Multiple Gi proteins participate in nerve growth factor-induced activation of c-jun N-terminal kinases in PC12 cells

Neurochemical Research

Volumn 34, Issue 6, 2009, Pages 1101-1112

  Tso, Prudence H ^a   Morris, Christina J ^a   Yung, Lisa Y ^a   Ip, Nancy Y ^a   Wong, Yung H ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

C Jun N terminal kinase; Gi o proteins; Nerve growth factor; Neurite outgrowth; PC12 pheochromocytoma cells; Trk A receptor

Indexed keywords

INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; JANUS KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE GROWTH FACTOR; PERTUSSIS TOXIN; STRESS ACTIVATED PROTEIN KINASE; JAK3 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE A;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN PC12; CONTROLLED STUDY; MUTANT; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CELL STRAIN; CYTOLOGY; DRUG ANTAGONISM; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; JANUS KINASE 3; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; NERVE GROWTH FACTOR; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PC12 CELLS; PERTUSSIS TOXIN; PHOSPHORYLATION; RATS; RECEPTOR, TRKA; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 64249118273     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9880-9     Document Type: Article

References (75)

1. M Fukuda Y Gotoh T Tachibana 1995 Induction of neurite outgrowth by MAP kinase in PC12 cells Oncogene 11 239 244
2. Z Xia M Dickens J Raingeaud 1995 Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1326 1331 10.1126/science.270.5240.1326
3. V Waetzig T Herdegen 2003 The concerted signaling of ERK1/2 and JNKs is essential for PC12 cell neuritogenesis and converges at the level of target proteins Mol Cell Neurosci 24 238 249 10.1016/S1044-7431(03)00126-X
4. S Leppa R Saffrich W Ansorge 1998 Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation EMBO J 17 4404 4413 10.1093/emboj/17.15.4404
5. T Morooka E Nishida 1998 Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells J Biol Chem 273 24285 24288 10.1074/jbc.273.38.24285
6. SD Santos PJ Verveer PI Bastiaens 2007 Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate Nat Cell Biol 9 324 330 10.1038/ncb1543
7. M Deak AD Clifton LM Lucocq 1998 Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB EMBO J 17 4426 4441 10.1093/emboj/17.15.4426
8. A Eilers J Whitfield C Babij 1998 Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons J Neurosci 18 1713 1724
9. AC Maroney MA Glicksman AN Basma 1998 Motorneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway J Neurosci 18 104 111
10. YM Yu PL Han JK Lee 2003 JNK pathway is required for retinoic acid-induced neurite outgrowth of human neuroblastoma, SH-SY5Y NeuroReport 14 941 945 10.1097/00001756-200305230-00007
11. KS Park RD Lee SK Kang 2004 Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-γ via the JNK-dependent pathway Exp Cell Res 297 424 433 10.1016/j.yexcr.2004.03.034
12. SJ Kim TG Son K Kim 2007 Interferon-gamma promotes differentiation of neural progenitor cells via the JNK pathway Neurochem Res 32 1399 1406 10.1007/s11064-007-9323-z
13. M Eriksson M Taskinen S Leppa 2007 Mitogen activated protein kinase-dependent activation of c-Jun and c-Fos is required for neuronal differentiation but not for growth and stress response in PC12 cells J Cell Physiol 210 538 548 10.1002/jcp.20907
14. J Yamauchi Y Miyamoto M Murabe 2007 Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells Exp Cell Res 313 1886 1896 10.1016/j.yexcr.2007.02.019
15. DS Eom WS Choi S Ji 2005 Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells NeuroReport 16 823 828 10.1097/00001756-200505310-00009
16. Y Kita KD Kimura M Kobayashi 1998 Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway J Cell Sci 111 907 915
17. J Xiao Y Liu 2003 Differential roles of ERK and JNK in early and late stages of neuritogenesis: a study in a novel PC12 model system J Neurochem 86 1516 1523 10.1046/j.1471-4159.2003.01961.x
