Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells

NeuroReport

Volumn 16, Issue 8, 2005, Pages 823-828

  Eom, Dae Seok ^a   Choi, Won Seok ^a   Ji, Suena ^a   Cho, Jin W ^a   Oh, Young J ^a  

^a Yonsei University   (South Korea)

Author keywords

C Jun N terminal kinase; Dopaminergic neurons; Neurite outgrowth; Retinoic acid

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DOPAMINE; MITOGEN ACTIVATED PROTEIN KINASE P38; RETINOIC ACID; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; ENZYME ACTIVATION; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTHRACENES; BLOTTING, WESTERN; CELLS, CULTURED; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITORS; HYBRIDOMAS; IMMUNOHISTOCHEMISTRY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MESENCEPHALON; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURITES; NEURONS; RATS; TIME FACTORS; TRANSFECTION; TRETINOIN; TYROSINE 3-MONOOXYGENASE;

EID: 19544364886     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200505310-00009     Document Type: Article

References (24)

1. Harper SJ, LoGrasso P. Signalling for survival and death in neurons: the role of stress activated kinases, JNK and p38. Cell Signal 2001; 13: 299-310.
2. Thomas GM, Huganir RL. MAPK cascade signaling and synaptic plasticity. Nature Rev Neurosci 2004; 5:173-183.
3. Bodmer D, Gloddek B, Ryan AF, Huverstuhl J, Brors D. Inhibition of the c-Jun N-terminal kinase signaling pathway influences neurite outgrowth of spiral ganglion neurons in vitro. Laryngoscope 2002; 112: 2057-2061.
4. Huang C, Borchers CH, Schaller MD, Jacobson K. Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells. J Cell Biol 2004; 164:593-602.
5. Iwasaki S, Iguchi M, Watanabe K, Hoshino R, Tsujimoto M, Kohno M. Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2. J Biol Chem 1999; 274:26503-26510.
6. Morooka T, Nishida E. Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J Biol Chem 1998; 273:24285-24288.
7. Waetzig V, Herdegen T. The concerted signaling of ERK1/2 and JNKs is essential for PC12 cell neuritogenesis and converges at the target proteins. Mol Cell Neurosci 2003; 24:238-249.
8. Yao R, Yoshihara M, Osada H. Specific activation of a c-Jun NH2-terminal kinase isoform and induction of neurite outgrowth in PC-12 cells by staurosporine. J Biol Chem 1997; 272:18261-18266.
9. Yu YM, Han PL, Lee JK. JNK pathway is required for retinoic acid-induced neurite outgrowth of human neuroblastoma, SH-SY5Y Neuroreport 2003; 14:941-945.
10. Coffey ET, Hongisto V, Dickens M, Davis RJ, Courtney MJ. Dual roles for c-Jun N-terminal kinase in developmental and stress response in cerebellar granule neurons. J Neurosci 2000; 20:7602-7613.
11. Yoon S, Seger R, Choi EJ, Yoo YS. SB203580 induces prolonged B-Raf activation and promotes neuronal differentiation upon EGF treatment of PC12 cells. Biochemistry 2004; 69:799-805.
12. Choi WS, Chun SY, Markelonis GJ, Oh TH, Oh YJ. Overexpression of calbindin-D28K induces neurite outgrowth in dopaminergic neuronal cells via activation of p38 MAPK. Biochem Biophys Res Commun 2001; 287:656-661.
13. Eom DS, Choi WS, Oh YJ. Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase. Biochem Biophys Res Commun 2004; 314:377-381.
14. Choi HK, Won LA, Kontur PJ, Hammond DN, Fox AP, Wainer BH et al. Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion. Brain Res 1991; 552:67-76.
15. Choi HK, Won L, Roback JD, Wainer BH, Heller A. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. Proc Natl Acad Sci USA 1992; 89: 8943-8947.
16. Choi WS, Eom DS, Han BS, Kim WK, Han BH, Choi EJ et al. Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons. J Biol Chem 2004; 279:20451-20460.
17. Bennett BL, Sasaki DT, Murry BW, O'Leary EC, Sakata ST, Xu W et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 2001; 98:13681-13686.
18. Javelaud D, Laboureau J, Gabison E, Verrecchia F, Mauviel A. Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. J Biol Chem 2003; 278:24624-24628.
19. Han BS, Hong HS, Choi WS, Markelonis GJ, Oh TH, Oh YJ. Caspase-dependent and -independent cell death pathways in primary cultures of mesencephalic dopaminergic neurons after neurotoxin treatment. J Neurosci 2003; 23:5069-5078.
20. Xia XG, Harding T, Weller M, Bieneman A, Uney JB, Schulz JB. Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc Natl Acad Sci USA 2001; 98:10433-10438.
21. Xu P, Yoshioka K, Yoshimura D, Tominaga Y, Nishioka T, Ito M et al. In vitro development of mouse embryonic stem cells lacking JNK/stress-activated protein kinase-associated protein 1 (JSAP1) scaffold protein revealed its requirement during early embryonic neurogenesis. J Biol Chem 2003; 278:48422-48433.
22. Vaudry D, Stork PJ, Lazarovici P, Eiden LE. Signaling pathways for PC12 cell differentiation: making the right connections. Science 2002; 296: 1648-1649.
23. Xiao J, Liu Y. Different roles of ERK and JNK in early and late stages of neuritogenesis: a study in a novel PC12 model system. J Neurochem 2003; 86:1516-1523.
24. Chang L, Jones Y, Ellisman MH, Goldstein LS, Kari M. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell 2003; 4:521-533.