Pharmacological characterization of a human-specific peroxisome proliferater-activated receptor α (PPARα) agonist in dogs

Biochemical Pharmacology

Volumn 67, Issue 11, 2004, Pages 2057-2069

  Nagasawa, Michiaki ^a   Ide, Tomohiro ^a   Suzuki, Masahiro ^a   Tsunoda, Masaki ^a   Akasaka, Yunike ^a   Okazaki, Takashi ^a   Mochizuki, Toshiro ^a   Murakami, Koji ^a  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

acyl CoA oxidase; AOX; Chinese hamster ovary K1; CHO K1; DMEM; Dulbecco's modified Eagle's medium; KCL; KCL 1999000269; LBD; ligand binding domain; peroxisome proliferator activated receptor; peroxisome proliferator response element; PPAR; PPRE; RACE

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; KCL 1999000269; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PIRINIXIC ACID; TRANSCRIPTION FACTOR GAL4; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; CHIMERA; CHO CELL; CONTROLLED STUDY; DOG; DRUG POTENCY; LIGAND BINDING; LIVER CELL; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SPECIES DIFFERENCE; TRANSACTIVATION; TRIACYLGLYCEROL BLOOD LEVEL;

AMINO ACID SEQUENCE; ANIMALS; ANTILIPEMIC AGENTS; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DOGS; FEMALE; GENE EXPRESSION; HEPATOCYTES; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; POTASSIUM CHLORIDE; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 2342475664     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.02.019     Document Type: Article

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