Nuclear quantum tunneling in the light-activated enzyme protochlorophyllide oxidoreductase

Journal of Biological Chemistry

Volumn 284, Issue 6, 2009, Pages 3762-3767

  Heyes, Derren J ^a   Sakuma, Michiyo ^a   de Visser, Sam P ^b   Scrutton, Nigel S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED ENZYMES; BREAKPOINT; CHLOROPHYLL BIOSYNTHESIS; DOUBLE BONDS; DYNAMIC SEARCH; ENZYME-SUBSTRATE COMPLEXES; FAST DYNAMICS; HYDRIDE ANIONS; HYDRIDE TRANSFER RATES; HYDRIDE TRANSFERS; PHOTO-REDUCTION; PHOTOEXCITED STATE; PHOTOSYNTHETIC APPARATUS; PROTEIN DYNAMICS; PROTOCHLOROPHYLLIDE; PROTOCHLOROPHYLLIDE OXIDOREDUCTASE; QUANTUM TUNNELING; TEMPERATURE DEPENDENCE; TIME-SCALE; TUNNELING REACTION;

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CHLOROPHYLL; ELECTRON TUNNELING; ENZYMES; HYDROGEN; PHOTOCHEMICAL REACTIONS; PORPHYRINS; PROTON TRANSFER; PROTONS;

TUNNELING (EXCAVATION);

CHLOROPHYLL; PROTOCHLOROPHYLLIDE; BACTERIAL PROTEIN; OXIDOREDUCTASE; PROTOCHLOROPHYLLIDE REDUCTASE; PROTON;

ARTICLE; CATALYSIS; DENSITY FUNCTIONAL THEORY; ENZYME SUBSTRATE COMPLEX; EXCITATION; LIGHT HARVESTING SYSTEM; PHOTOACTIVATION; PHOTOREACTIVITY; PHOTOSYNTHESIS; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTUM MECHANICS; TEMPERATURE DEPENDENCE; THERMODYNAMICS; TRANSPORT KINETICS; CHEMISTRY; CYANOBACTERIUM; ENZYMOLOGY; LIGHT; METABOLISM; OXIDATION REDUCTION REACTION; PHOTOCHEMISTRY;

BACTERIAL PROTEINS; CYANOBACTERIA; LIGHT; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PHOTOCHEMISTRY; PROTOCHLOROPHYLLIDE; PROTONS;

EID: 63649139679     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808548200     Document Type: Article

References (39)

