Gα13 regulates methacholine-induced contraction of bronchial smooth muscle via phosphorylation of MLC20

Biochemical Pharmacology

Volumn 77, Issue 9, 2009, Pages 1497-1505

  Lee, Song Jin ^a,b   Lee, Woo Hyung ^a   Ki, Sung Hwan ^a   Kim, Young Mi ^a   Lee, Seung Jin ^a,c   Lee, Chang Ho ^d   Kim, Sang Geon ^a  

^a Tumor Microenvironment Global Core Research Center   (South Korea)

^b Yuhan Corporation   (South Korea)

^c Asan Medical Center   (South Korea)

^d Department of Biochemistry and Molecular Biology   (South Korea)

Author keywords

Bronchiolar smooth muscle; G 12 family; G 13; Methacholine; MLC20

Indexed keywords

ACTIN; METHACHOLINE; MYOSIN; MYOSIN LIGHT CHAIN 2; OVALBUMIN; SMALL INTERFERING RNA; BRONCHOCONSTRICTING AGENT; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; METHACHOLINE CHLORIDE; MYOSIN LIGHT CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; BRONCHUS; BRONCHUS MUSCLE; CONTROLLED STUDY; EMBRYO; GALPHA12 GENE; GALPHA13 GENE; GENE; LUNG PARENCHYMA; MICROSCOPY; MOUSE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; TRACHEA; TRACHEA MUSCLE; AIRWAY RESISTANCE; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY;

AIRWAY RESISTANCE; ANIMALS; BRONCHI; BRONCHOCONSTRICTOR AGENTS; CALCIUM; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; METHACHOLINE CHLORIDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOSIN LIGHT CHAINS; OVALBUMIN; PHOSPHORYLATION; RESPIRATORY HYPERSENSITIVITY; TRACHEA;

EID: 63449088090     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.01.016     Document Type: Article

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