR, Avruch J. Raf-1 activates MAP kinase-kinase. Nature 1992; 358:417-21.
-
(1992)
Nature
, vol.358
, pp. 417-421
-
-
Kyriakis, J.M.1
App, H.2
Zhang, X.F.3
Banerjee, P.4
Brautigan, D.L.5
Rapp, U.R.6
Avruch, J.7
|