18. V Waetzig T Herdegen 2003 A single c-Jun N-terminal kinase isoform (JNK3-p54) is an effector in both neuronal differentiation and cell death J Biol Chem 278 567 572 10.1074/jbc.M207391200
19. o J Neurochem 54 1310 1320 10.1111/j.1471-4159.1990.tb01964.x
20. s isoforms in PC12 cells: relationship to neurite outgrowth Develop Brain Res 88 30 36 10.1016/0165-3806(95)00068-O
21. X Li SM Mumby A Greenwood 1995 Pertussis toxin-sensitive G protein α-subunits: production of monoclonal antibodies and detection of differential increases on differentiation of PC12 and LA-N-5 cells J Neurochem 64 1107 1117
22. o/i-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3 J Biol Chem 280 33426 33434 10.1074/jbc.M502812200
23. o/i signaling network in the regulation of neurite outgrowth Can J Physiol Pharmacol 84 687 694 10.1139/Y06-025
24. VL Lowes NY Ip YH Wong 2002 Integration of signals from receptor tyrosine kinases and G protein-coupled receptors Neurosignals 11 5 19 10.1159/000057317
25. AM Conway S Rakhit S Pyne 1999 Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase Biochem J 337 171 177 10.1042/0264-6021:3370171
26. S Rakhit S Pyne NJ Pyne 2000 The platelet-derived growth factor receptor stimulation of p42/p44 mitogen-activated protein kinase in airway smooth muscle involves a G-protein-mediated tyrosine phosphorylation of Gab1 Mol Pharmacol 58 413 420
27. i/o, G protein-coupled receptor kinase 2, β-arrestin 1, and endocytic processing Mol Pharmacol 60 63 70
28. i-coupled receptors Mol Pharmacol 52 38 45
29. M Kobayashi S Nagata Y Kita 1997 Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system J Biol Chem 272 16089 16092 10.1074/jbc.272.26.16089
30. M Ashcroft RM Stephens B Hallberg 1999 The selective and inducible activation of endogenous PI3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth Oncogene 18 4586 4597 10.1038/sj.onc.1202814
31. RD York DC Molliver SS Grewal 2000 Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1 Mol Cell Biol 20 8069 8083 10.1128/MCB.20.21.8069- 8083.2000
32. ES Coleman MW Wooten 1994 Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform J Mol Neurosci 5 39 57 10.1007/BF02736693
33. MW Wooten ML Vandenplas ML Seibenhener 2001 Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway Mol Cell Biol 21 8414 8427 10.1128/MCB.21.24.8414-8427.2001
34. YC Ma J Huang S Ali 2000 Src tyrosine kinase is a novel direct effector of G proteins Cell 102 635 646 10.1016/S0092-8674(00)00086-6
35. AS Chan FP Lai RK Lo 2002 Melatonin mt1 and MT2 receptors stimulate c-Jun N-terminal kinase via pertussis toxin-sensitive and -insensitive G proteins Cell Signal 14 249 257 10.1016/S0898-6568(01)00240-6
36. A Zapf-Colby J Eichhorn NJ Webster 1999 Inhibition of PLC-γ1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells Oncogene 18 4908 4919 10.1038/sj.onc.1202861
37. M Solem T [tmp] McMahon RO Messing 1995 Depolarization-induced neurite outgrowth in PC12 cells requires permissive, low level NGF receptor stimulation and activation of calcium/calmodulin-dependent protein kinase J Neurosci 15 5966 5975
38. H Nakayama T Numakawa T Ikeuchi 2001 Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells J Neurochem 79 489 498 10.1046/j.1471-4159.2001.00602.x
39. i signaling Oncogene 20 1615 1625 10.1038/sj.onc.1204190
40. i-family G-proteins: studies with pertussis toxin-resistant G-protein mutants Biochem J 321 721 728
41. i/o proteins Cell Signal 20 1538 1544 10.1016/j.cellsig.2008.04.007
42. A Piiper I Dikic MP Lutz 2002 Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells J Biol Chem 277 43623 43630 10.1074/jbc.M203926200
43. oα chain Mol Biol Cell 11 1129 1142
44. i2 mediates renal LLC-PK1 growth by a Raf-independent activation of p42/p44 MAP kinase Am J Physiol 72 F273 F282
45. H Lahlou N Saint-Laurent JP Esteve 2003 sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation J Biol Chem 278 39356 39371 10.1074/jbc.M304524200
46. q/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase J Biol Chem 273 22892 22898 10.1074/jbc.273.36.22892
47. LM Luttrell RJ Lefkowitz 2002 The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals J Cell Sci 115 455 465
