Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague-Dawley rats in vivo

Toxicological Sciences

Volumn 68, Issue 2, 2002, Pages 429-436

  Hu, Wenyue ^a   Jones, Paul D ^a   Upham, Brad L ^b   Trosko, James E ^b   Lau, Christopher ^c   Giesy, John P ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

GJIC; Perfluorinated chemicals; PFOS; QSAR; Rodents

Indexed keywords

ALKANE DERIVATIVE; ORGANIC COMPOUND; PERFLUORO COMPOUND; PERFLUOROOCTANE; SULFONAMIDE; SULFONIC ACID DERIVATIVE; ALKANESULFONIC ACID; FLUOROCARBON; PERFLUOROOCTANE SULFONIC ACID; PERFLUOROOCTANESULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COMMUNICATION; CELL FUNCTION; CELL GROWTH; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; EPITHELIUM CELL; FEMALE; GAP JUNCTION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; LIVER CELL; MALE; NONHUMAN; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION; TECHNIQUE; TISSUE SPECIFICITY; ANIMAL; CELL JUNCTION; CHEMISTRY; DRUG EFFECT; KIDNEY; LIVER; PERCIFORMES; PHYSIOLOGY; POLLUTANT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SPRAGUE DAWLEY RAT;

ALKANESULFONIC ACIDS; ANIMAL; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EPITHELIAL CELLS; FEMALE; FLUOROCARBONS; GAP JUNCTIONS; KIDNEY; LIVER; MALE; PERCIFORMES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS;

ANIMALIA; RODENTIA;

EID: 0036667363     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/68.2.429     Document Type: Article

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