Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 6, 2008, Pages 2506-2511

  Fernández Durango, Raquel ^a   Fernández Martínez, Amalia ^a   García Feijoo, Julián ^a   Castillo, Alfredo ^a   De La Casa, José Martínez ^a   García Bueno, Borja ^b   Pérez Nievas, Beatriz G ^b   Fernández Cruz, Arturo ^a   Leza, Juan Carlos ^b  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ARGININE; CALCIUM ION; CITRULLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; NITRIC OXIDE SYNTHASE; THIOBARBITURIC ACID; 3-NITROTYROSINE; CALCIUM; DRUG DERIVATIVE; MESSENGER RNA; NOS2A PROTEIN, HUMAN; NOS3 PROTEIN, HUMAN; TYROSINE;

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; BIOTRANSFORMATION; CATARACT; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FILTERING OPERATION; HUMAN; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MAJOR CLINICAL STUDY; OPEN ANGLE GLAUCOMA; OXIDATIVE STRESS; PERIMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRABECULAR MESHWORK; TRABECULECTOMY; VISUAL FIELD; GENE EXPRESSION REGULATION; GENETICS; INTRAOCULAR PRESSURE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; UPREGULATION; VISUAL DISORDER;

AGED; AGED, 80 AND OVER; CALCIUM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; LIPID PEROXIDATION; MALONDIALDEHYDE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PERIMETRY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRABECULAR MESHWORK; TYROSINE; UP-REGULATION; VISION DISORDERS; VISUAL FIELDS;

EID: 47249102490     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1363     Document Type: Article

References (45)

1. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262-267. (Pubitemid 43325451)
2. Quigley HA. Open-angle glaucoma. N Engl J Med. 1993;328:1097-1106. (Pubitemid 23097800)
3. Bill A, Phillips CI. Uveoscleral drainage of aqueous humor in human eyes. Exp Eye Res. 1971;12:275-281.
4. Wiederholt M, Thieme H, Stumpff F. The regulation of trabecular meshwork and ciliary muscle contractility. Prog Retin Eye Res. 2000;19(3):271-295. (Pubitemid 30122724)
5. Tan JC, Peters DM, Kaufman P. Recent developments in understanding the pathophysiology of elevated intraocular pressure. Curr Opin Ophthalmol. 2006;17(2):168-174. (Pubitemid 43790813)
6. Alvarado JA, Murphy C, Juster, R. Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals. Ophthalmology. 1984;91:564-579. (Pubitemid 14120061)
7. Schmetterer L, Polak K. Role of nitric oxide in the control of ocular blood flow. Prog Retin Eye Res. 2001;20(6):823-847. (Pubitemid 32918287)
8. Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem. 1994;63:175-195. (Pubitemid 2109107)
9. Nathanson JA, McKee M. Identification of an extensive system of nitric oxide-producing cells in the ciliary muscle and outflow pathway of the human eye. Invest Ophthalmol Vis Sci. 1995;36:1765-1773.
10. Alvarado JA, Yeh RF, Franse-Carman L, Marcellino G, Brownstein MJ. Interactions between endothelia of the trabecular meshwork and of Schlemm's canal: a new insight into the regulation of aqueous outflow in the eye. Trans Am Ophthalmol Soc. 2005;103:148-162. (Pubitemid 43042110)
11. Schuman JS, Erickson K, Nathanson JA. Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys. Exp Eye Res. 1994;58:99-105. (Pubitemid 24071624)
12. Behar-Cohen FF, Goureau O, D'Hermies F, Courtois Y. Decreased intraocular pressure induced by nitric oxide donors is correlated to nitrite production in the rabbit eye. Invest Ophthalmol Vis Sci. 1996;37:1711-1715. (Pubitemid 26271425)
13. Chuman H, Chuman T, Nao-i N, Sawada A. The effect of L-arginine on intraocular pressure in the human eye. Curr Eye Res. 2000;20:511-516.
14. Schneemann A, Leusink-Muis A, van den Berg T, Hoyng PF, Kamphuis W. Elevation of nitric oxide production in human trabecular meshwork by increased pressure. Graefes Arch Clin Exp Ophthalmol. 2003;241(4):321-326. (Pubitemid 36748563)
15. Xue W, Du S, Li Y, Huan K. Pressure influence on mRNA expression and protein synthesis of inducible nitric oxide synthetase in bovine trabecular meshwork cell (in Chinese). Zhonghua Yan Ke Za Zhi. 2000;36(4):295-298.
16. Lipton SA, Choi YB, Pan ZH, et al. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 1993;364(6438):626-632. (Pubitemid 23274719)
17. Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys. 1991;288(2):481-487.
18. Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite oxidation of sulfhydryls: the cytotoxic potential of superoxide and nitric oxide. J Biol Chem. 1991;266(7):4244-4250. (Pubitemid 21909347)
19. Ischiropoulos H, Zhu L, Chen J, et al. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys. 1992;298(2):431-437.
20. Beckman JS, Chen J, Ischiropoulos H, Crow JP. Oxidative chemistry of peroxynitrite. Methods Enzymol. 1994;233:229-240. (Pubitemid 24177546)
21. Saccà SC, Pascotto A, Camicione P, Capris P, Izzotti A. Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma. Arch Ophthalmol. 2005;123:458-463. (Pubitemid 40489915)
22. Izzotti A, Saccà SC, Cartiglia C, De Flora S. Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients. Am J Med. 2003;114:638-646. (Pubitemid 36703232)
23. Lázaro García C, García Feijoo J, Castillo A, et al. Impact of intraocular pressure after filtration surgery on visual field progression in primary open-angle glaucoma. Eur J Ophthalmol. 2007;17:357-362. (Pubitemid 47056289)
24. Salter M, Knowles RG, Moncada. Widespread tissue distribution, species distribution and changes in activity of Ca(2+)-dependent and Ca(2+)-independent nitric oxide synthases. FEBS Lett. 1991;7:291(1):145-149.
25. Rees DD, Cunha FQ, Assreuy J, Herman AG, Moncada S. Sequential induction of nitric oxide synthase by Corynebacterium parvum in different organs of the mouse. Br J Pharmacol. 1995;114:689-693.
26. Das NP, Rutty AK. Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria. Biochem Med Metab Biol. 1987;37(2):258-264. (Pubitemid 17073829)
27. Rollin R, Mediero A, Roldan-Pallares M, Fernández-Cruz A, Fernández-Durango R. Natriuretic peptide system in the human retina. Mol Vis. 2004;10:15-22. (Pubitemid 38628982)
28. Beckman JS, Koppeno WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am J Physiol. 1996;271:C1424-C1437. (Pubitemid 26404872)
29. Nathanson JA, McKee M. Alterations of ocular nitric oxide synthase in human glaucoma. Invest Ophthalmol Vis Sci. 1995;36:1774-1784.
30. Tunny TJ, Richardson KA, Clark CV. Association study of the 5 flanking regions of endothelial-nitric oxide synthase and endothelin-1 genes in familial primary open-angle glaucoma. Clin Exp Pharmacol Physiol. 1998;25:26-29. (Pubitemid 28064503)
31. Logan JF, Chakravarthy U, Hughes AE, Patterson CC, Jackson JA, Rankin SJ. Evidence for association of endothelial nitric oxide synthase gene in subjects with glaucoma and a history of migraine. Invest Ophthalmol Vis Sci. 2005;46(9):3221-3226. (Pubitemid 44264308)
32. Uttenthal LO, Alonso D, Fernández AP, et al. Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat. Microsc Res Tech. 1998;43(1):75-88. (Pubitemid 28507016)
33. Xie Q-W, Kashiwabara Y, Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem. 1994;269:4705-4708. (Pubitemid 24239438)
34. Baldwin AS Jr. The NF-kappa B and I kappa-B proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-683. (Pubitemid 26130197)
35. Beverley PA, Buchwald VR. NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv Immunol. 1997;65:111-137. (Pubitemid 27323247)
36. Wang N, Chintala SK, Fini ME, Schuman JS. Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nat Med. 2001;7:304-309. (Pubitemid 32224345)
37. Motallebipour M, Rada-Iglesias A, Jansson M, Wadelius C. The promoter of inducible nitric oxide synthase implicated in glaucoma based on genetic analysis and nuclear factor binding. Mol Vis. 2005;11:950-957. (Pubitemid 41645672)
38. Ferreira SM, Lerner SF, Brunzini R, Evelson PA, Llesuy SF. Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol. 2004;137:62-69. (Pubitemid 38045188)
39. Braughler JM, Hall ED. Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation Free Radic Biol Med. 1989;6(3):289-301. (Pubitemid 19076495)
40. Hu ML, Shih MK. Ascorbic acid inhibits lipid peroxidation but enhances DNA damage in rat liver nuclei incubated with iron ions. Free Radic Res. 1997;26(6):585-592. (Pubitemid 27367945)
41. Gherghel D, Griffiths HR, Hilton EJ, et al. Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2005;46(3):877-883. (Pubitemid 41321023)
42. Babizhayev MA, Bunin AYa. Lipid peroxidation in open-angle glaucoma. Acta Ophthalmol (Copenh). 1989;67:371-377. (Pubitemid 19241433)
43. Liton PB, Luna C, Challa P, Epstein DL, Gonzalez P. Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue. Mol Vis. 2006;12:774-790. (Pubitemid 44044577)
44. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11(1):81-128. (Pubitemid 121003917)
45. Mattson MP. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci. 1998;21(2):53-57. (Pubitemid 28078902)