48. AY Kam AS Chan YH Wong 2003 Rac and Cdc42-dependent regulation of c-Jun N-terminal kinases by the delta-opioid receptor J Neurochem 84 503 513 10.1046/j.1471-4159.2003.01535.x
49. M Hoshino S Nakamura 2003 Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells J Cell Biol 163 5 1067 1076 10.1083/jcb.200308070
50. J Troppmair JT Bruder H App 1992 Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol Oncogene 7 1867 1873
51. M Llovera Y de Pablo J Egea 2004 Trk is a calmodulin-binding protein: implications for receptor processing J Neurochem 88 422 433
52. 2+ and calmodulin Cell Signal 14 649 654 10.1016/S0898-6568(02) 00007-4
53. X Li RS Jope 1997 Glucocorticoids modulate G-protein α-subunit levels in PC12 cells Brain Res 759 213 220 10.1016/S0006-8993(97)00256-4
54. z attenuates Rap1-mediated differentiation of PC12 Cells J Biol Chem 277 43417 43424 10.1074/jbc. M204074200
55. T Uehara S Hoshino M Ui 1994 Possible involvement of phosphatidylinositol-specific phospholipase C related to pertussis toxin-sensitive GTP-binding proteins during adipocyte differentiation of 3T3-L1 fibroblasts: negative regulation of protein kinase C Biochim Biophys Acta 1224 302 310 10.1016/0167-4889(94)90204-6
56. i2 Science 258 1373 1375 10.1126/science.1455234
57. E Ogier-Denis A Petiot C Bauvy 1997 Control of the expression and activity of the Gα-interacting protein (GAIP) in human intestinal cells J Biol Chem 272 24599 24603 10.1074/jbc.272.39.24599
58. K Aoki T Nakamura M Matsuda 2004 Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells J Biol Chem 279 713 719 10.1074/jbc.M306382200
59. q-signaling cascade J Biol Chem 276 23362 23372 10.1074/jbc. M011752200
60. LM Luttrell E Kilgour J Larner 1990 A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes J Biol Chem 265 16873 16879
61. NA Moughal CM Waters WJ Valentine 2006 Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in PC12 cells J Neurochem 98 1920 1929 10.1111/j.1471-4159.2006.04009.x
62. i/o proteins are involved in nerve growth factor-induced pro-survival Akt signaling cascade in PC12 cells Cell Signal 17 881 890 10.1016/j.cellsig.2004.11.008
63. 4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells Cell Signal 18 285 293 10.1016/j.cellsig.2005.04.009
64. LM Luttrell T Van Biesen BE Hawes 1995 G subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor J Biol Chem 270 16495 16498 10.1074/jbc.270.28.16495
65. i with the insulin-like growth factor-I receptor. Release of G subunits upon receptor activation J Biol Chem 275 2255 2258 10.1074/jbc.275.4. 2255
66. RA Booth C Cummings M Tiberi 2002 GIPC participates in G protein signaling downstream of insulin-like growth factor 1 receptor J Biol Chem 277 6719 6725 10.1074/jbc.M108033200
67. X Lou H Yano F Lee 2001 GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways Mol Biol Cell 12 615 627
68. LH Wang RG Kalb SM Strittmatter 1999 A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF J Biol Chem 274 14137 14146 10.1074/jbc.274.20.14137
69. Z Liu TK Chatterjee RA Fisher 2002 RGS6 interacts with SCG10 and promotes neuronal differentiation Role of the Gγ subunit-like (GGL) domain of RGS6 J Biol Chem 277 37832 37839 10.1074/jbc.M205908200
70. F Alderton S Rakhit KC Kong 2001 Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells J Biol Chem 276 28578 28585 10.1074/jbc.M102771200
71. PH [tmp] McDonald C-W Chow WE Miller 2000 β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3 Science 290 1574 1577 10.1126/science.290.5496.1574
72. EHT Wu KKH Wu YH Wong 2007 Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors Neurosignals 15 217 227 10.1159/000101333
73. New DC, Wong YH (2007) Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression. J Mol Signal 2:2. doi: 10.1186/1750-2187-2-2
74. DC New KKH Wu AWS Kwok YH Wong 2007 G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis FEBS J 274 6025 6036 10.1111/j.1742-4658.2007.06116.x
75. A Patapoutian LF Reichardt 2001 Trk receptors: mediators of neurotrophin action Curr Opin Neurobiol 11 272 280 10.1016/S0959-4388(00)00208-7