Therapeutic effect of low-dose IL-18 combined with IL-10 on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of Th2 responses

Rheumatology International

Volumn 29, Issue 6, 2009, Pages 615-622

  Dai, Qiaomei ^a,b   Li, Yang ^a   Zhang, Fengshan ^a   Yu, Haiyue ^a   Wang, Xiaoyan ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Collagen induced arthritis; Interleukin 10; Interleukin 18; Th2 responses

Indexed keywords

COLLAGEN TYPE 2; INTERLEUKIN 18 RECEPTOR ALPHA; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 12; RECOMBINANT INTERLEUKIN 18; RECOMBINANT INTERLEUKIN 4; TRANSCRIPTION FACTOR GATA 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; IMMUNE RESPONSE; IMMUNOMODULATION; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH2 CELL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; COLLAGEN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG THERAPY, COMBINATION; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-18; MALE; MICE; MICE, INBRED DBA; RECOMBINANT PROTEINS; TH1 CELLS; TH2 CELLS;

EID: 63349106991     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-008-0732-3     Document Type: Article

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