Interactions of flurochemicals with rat liver fatty acid-binding protein

Toxicology

Volumn 176, Issue 3, 2002, Pages 175-185

  Luebker, Deanna J ^a   Hansen, Kris J ^a   Bass, Nathan M ^b   Butenhoff, John L ^a   Seacat, Andrew M ^a  

^a 3M COMPANY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Liver fatty acid binding protein; N ethylperfluorooctanesulfonamide; N ethylperfluorooctanesulfonamido ethanol; Perfluorooctanesulfonate; Perfluorooctanoate; Relative dissociation constants

Indexed keywords

11 (5 DIMETHYLAMINONAPHTHALENESULFONYL)UNDECANOIC ACID; ALCOHOL; FATTY ACID; FATTY ACID BINDING PROTEIN; LIGAND; N ETHYLPERFLUOROOCTANESULFONAMIDOETHANOL; PERFLUOROOCTANE; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; UNDECANOIC ACID; CARRIER PROTEIN; FABP1 PROTEIN, MOUSE; FABP1 PROTEIN, RAT; FABP7 PROTEIN, RAT; FLUORESCENT DYE; FLUOROCARBON; NERVE PROTEIN; PIRINIXIC ACID; PYRIMIDINE DERIVATIVE; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISSOCIATION CONSTANT; IC 50; IN VITRO STUDY; LIVER; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; RAT; RODENT; ALGORITHM; ANIMAL; BINDING COMPETITION; CHEMISTRY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; SPECTROFLUOROMETRY;

RODENTIA;

ALGORITHMS; ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FATTY ACID-BINDING PROTEINS; FATTY ACIDS; FLUORESCENT DYES; FLUOROCARBONS; LIVER; MALE; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PEROXISOME PROLIFERATORS; PROTEIN BINDING; PYRIMIDINES; RATS; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0037098862     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00081-1     Document Type: Article

References (40)

1. Possible involvement of fatty acid binding protein in peroxisomal β-oxidation of fatty acids
2. Physiology and molecular biology of hepatic cytosolic fatty acid-binding protein
3. Alkylthioacetic acid (3-thia fatty acids) - A new group of non-β-oxidizable, peroxisome-inducing fatty acid analogues. I. A study on the structural requirements for proliferation of peroxisomes and mitochondria in rat liver
4. Effects of ammonium perfluorooctanoate on Leydig cell function: In vitro, in vivo, and ex vivo studies
5. Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal β-oxidation
6. Comparative sub-chronic toxicity of perfluorooctane sulfonate (PFOS) and N-ethyl perfluoroctanesulfonamidoethanol (N-EtFOSE) in the rat
7. Interaction of LY171883 and other peroxisome proliferators with fatty-acid-binding protein isolated from rat liver
8. Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans
9. Peroxisome proliferator-activated receptors: Nuclear control of metabolism
10. Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): Species differences and possible mechanisms
11. Phytanic acid activates the peroxisome proliferator-activated receptor α (PPARα) in sterol carrier protein 2-/ sterol carrier protein x-deficient mice
12. The nucleotide sequence of rat liver fatty acid binding protein mRNA
13. The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid
14. The induction of peroxisome proliferation in rat liver by perfluorinated fatty acids, metabolically inert derivatives of fatty acids
15. Induction of cytochrome P-450 and peroxisome proliferation in rat liver by perfluorinated octanesulfonic acid
16. A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation
17. Purification and characterization of a fatty-acid-binding protein from the gastric mucosa of rats. Possible identity with heart fatty-acid-binding protein and its parietal cell localization
18. Effects of peroxisome proliferators on fatty acid-binding protein in rat liver
19. Increase in mouse liver weight following feeding of ammonium perfluorooctanote and related fluorochemicals
20. Repeated dose toxicity of fluorinated acids in rats
21. Roles of PPARs in health and disease
22. Species differences in hepatic peroxisome proliferation
23. Trans-activation of PPARα and PPARγ by structurally diverse environmental chemicals
24. Investigation of the no observable effect level for perfluorooctane sulfonate in cynomolgus monkeys after 26 weeks of oral dosing and 1 year of recovery
25. Studies on fatty acid-binding proteins. Changes in the concentration of hepatic fatty acid-binding protein during development in the rat
26. Perfluorooctane sulfonic acid is a potent inducer of peroxisomal fatty acid β-oxidation and other activities known to be affected by peroxisome proliferators in mouse liver
27. The crystal structure of the liver fatty acid-binding protein. A complex with two bound oleates
28. Characterization of binding and structural properties of rat liver fatty-acid-binding protein using tryptophan mutants
29. The binding of natural and fluorescent lysophospholipids to wild-type and mutant rat liver fatty acid-binding protein and albumin
30. The binding of cholesterol and bile salts to recombinant rat liver fatty acid-binding protein
31. Effect on ligand binding of arginine mutations in recombinant rat liver fatty acid-binding protein
32. The binding of lysophospholipids to rat liver fatty acid-binding protein and albumin
33. Mutations of recombinant rat liver fatty acid-binding protein at residues 102 and 122 alter its structural integrity and affinity for physiological ligands
34. Early modulation of genes encoding peroxisomal and mitochondrial β-oxidation enzymes by 3-thia fatty acids
35. Perfluorodecanoic acid as a useful pharmacologic tool for the study of peroxisome proliferation
36. Studies on fatty acid-binding proteins. The detection and quantification of the protein from rat liver by using a fluorescent fatty acid analogue
37. Relation of equilibrium contact angle to liquid and solid constitution