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Volumn 88, Issue 4, 2009, Pages 724-728

The role of proteolytic cellular systems in trabecular meshwork homeostasis

Author keywords

aging; calpains; lon proteases; lysosomes; POAG; proteasome; proteolytic systems; trabecular meshwork

Indexed keywords

CALPAIN 1; CALPAIN 2; PROTEASOME; REACTIVE OXYGEN METABOLITE; UBIQUITIN;

EID: 64249133695     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.11.002     Document Type: Review
Times cited : (30)

References (77)
  • 1
    • 33745675536 scopus 로고    scopus 로고
    • Mitochondrial abnormalities in patients with primary open-angle glaucoma
    • Abu-Amero K.K., Morales J., and Bosley T.M. Mitochondrial abnormalities in patients with primary open-angle glaucoma. Invest. Ophthalmol. Vis. Sci. 47 (2006) 2533-2541
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 2533-2541
    • Abu-Amero, K.K.1    Morales, J.2    Bosley, T.M.3
  • 2
    • 20444371356 scopus 로고    scopus 로고
    • Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227
    • Aroca-Aguilar J.D., Sanchez-Sanchez F., Ghosh S., Coca-Prados M., and Escribano J. Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227. J. Biol. Chem. 280 (2005) 21043-21051
    • (2005) J. Biol. Chem. , vol.280 , pp. 21043-21051
    • Aroca-Aguilar, J.D.1    Sanchez-Sanchez, F.2    Ghosh, S.3    Coca-Prados, M.4    Escribano, J.5
  • 3
    • 46649083004 scopus 로고    scopus 로고
    • Oxidative and nitrative stress markers in glaucoma
    • Aslan M., Cort A., and Yucel I. Oxidative and nitrative stress markers in glaucoma. Free Radic. Biol. Med. 45 (2008) 367-376
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 367-376
    • Aslan, M.1    Cort, A.2    Yucel, I.3
  • 5
    • 0036830228 scopus 로고    scopus 로고
    • The neuropathogenic contributions of lysosomal dysfunction
    • Bahr B.A., and Bendiske J. The neuropathogenic contributions of lysosomal dysfunction. J. Neurochem. 83 (2002) 481-489
    • (2002) J. Neurochem. , vol.83 , pp. 481-489
    • Bahr, B.A.1    Bendiske, J.2
  • 6
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • Barja G. Free radicals and aging. Trends Neurosci. 27 (2004) 595-600
    • (2004) Trends Neurosci. , vol.27 , pp. 595-600
    • Barja, G.1
  • 7
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., and Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78 (1998) 547-581
    • (1998) Physiol. Rev. , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 10
    • 15744384860 scopus 로고    scopus 로고
    • Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
    • Bota D.A., Ngo J.K., and Davies K.J. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic. Biol. Med. 38 (2005) 665-677
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 665-677
    • Bota, D.A.1    Ngo, J.K.2    Davies, K.J.3
  • 11
    • 0037021453 scopus 로고    scopus 로고
    • Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress
    • Bota D.A., Van Remmen H., and Davies K.J. Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress. FEBS Lett. 532 (2002) 103-106
    • (2002) FEBS Lett. , vol.532 , pp. 103-106
    • Bota, D.A.1    Van Remmen, H.2    Davies, K.J.3
  • 12
    • 40149100476 scopus 로고    scopus 로고
    • Regulation of proteasome-mediated protein degradation during oxidative stress and aging
    • Breusing N., and Grune T. Regulation of proteasome-mediated protein degradation during oxidative stress and aging. Biol. Chem. 389 (2008) 203-209
    • (2008) Biol. Chem. , vol.389 , pp. 203-209
    • Breusing, N.1    Grune, T.2
