Leukotriene B4 stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis

Journal of Biological Chemistry

Volumn 277, Issue 10, 2002, Pages 8572-8578

  Woo, Chang Hoon ^a   You, Hye Jin ^a,b   Cho, Sung Hoon ^a,b   Eom, Young Woo ^a   Chun, Jang Soo ^b   Yoo, Yung Joon ^b   Kim, Jae Hong ^a  

^a Korea University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; DNA; ENZYMES; IMMUNOLOGY; MUTAGENESIS; ORGANIC ACIDS; OXYGEN;

CHEMOTAXIS;

BIOCHEMICAL ENGINEERING;

ARACHIDONIC ACID; CHEMOATTRACTANT; LEUKOTRIENE B4; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PHOSPHOLIPASE A2; RAC PROTEIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ARACHIDONIC ACID; CELL DIVISION; CELLS, CULTURED; CHEMOTAXIS; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FIBROBLASTS; GENES, DOMINANT; HYDROGEN PEROXIDE; IMMUNOBLOTTING; LEUKOTRIENE B4; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A; PLASMIDS; PROTEIN BINDING; PROTEIN TRANSPORT; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0037040973     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104766200     Document Type: Article

References (42)