1. Kohen, A., Cannio, R., Bartolucci, S., and Klinman, J. P. (1999) Nature 399, 496-499
2. Garcia-Viloca, M., Gao, J., Karplus, M., and Truhlar, D. G. (2004) Science 303, 186-195
3. Masgrau, L., Roujeinikova, A., Johannissen, L. O., Hothi, P., Basran, J., Ranaghan, K. E., Mulholland, A. J., Sutcliffe, M. J., Scrutton, N. S., and Leys, D. (2006) Science 312, 237-241
4. Benkovic, S. J., and Hammes-Schiffer, S. (2003) Science 301, 1196-1202
5. Benkovic, S. J., and Hammes-Schiffer, S. (2006) Science 312, 208-209
6. Boehr, D. D., McElheny, D., Dyson, H. J., and Wright, P. E. (2006) Science 313, 1638-1642
7. Heyes, D. J., and Hunter, C. N. (2005) Trends Biochem. Sci. 30, 642-649
8. Lebedev, N., and Timko, M. P. (1998) Photosyn. Res. 58, 5-23
9. Aronsson, H., Sundqvist, C., and Dahlin, C. (2003) Plant Mol. Biol. 51, 1-7
10. Bröcker, M. J., Virus, S., Ganskow, S., Heathcote, P., Heinz, D. W., Schubert, W. D., Jahn, D., and Moser, J. (2008) J. Biol. Chem. 283, 10559-10567
11. Heyes, D. J., Ruban, A. V., Wilks, H. M., and Hunter, C. N. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 11145-11150
12. Heyes, D. J., Heathcote, P., Rigby, S. E. J., Palacios, M. A., van Grondelle, R., and Hunter, C. N. (2006) J. Biol. Chem. 281, 26847-26853
13. Heyes, D. J., Ruban, A. V., and Hunter, C. N. (2003) Biochemistry 42, 523-528
14. Heyes, D. J., and Hunter, C. N. (2004) Biochemistry 43, 8265-8271
15. Heyes, D. J., Sakuma, M., and Scrutton, N. S. (2007) J. Biol. Chem. 282, 32015-32020
16. Begley, T. P., and Young, H. (1989) J. Am. Chem. Soc. 111, 3095-3096
17. Wilks, H. M., and Timko, M. P. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 724-728
18. Townley, H. E., Sessions, R. B., Clarke, A. R., Dafforn, T. R., and Griffiths, W. T. (2001) Proteins 44, 329-335
19. Heyes, D. J., Hunter, C. N., van Stokkum, I. H., van Grondelle, R., and Groot, M. L. (2003) Nat. Struct. Biol. 10, 491-492
20. Dietzek, B., Kiefer, W., Hermann, G., Popp, J., and Schmitt, M. (2006) J. Phys. Chem. B 110, 4399-4406
21. Zhao, G. J., and Han, K. L. (2008) Biophys. J. 94, 38-46
22. Sytina, O., Heyes, D. J., Hunter, C. N., Alexandre, M. T., van Stokkum, I. H. M., van Grondelle, R., and Groot, M. L. (2008) Nature 456, 1001-1004
23. Pudney, C. R., Hay, S., Sutcliffe, M. J., and Scrutton, N. S. (2006) J. Am. Chem. Soc. 128, 14053-14058
24. de Visser, S. P. (2006) J. Am. Chem. Soc. 128, 9813-9824
25. Becke, A. D. (1993) J. Chem. Phys. 98, 5648-5652
26. Hehre, W. J., Ditchfield, R., and Pople, J. (1972) J. Chem. Phys. 56, 2257-2261
27. Schrödinger LLC (2007) Jaguar 7.0, Schrödinger LLC., Portland, OR
28. Shaik, S., Kumar, D., de Visser, S. P., Altun, A., and Thiel, W. (2005) Chem. Rev. 105, 2279-2328
29. de Visser, S. P., Oh, K., Han, A.-R., and Nam, W. (2007) Inorg. Chem. 46, 4632-4641
30. Knapp, M. J., and Klinman, J. P. (2002) Eur. J. Biochem. 269, 3113-3121
31. Masgrau, L., Basran, J., Hothi, P., Sutcliffe, M. J., and Scrutton, N. S. (2004) Arch. Biochem. Biophys. 428, 41-51
32. Kuznetsov, A. M., and Ulstrup, J. (1999) Can. J. Chem. 77, 1085-1096
33. Knapp, M. J., Ricert, K., and Klinman, J. P. (2002) J. Am. Chem. Soc. 124, 3865-3874
34. Johannissen, L. O., Hay, S., Scrutton, N. S., and Sutcliffe, M. J. (2007) J. Phys. Chem. B 111, 2631-2638
35. Blomberg, L. M., Blomberg, M. R. A., and Siegbahn, P. E. M. (2004) J. Biol. Inorg. Chem. 9, 923-935
36. de Visser, S. P. (2006) Inorg. Chem. 45, 9551-9557
37. Frisch, M. J., Trucks, G. W., Schlegel, H. B., Scuseria, G. E., Robb, M. A., Cheeseman, J. R., Montgomery, J. A., Jr., Vreven, T., Kudin, K. N., Burant, J. C., Millam, J. M., Iyengar, S. S., Tomasi, J., Barone, V., Mennucci, B., Cossi, M., Scalmani, G., Rega N., Petersson, G. A., Nakatsuji, H., Hada, M., Ehara, M., Toyota, K., Fukuda, R., Hasegawa, J., Ishida, M., Nakajima, T., Honda, Y., Kitao, O., Nakai, N., Klene, M., Li, X., Knox, J. E., Hratchian, H. P., Cross, J. B., Adamo, C., Jaramillo, J., Gomperts, R., Stratmann, R. E., Yazyev, O., Austin, A. J., Cammi, R., Pomelli, C., Ochterski, J. W., Ayala, P. Y., Morokuma, K., Voth, G. A., Salvador, P., Dannenberg, J. J., Zakrzewski, V. G., Dapprich, S., Daniels, A. D., Strain, M. C., Farkas, O., Malick, D. K., Rabuck, A. D., Raghavachari, K., Foresman, J. B., Ortiz, J. V., Cui, Q., Baboul, A. G., Clifford, S., Cioslowski, J., Stefanov, B. B., Liu, G., Liashenko, A., Piskorz, P., Komaromi, I., Martin, R. L., Fox, D. J., Keith, T., Al-Laham, M. A., Peng, C. Y., Nanayakkara, A., Challacombe, M., Gill, P. M. W., Johnson, B., Chen, W., Wong, M. W., Gonzalez, C., and Pople, J. A. (2004) Gaussian-03, Revision C.01, Gaussian, Inc., Wallingford, CT
38. Basran, J., Sutcliffe, M. J., and Scrutton, N. S. (1999) Biochemistry 38, 3218-3222
39. Hammes-Schiffer, S., and Benkovic, S. J. (2006) Annu. Rev. Biochem. 75, 519-541