  • 13
    • 33744972513 scopus 로고    scopus 로고
    • Mitochondrial protein oxidation and degradation in response to oxidative stress and aging
    • Bulteau A.L., Szweda L.I., and Friguet B. Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Exp. Gerontol. 41 (2006) 653-657
    • (2006) Exp. Gerontol. , vol.41 , pp. 653-657
    • Bulteau, A.L.1    Szweda, L.I.2    Friguet, B.3
  • 14
    • 0034815847 scopus 로고    scopus 로고
    • Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma
    • Caballero M., and Borras T. Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma. Biochem. Biophys. Res. Commun. 282 (2001) 662-670
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 662-670
    • Caballero, M.1    Borras, T.2
  • 16
    • 0042594473 scopus 로고    scopus 로고
    • Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells
    • Caballero M., Liton P.B., Epstein D.L., and Gonzalez P. Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells. Biochem. Biophys. Res. Commun. 308 (2003) 346-352
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 346-352
    • Caballero, M.1    Liton, P.B.2    Epstein, D.L.3    Gonzalez, P.4
  • 19
    • 0004034753 scopus 로고
    • Ciechanover A.J., and Schwartz A.L. (Eds), Wiley-Liss, New York
    • In: Ciechanover A.J., and Schwartz A.L. (Eds). Cellular Proteolytic Systems (1994), Wiley-Liss, New York
    • (1994) Cellular Proteolytic Systems
  • 21
    • 33646189469 scopus 로고    scopus 로고
    • Melanin in the trabecular meshwork is associated with age, POAG but not Latanoprost treatment. A masked morphometric study
    • Cracknell K.P., Grierson I., Hogg P., Majekodunmi A.A., Watson P., and Marmion V. Melanin in the trabecular meshwork is associated with age, POAG but not Latanoprost treatment. A masked morphometric study. Exp. Eye Res. 82 (2006) 986-993
    • (2006) Exp. Eye Res. , vol.82 , pp. 986-993
    • Cracknell, K.P.1    Grierson, I.2    Hogg, P.3    Majekodunmi, A.A.4    Watson, P.5    Marmion, V.6
  • 22
    • 0001944263 scopus 로고    scopus 로고
    • How do intracellular proteolytic systems change with age?
    • Cuervo A.M., and Dice J.F. How do intracellular proteolytic systems change with age?. Front Biosci. 3 (1998) D25-D43
    • (1998) Front Biosci. , vol.3
    • Cuervo, A.M.1    Dice, J.F.2
  • 24
    • 38449099679 scopus 로고    scopus 로고
    • Role of proteasomes in disease
    • Dahlmann B. Role of proteasomes in disease. BMC Biochem. 8 Suppl. 1 (2007) S3
    • (2007) BMC Biochem. , vol.8 , Issue.SUPPL. 1
    • Dahlmann, B.1
  • 30
    • 38849127441 scopus 로고    scopus 로고
    • Isolevuglandin-modified proteins, including elevated levels of inactive calpain-1, accumulate in glaucomatous trabecular meshwork
    • Govindarajan B., Laird J., Salomon R.G., and Bhattacharya S.K. Isolevuglandin-modified proteins, including elevated levels of inactive calpain-1, accumulate in glaucomatous trabecular meshwork. Biochemistry 47 (2008) 817-825
    • (2008) Biochemistry , vol.47 , pp. 817-825
    • Govindarajan, B.1    Laird, J.2    Salomon, R.G.3    Bhattacharya, S.K.4
  • 32
    • 34249864120 scopus 로고    scopus 로고
    • A proteasome for all occasions
    • Hanna J., and Finley D. A proteasome for all occasions. FEBS Lett. 581 (2007) 2854-2861
    • (2007) FEBS Lett. , vol.581 , pp. 2854-2861
    • Hanna, J.1    Finley, D.2
  • 33
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956) 298-300
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 34
    • 0015319592 scopus 로고
    • The biologic clock: the mitochondria?
