Perfluorooctane sulfonate (PFOS) toxicity in domestic chicken (Gallus gallus domesticus) embryos in the absence of effects on peroxisome proliferator activated receptor alpha (PPARα)-regulated genes

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 149, Issue 4, 2009, Pages 524-530

  O'Brien, Jason M ^a,b   Carew, Amanda C ^a,b   Chu, Shaogang ^b   Letcher, Robert J ^b   Kennedy, Sean W ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ENVIRONMENT CANADA   (Canada)

Author keywords

Chicken; Egg injection; Gene expression; Perfluorooctane sulfonate; Peroxisome proliferator; PFOS; PPAR

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; ACYL COENZYME A OXIDASE; FATTY ACID BINDING PROTEIN; PERFLUOROOCTANESULFONIC ACID; PEROXISOMAL 3 KETOACYL THIOLASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOTOXICITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AVES; GALLUS GALLUS; SPONDIAS PURPUREA;

EID: 63649092986     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2008.11.009     Document Type: Article

References (45)

1. Abbott, B.D., Wolf, C.J., Das, K.P., Zehr, R.D., Schmid, J.E., Lindstrom, A.B., Strynar, M.J., and Lau, C., Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPARalpha) in the mouse. Reprod. Toxicol. in press.
2. Chu S.G., and Letcher R.J. Analysis of fluorotelomer alcohols and perfluorinated sulfonamides in biotic samples by liquid chromatography-atmospheric pressure photoionization mass spectrometry. J. Chromatogr. A 1215 (2008) 92-99
3. Cwinn M.A., Jones S.P., and Kennedy S.W. Exposure to perfluorooctane sulfonate or fenofibrate causes PPAR-alpha dependent transcriptional responses in chicken embryo hepatocytes. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 148 (2008) 165-171
4. Diot C., and Douaire M. Characterization of a cDNA sequence encoding the peroxisome proliferator activated receptor alpha in the chicken. Poult. Sci. 78 (1999) 1198-1202
5. Feige J.N., Gelman L., Michalik L., Desvergne B., and Wahli W. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog. Lipid Res. 45 (2006) 120-159
6. Fuentes S., Colomina M.T., Rodriguez J., Vicens P., and Domingo J.L. Interactions in developmental toxicology: concurrent exposure to perfluorooctane sulfonate (PFOS) and stress in pregnant mice. Toxicol. Lett. 164 (2006) 81-89
7. Giesy J.P., and Kannan K. Global distribution of perfluorooctane sulfonate in wildlife. Environ. Sci. Technol. 35 (2001) 1339-1342
8. Guo Y., Jolly R.A., Halstead B.W., Baker T.K., Stutz J.P., Huffman M., Calley J.N., West A., Gao H., Searfoss G.H., Li S., Irizarry A.R., Qian H.R., Stevens J.L., and Ryan T.P. Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes. Toxicol. Sci. 96 (2007) 294-309
9. Hansen K.J., Clemen L.A., Ellefson M.E., and Johnson H.O. Compound-specific, quantitative characterization of organic: fluorochemicals in biological matrices. Environ. Sci. Technol. 35 (2001) 766-770
10. Heinz G.H., Hoffman D.J., Kondrad S.L., and Erwin C.A. Factors affecting the toxicity of methylmercury injected into eggs. Arch. Environ. Contam. Toxicol. 50 (2006) 264-279
11. Holmstrom K.E., Jarnberg U., and Bignert A. Temporal trends of PFOS and PFOA in guillemot eggs from the Baltic Sea, 1968-2003. Environ. Sci. Technol. 39 (2005) 80-84
12. Houde M., Martin J.W., Letcher R.J., Solomon K.R., and Muir D.C. Biological monitoring of polyfluoroalkyl substances: a review. Environ. Sci. Technol. 40 (2006) 3463-3473
13. Hu W., Jones P.D., Upham B.L., Trosko J.E., Lau C., and Giesy J.P. Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague-Dawley rats in vivo. Toxicol. Sci. 68 (2002) 429-436
14. Hu W., Jones P.D., DeCoen W., King L., Fraker P., Newsted J., and Giesy J.P. Alterations in cell membrane properties caused by perfluorinated compounds. Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 135 (2003) 77-88
15. Hundley S.G., Sarrif A.M., and Kennedy G.L. Absorption, distribution, and excretion of ammonium perfluorooctanoate (APFO) after oral administration to various species. Drug. Chem. Toxicol. 29 (2006) 137-145
16. Jones P.D., Hu W., De Coen W., Newsted J.L., and Giesy J.P. Binding of perfluorinated fatty acids to serum proteins. Environ. Toxicol. Chem. 22 (2003) 2639-2649
17. Kannan K., Franson J.C., Bowerman W.W., Hansen K.J., Jones P.D., and Giesy J.P. Perfluorooctane sulfonate in fish-eating water birds including bald eagles and albatrosses. Environ. Sci. Technol. 35 (2001) 3065-3070
18. Keller H., Devchand P.R., Perroud M., and Wahli W. PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents. Biol. Chem. 378 (1997) 651-655
19. Kissa E. Fluorinated Surfactants and Repellents. 2nd ed. (2001), Marcel Dekker, New York
20. Konig B., Kluge H., Haase K., Brandsch C., Stangl G.I., and Eder K. Effects of clofibrate treatment in laying hens. Poult. Sci. 86 (2007) 1187-1195
