Increased expression of G12 and G13 proteins in bronchial smooth muscle of airway hyperresponsive rats

Inflammation Research

Volumn 50, Issue 6, 2001, Pages 333-336

  Chiba, Y ^a   Misawa, M ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Airway hyperresponsiveness; Bronchial smooth muscle; Ca2+ sensitization; G12 protein; G13 protein

Indexed keywords

BETA ACTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; RHO FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; BRONCHUS MUSCLE; CONTROLLED STUDY; IMMUNOBLOTTING; MALE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SENSITIZATION; SMOOTH MUSCLE CONTRACTION; ANIMAL; BIOSYNTHESIS; BRONCHUS; METABOLISM; SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; BRONCHI; BRONCHIAL HYPERREACTIVITY; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HETEROTRIMERIC GTP-BINDING PROTEINS; MALE; MUSCLE, SMOOTH; RATS; RATS, WISTAR;

EID: 0034743534     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000253     Document Type: Article

References (27)

1. 2+ and contraction induced by various stimulants and relaxants in canine tracheal smooth muscle
2. 2+ sensitization of bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats
3. Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator Fura 2
4. 2+ sensitization of skinned muscle of guinea pig vas deferens
5. Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle
6. Role of Rho proteins in carbacol-induced contractions in intact and permeabilized guiena-pig intestinal smooth muscle
7. 2+ sensitization of smooth muscle
8. Comparison of in-vivo responsiveness and in-vitro smooth muscle sensitivity to methacholine
9. Repeated antigenic challenge-induced airway hyperresponsiveness and airway inflammation in actively sensitized rats
10. Characteristics of muscarinic cholinoceptors in airways of antigen-induced airway hyperresponsive rats
11. 2+ availability involved in antigen-induced airway hyperresponsiveness in rats
12. 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
13. 13 activates a phospholipase D isoenzyme by a pathway requiring Rho family GTPases
14. 13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets
15. Protein measurement with the folin phenol reagent
16. 2+ sensitization
17. 2+ sensitization through inhibition of myosin phosphatase in rabbit trachea
18. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-smooth muscle myosin II
19. Cellular redistribution of PKCα, rhoA, and ROCα following smooth muscle agonist stimulation
20. 13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate
21. 13
22. q protein level increases concurrently with antigen-induced airway hyperresponsiveness in rats
23. i-2 activation of Rho
24. 2+ sensitization of tracheal smooth muscle
25. 13 in receptor-mediated stress fiber formation
26. 13
27. 13 in agonist-induced vascular smooth muscle cell contraction