Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine

Brain Research

Volumn 1264, Issue , 2009, Pages 85-97

  Fei, Xi Feng ^a,c   Qin, Zheng Hong ^a   Xiang, Bei ^a   Li, Ling Yun ^a   Han, Feng ^b   Fukunaga, Kohji ^b   Liang, Zhong Qin ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b TOHOKU UNIVERSITY   (Japan)

^c THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Cathepsin L; Cell cycle; Cyclin; Dopaminergic neuron; LC3; Parkinson's disease

Indexed keywords

CATHEPSIN L; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; OLOMOUCINE; OXIDOPAMINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CUX; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CELL CYCLE PROGRESSION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME KINETICS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INTRACELLULAR TRANSPORT; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA;

ANALYSIS OF VARIANCE; ANIMALS; AUTOPHAGY; CATHEPSINS; CELL COUNT; CELL CYCLE; CELL DEATH; CELLS, CULTURED; CYCLIN B; CYCLIN D1; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; KINETIN; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE; UP-REGULATION;

RATTUS;

EID: 63449106096     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.01.057     Document Type: Article

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