Nicotine attenuates iNOS expression and contributes to neuroprotection in a compressive model of spinal cord injury

Journal of Neuroscience Research

Volumn 87, Issue 4, 2009, Pages 937-947

  Lee, Mee Young ^a   Chen, Lei ^a   Toborek, Michal ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Inflammatory responses; Neuronal nicotinic receptors; Nicotine; Nitric oxide synthase; Oxidative stress; Spinal cord injury

Indexed keywords

3 NITROTYROSINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NEURON SPECIFIC NUCLEAR PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; NICOTINE; 3-NITROTYROSINE; AMINOGUANIDINE; DRUG DERIVATIVE; ENZYME INHIBITOR; GUANIDINE DERIVATIVE; NEUROPROTECTIVE AGENT; NOS2 PROTEIN, RAT; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG TARGETING; GENE CONTROL; LUMBAR SPINAL CORD; MALE; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD INJURY; THORACIC SPINAL CORD; UPREGULATION; ANIMAL; CYTOLOGY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; LONG EVANS RAT; METABOLISM; SPINAL CORD;

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GUANIDINES; INJECTIONS, INTRAPERITONEAL; MALE; MICROGLIA; NEUROPROTECTIVE AGENTS; NICOTINE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, LONG-EVANS; RNA, MESSENGER; SPINAL CORD; SPINAL CORD INJURIES; TYROSINE;

EID: 63849324148     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21901     Document Type: Article

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