    • Harman D. The biologic clock: the mitochondria?. J. Am. Geriatr. Soc. 20 (1972) 145-147
    • (1972) J. Am. Geriatr. Soc. , vol.20 , pp. 145-147
    • Harman, D.1
  • 35
    • 45549087104 scopus 로고    scopus 로고
    • Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants
    • He Y., Leung K.W., Zhang Y.H., Duan S., Zhong X.F., Jiang R.Z., Peng Z., Tombran-Tink J., and Ge J. Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants. Invest. Ophthalmol. Vis. Sci. 49 (2008) 1447-1458
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 1447-1458
    • He, Y.1    Leung, K.W.2    Zhang, Y.H.3    Duan, S.4    Zhong, X.F.5    Jiang, R.Z.6    Peng, Z.7    Tombran-Tink, J.8    Ge, J.9
  • 36
    • 0037938809 scopus 로고    scopus 로고
    • Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients
    • Izzotti A., Sacca S.C., Cartiglia C., and De Flora S. Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients. Am. J. Med. 114 (2003) 638-646
    • (2003) Am. J. Med. , vol.114 , pp. 638-646
    • Izzotti, A.1    Sacca, S.C.2    Cartiglia, C.3    De Flora, S.4
  • 38
    • 0344983870 scopus 로고    scopus 로고
    • Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells
    • Joe M.K., Sohn S., Hur W., Moon Y., Choi Y.R., and Kee C. Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells. Biochem. Biophys. Res. Commun. 312 (2003) 592-600
    • (2003) Biochem. Biophys. Res. Commun. , vol.312 , pp. 592-600
    • Joe, M.K.1    Sohn, S.2    Hur, W.3    Moon, Y.4    Choi, Y.R.5    Kee, C.6
  • 39
    • 34249827861 scopus 로고    scopus 로고
    • Oxidized proteins: intracellular distribution and recognition by the proteasome
    • Jung T., Bader N., and Grune T. Oxidized proteins: intracellular distribution and recognition by the proteasome. Arch. Biochem. Biophys. 462 (2007) 231-237
    • (2007) Arch. Biochem. Biophys. , vol.462 , pp. 231-237
    • Jung, T.1    Bader, N.2    Grune, T.3
  • 40
    • 34047265829 scopus 로고    scopus 로고
    • Effects of lipid peroxidation-related protein modifications on RPE lysosomal functions and POS phagocytosis
    • Kaemmerer E., Schutt F., Krohne T.U., Holz F.G., and Kopitz J. Effects of lipid peroxidation-related protein modifications on RPE lysosomal functions and POS phagocytosis. Invest. Ophthalmol. Vis. Sci. 48 (2007) 1342-1347
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 1342-1347
    • Kaemmerer, E.1    Schutt, F.2    Krohne, T.U.3    Holz, F.G.4    Kopitz, J.5
  • 43
    • 34247266702 scopus 로고    scopus 로고
    • Oxidative stress in glaucoma: a burden of evidence
    • Kumar D.M., and Agarwal N. Oxidative stress in glaucoma: a burden of evidence. J. Glaucoma 16 (2007) 334-343
    • (2007) J. Glaucoma , vol.16 , pp. 334-343
    • Kumar, D.M.1    Agarwal, N.2
  • 44
    • 0033730616 scopus 로고    scopus 로고
    • Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells
    • Kurz D.J., Decary S., Hong Y., and Erusalimsky J.D. Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. J. Cell Sci. 113 Pt 20 (2000) 3613-3622
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 20 , pp. 3613-3622
    • Kurz, D.J.1    Decary, S.2    Hong, Y.3    Erusalimsky, J.D.4
  • 45
    • 37349078627 scopus 로고    scopus 로고
    • Risk factors for incident open-angle glaucoma: the Barbados eye studies
    • Leske M.C., Wu S.Y., Hennis A., Honkanen R., and Nemesure B. Risk factors for incident open-angle glaucoma: the Barbados eye studies. Ophthalmology 115 (2008) 85-93
    • (2008) Ophthalmology , vol.115 , pp. 85-93
    • Leske, M.C.1    Wu, S.Y.2    Hennis, A.3    Honkanen, R.4    Nemesure, B.5
  • 46
    • 37349056711 scopus 로고    scopus 로고
    • Sustained stress response after oxidative stress in trabecular meshwork cells
    • Li G., Luna C., Liton P.B., Navarro I., Epstein D.L., and Gonzalez P. Sustained stress response after oxidative stress in trabecular meshwork cells. Mol. Vis. 13 (2007) 2282-2288
    • (2007) Mol. Vis. , vol.13 , pp. 2282-2288
    • Li, G.1    Luna, C.2    Liton, P.B.3    Navarro, I.4    Epstein, D.L.5    Gonzalez, P.6
  • 48
    • 53149093231 scopus 로고    scopus 로고
    • Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress
    • Liton P.B., Lin Y., Luna C., Li G., Gonzalez P., and Epstein D.L. Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress. Invest. Ophthalmol. Vis. Sci. 49 (2008) 3961-3969
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3961-3969
    • Liton, P.B.1    Lin, Y.2    Luna, C.3    Li, G.4    Gonzalez, P.5    Epstein, D.L.6
  • 49
    • 33745885317 scopus 로고    scopus 로고
    • Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue
    • Liton P.B., Luna C., Challa P., Epstein D.L., and Gonzalez P. Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue. Mol. Vis. 12 (2006) 774-790