21. Lau C., Anitole K., Hodes C., Lai D., Pfahles-Hutchens A., and Seed J. Perfluoroalkyl acids: a review of monitoring and toxicological findings. Toxicol. Sci. 99 (2007) 366-394
22. Leubker D.J., Hansen K.J., Bass N.M., and Butenoff J.L. Interactions of fluorochemicals with rat liver fatty acid-binding protein. Toxicology 176 (2002) 175-185
23. Liu C., Du Y., and Zhou B. Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes. Aquat. Toxicol. 85 (2007) 267-277
24. Liu W., Chen S., Quan X., and Jin Y. Toxic effects of serial perfluorosulfonic and perfluorocarboxylic acids on the membrane system of a freshwater alga measured by flow cytometry. Environ. Toxicol. Chem. 27 (2008) 1597-1604
25. Luebker D.J., Hansen K.J., Bass N.M., Butenhoff J.L., and Seacat A.M. Interactions of fluorochemicals with rat liver fatty acid-binding protein. Toxicology 176 (2002) 175-185
26. Martin M.T., Brennan R.J., Hu W., Ayanoglu E., Lau C., Ren H., Wood C.R., Corton J.C., Kavlock R.J., and Dix D.J. Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity. Toxicol. Sci. 97 (2007) 595-613
27. McKernan M.A., Rattner B.A., Hale R.C., and Ottinger M.A. Egg incubation position affects toxicity of air cell administered polychlorinated biphenyl 126 (3,3′,4,4′,5-pentachlorobiphenyl) in chicken (Gallus gallus) embryos. Environ. Toxicol. Chem. 26 (2007) 2724-2727
28. Molina E.D., Balander R., Fitzgerald S.D., Giesy J.P., Kannan K., Mitchell R., and Bursian S.J. Effects of air cell injection of perfluorooctane sulfonate before incubation on development of the white leghorn chicken (Gallus domesticus) embryo. Environ. Toxicol. Chem. 25 (2006) 227-232
29. Mukherjee R., Jow L., Noonan D., and McDonnell D.P. Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J. Steroid Biochem. Mol. Biol. 51 (1994) 157-166
30. Nagasawa M., Ide T., Suzuki M., Tsunoda M., Akasaka Y., Okazaki T., Mochizuki T., and Murakami K. Pharmacological characterization of a human-specific peroxisome proliferater-activated receptor alpha (PPARalpha) agonist in dogs. Biochem. Pharmacol. 67 (2004) 2057-2069
31. Newsted J.L., Beach S.A., Gallagher S.P., and Giesy J.P. Pharmacokinetics and acute lethality of perfluorooctanesulfonate (PFOS) to juvenile mallard and northern bobwhite. Arch. Environ. Contam. Toxicol. 50 (2006) 411-420
32. Newsted J.L., Coady K.K., Beach S.A., Butenhoff J.L., Gallagher S., and Giesy J.P. Effects of perfluorooctane sulfonate on mallard and northern bobwhite quail exposed chronically via the diet. Environ. Toxicol. Pharmacol. 23 (2007) 1-9
33. Peraza M.A., Burdick A.D., Marin H.E., Gonzalez F.J., and Peters J.M. The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol. Sci. 90 (2006) 269-295
34. Seacat A.M., Thomford P.J., Hansen K.J., Olsen G.W., Case M.T., and Butenhoff J.L. Subchronic toxicity studies on perfluorooctanesulfonate potassium salt in cynomolgus monkeys. Toxicol. Sci. 68 (2002) 249-264
35. Seacat A.M., Thomford P.J., Hansen K.J., Clemen L.A., Eldridge S.R., Elcombe C.R., and Butenhoff J.L. Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats. Toxicology 183 (2003) 117-131
36. Senthil Kumar K. Fluorinated organic chemicals: a review. Res. J. Chem. Environ. 9 (2005) 50-79
37. Shi X., Du Y., Lam P.K., Wu R.S., and Zhou B. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicol. Appl. Pharmacol. 230 (2008) 23-32
38. Starkov A.A., and Wallace K.B. Structural determinants of fluorochemical-induced mitochondrial dysfunction. Toxicol. Sci. 66 (2002) 244-252
39. Taniyasu S., Kannan K., So M.K., Gulkowska A., Sinclair E., Okazawa T., and Yamashita N. Analysis of fluorotelomer alcohols, fluorotelorner acids, and short- and long-chain perfluorinated acids in water and biota. J. Chromatogr., A 1093 (2005) 89-97
40. Thibodeaux J.R., Hanson R.G., Rogers J.M., Grey B.E., Barbee B.D., Richards J.H., Butenhoff J.L., Stevenson L.A., and Lau C. Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations. Toxicol. Sci. 74 (2003) 369-381
41. Van den Heuvel J.P., Thompson J.T., Frame S.R., and Gillies P.J. Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. Toxicol. Sci. 92 (2006) 476-489
42. Verreault J., Houde M., Gabrielsen G.W., Berger U., Haukas M., Letcher R.J., and Muir D.C. Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus) from the Norwegian arctic. Environ. Sci. Technol. 39 (2005) 7439-7445
43. Xu L., Krenitsky D.M., Seacat A.M., Butenhoff J.L., and Anders M.W. Biotransformation of N-ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450. Chem. Res. Toxicol. 17 (2004) 767-775
44. Yang Q., Xie Y., Alexson S.E., Nelson B.D., and DePierre J.W. Involvement of the peroxisome proliferator-activated receptor alpha in the immunomodulation caused by peroxisome proliferators in mice. Biochem. Pharmacol. 63 (2002) 1893-1900
45. Yeung L.W., Guruge K.S., Yamanaka N., Miyazaki S., and Lam P.K. Differential expression of chicken hepatic genes responsive to PFOA and PFOS. Toxicology 237 (2007) 111-125