4-Hydroxykobusin inhibits the induction of nitric oxide synthase by inhibiting NF-κB and AP-1 activation

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 6, 2007, Pages 1097-1101

  Pokharel, Yuba Raj ^a   Liu, Qing He ^a   Oh, Jae Wook ^a   Woo, Eun Rhan ^a   Kang, Keon Wook ^a  

^a Chosun University   (South Korea)

Author keywords

4 Hydroxykobusin; Activator protein 1 (AP 1); Geranium thunbergii; Inducible nitric oxide synthase (iNOS); Nitric oxide; Nuclear factor B (NF B)

Indexed keywords

4 HYDROXYKOBUSIN; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIGNAN DERIVATIVE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INDUCTION; GERANIUM; GERANIUM THUNBERGII; NONHUMAN; PROTEIN EXPRESSION; REPORTER GENE; TRANSACTIVATION;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; FORMAZANS; FURANS; GENES, REPORTER; GERANIUM; LIGNANS; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGES, PERITONEAL; MICE; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; TETRAZOLIUM SALTS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1;

EID: 34250007451     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1097     Document Type: Article

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