    • (2006) Mol. Vis. , vol.12 , pp. 774-790
    • Liton, P.B.1    Luna, C.2    Challa, P.3    Epstein, D.L.4    Gonzalez, P.5
  • 50
    • 2942718944 scopus 로고    scopus 로고
    • Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma
    • Liu Y., and Vollrath D. Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma. Hum. Mol. Genet. 13 (2004) 1193-1204
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 1193-1204
    • Liu, Y.1    Vollrath, D.2
  • 51
    • 0002876010 scopus 로고    scopus 로고
    • Morphology of aqueous outlfow pathways in normal and glaucomatous eyes
    • Ritch R., Shields M.B., and Krupin T. (Eds) St. Louis, Mosby. pp. 89-123
    • Luetjen-Drecoll E., and Rohen J.W. Morphology of aqueous outlfow pathways in normal and glaucomatous eyes. In: Ritch R., Shields M.B., and Krupin T. (Eds). The Glaucomas (1996) St. Louis, Mosby. pp. 89-123
    • (1996) The Glaucomas
    • Luetjen-Drecoll, E.1    Rohen, J.W.2
  • 55
    • 36549006049 scopus 로고    scopus 로고
    • Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging
    • Ngo J.K., and Davies K.J. Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging. Ann. N Y Acad. Sci. 1119 (2007) 78-87
    • (2007) Ann. N Y Acad. Sci. , vol.1119 , pp. 78-87
    • Ngo, J.K.1    Davies, K.J.2
  • 56
    • 0141762744 scopus 로고    scopus 로고
    • The calpains in aging and aging-related diseases
    • Nixon R.A. The calpains in aging and aging-related diseases. Ageing Res. Rev. 2 (2003) 407-418
    • (2003) Ageing Res. Rev. , vol.2 , pp. 407-418
    • Nixon, R.A.1
  • 57
    • 0023711225 scopus 로고
    • Glaucoma as an early complication of Hurler's disease
    • Nowaczyk M.J., Clarke J.T., and Morin J.D. Glaucoma as an early complication of Hurler's disease. Arch. Dis. Child. 63 (1988) 1091-1093
    • (1988) Arch. Dis. Child. , vol.63 , pp. 1091-1093
    • Nowaczyk, M.J.1    Clarke, J.T.2    Morin, J.D.3
  • 58
    • 0020026805 scopus 로고
    • Presence of matrix vesicles in the trabecular meshwork of glaucomatous eyes
    • Rohen J.W. Presence of matrix vesicles in the trabecular meshwork of glaucomatous eyes. Graefes Arch. Clin. Exp. Ophthalmol. 218 (1982) 171-176
    • (1982) Graefes Arch. Clin. Exp. Ophthalmol. , vol.218 , pp. 171-176
    • Rohen, J.W.1
  • 59
  • 60
    • 16844379509 scopus 로고    scopus 로고
    • Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma
    • Sacca S.C., Pascotto A., Camicione P., Capris P., and Izzotti A. Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma. Arch. Ophthalmol. 123 (2005) 458-463
    • (2005) Arch. Ophthalmol. , vol.123 , pp. 458-463
    • Sacca, S.C.1    Pascotto, A.2    Camicione, P.3    Capris, P.4    Izzotti, A.5
  • 61
    • 34948890141 scopus 로고    scopus 로고
    • Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease
    • Sanchez-Sanchez F., Martinez-Redondo F., Aroca-Aguilar J.D., Coca-Prados M., and Escribano J. Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease. J. Biol. Chem. 282 (2007) 27810-27824
    • (2007) J. Biol. Chem. , vol.282 , pp. 27810-27824
    • Sanchez-Sanchez, F.1    Martinez-Redondo, F.2    Aroca-Aguilar, J.D.3    Coca-Prados, M.4    Escribano, J.5
  • 63
    • 0016322191 scopus 로고
    • The ageing, growth and death of cells
    • Sheldrake A.R. The ageing, growth and death of cells. Nature 250 (1974) 381-385
    • (1974) Nature , vol.250 , pp. 381-385
    • Sheldrake, A.R.1
  • 65
    • 0033674181 scopus 로고    scopus 로고
    • Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II-aging of nondividing cells
    • Sitte N., Merker K., Von Zglinicki T., Davies K.J., and Grune T. Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II-aging of nondividing cells. Faseb J. 14 (2000) 2503-2510
    • (2000) Faseb J. , vol.14 , pp. 2503-2510
    • Sitte, N.1    Merker, K.2    Von Zglinicki, T.3    Davies, K.J.4    Grune, T.5
  • 67
    • 0031812476 scopus 로고    scopus 로고
    • Lipofuscin accumulation in cultured retinal pigment epithelial cells reduces their phagocytic capacity
    • Sundelin S., Wihlmark U., Nilsson S.E., and Brunk U.T. Lipofuscin accumulation in cultured retinal pigment epithelial cells reduces their phagocytic capacity. Curr. Eye Res. 17 (1998) 851-857
    • (1998) Curr. Eye Res. , vol.17 , pp. 851-857
    • Sundelin, S.1    Wihlmark, U.2    Nilsson, S.E.3    Brunk, U.T.4
  • 68
    • 0842328803 scopus 로고    scopus 로고
    • Structure, activation, and biology of calpain
    • Suzuki K., Hata S., Kawabata Y., and Sorimachi H. Structure, activation, and biology of calpain. Diabetes 53 Suppl. 1 (2004) S12-S18
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Suzuki, K.1    Hata, S.2    Kawabata, Y.3    Sorimachi, H.4
  • 69
    • 0035063178 scopus 로고    scopus 로고
    • Garbage catastrophe theory of aging: imperfect removal of oxidative damage?
    • Terman A. Garbage catastrophe theory of aging: imperfect removal of oxidative damage?. Redox Rep. 6 (2001) 15-26
    • (2001) Redox Rep. , vol.6 , pp. 15-26
    • Terman, A.1
  • 70
    • 0032821609 scopus 로고    scopus 로고
    • Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress
    • Terman A., Abrahamsson N., and Brunk U.T. Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress. Exp. Gerontol. 34 (1999) 755-770
    • (1999) Exp. Gerontol. , vol.34 , pp. 755-770
    • Terman, A.1    Abrahamsson, N.2    Brunk, U.T.3
  • 71
    • 33644641768 scopus 로고    scopus 로고
    • Oxidative stress, accumulation of biological 'garbage', and aging
    • Terman A., and Brunk U.T. Oxidative stress, accumulation of biological 'garbage', and aging. Antioxid. Redox. Signal. 8 (2006) 197-204
    • (2006) Antioxid. Redox. Signal. , vol.8 , pp. 197-204
    • Terman, A.1    Brunk, U.T.2
  • 72
  • 73
    • 0035099269 scopus 로고    scopus 로고
    • Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype
    • Wang N., Chintala S.K., Fini M.E., and Schuman J.S. Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nat. Med. 7 (2001) 304-309
    • (2001) Nat. Med. , vol.7 , pp. 304-309
    • Wang, N.1    Chintala, S.K.2    Fini, M.E.3    Schuman, J.S.4
  • 74
    • 0025765168 scopus 로고
    • Lysosomal enzyme activity in human aqueous humor
    • Weinreb R.N., Jeng S., and Miller A.L. Lysosomal enzyme activity in human aqueous humor. Clin. Chim. Acta 199 (1991) 1-5
    • (1991) Clin. Chim. Acta , vol.199 , pp. 1-5
    • Weinreb, R.N.1    Jeng, S.2    Miller, A.L.3
  • 75
    • 33847045670 scopus 로고    scopus 로고
    • Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma
    • Yam G.H., Gaplovska-Kysela K., Zuber C., and Roth J. Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma. Am. J. Pathol. 170 (2007) 100-109
    • (2007) Am. J. Pathol. , vol.170 , pp. 100-109
    • Yam, G.H.1    Gaplovska-Kysela, K.2    Zuber, C.3    Roth, J.4
  • 76
    • 0023182904 scopus 로고
    • Lysosomal enzyme activities in cultured trabecular-meshwork cells
    • Yue B.Y., Elner V.M., Elner S.G., and Davis H.R. Lysosomal enzyme activities in cultured trabecular-meshwork cells. Exp. Eye Res. 44 (1987) 891-897
    • (1987) Exp. Eye Res. , vol.44 , pp. 891-897
    • Yue, B.Y.1    Elner, V.M.2    Elner, S.G.3    Davis, H.R.4
  • 77
    • 1542576499 scopus 로고    scopus 로고
    • Lipid peroxidation in the pathogenesis of primary open-angle glaucoma
    • Ziangirova G.G., and Antonova O.V. Lipid peroxidation in the pathogenesis of primary open-angle glaucoma. Vestn. Oftalmol. 119 (2003) 54-55
    • (2003) Vestn. Oftalmol. , vol.119 , pp. 54-55
    • Ziangirova, G.G.1    Antonova, O.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.