Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer

Journal of Clinical Oncology

Volumn 27, Issue 10, 2009, Pages 1549-1556

  Klein, Christoph A ^a   Weckermann, Dorothea ^a   Polzer, Bernhard ^a   Ragg, Thomas ^a   Blana, Andreas ^a   Schlimok, Günter ^a   Arnholdt, Hans ^a   Bertz, Simone ^a   Harzmann, Rolf ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 8; MONOCLONAL ANTIBODY;

AGED; ARTICLE; BONE MARROW BIOPSY; BONE MARROW METASTASIS; CANCER DIAGNOSIS; CANCER INVASION; CANCER RELAPSE; CANCER RISK; CANCER STAGING; CELL FATE; CELL ISOLATION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; GENETIC ANALYSIS; GENOTYPE; HIGH RISK PATIENT; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PREVALENCE; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATECTOMY; RISK ASSESSMENT; TUMOR CELL;

BONE MARROW NEOPLASMS; COMPARATIVE GENOMIC HYBRIDIZATION; HUMANS; KAPLAN-MEIERS ESTIMATE; KERATINS; MALE; NEOPLASM METASTASIS; PROGNOSIS; PROSTATECTOMY; PROSTATIC NEOPLASMS; RISK FACTORS; TIME;

EID: 63749083366     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2008.17.0563     Document Type: Article

References (19)

1. Husemann Y, Geigl JB, Schubert F, et al: Systemic spread is an early step in breast cancer. Cancer Cell 13:58-68, 2008
2. Bill-Axelson A, Holmberg L, Ruutu M, et al: Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med 352:1977-1984, 2005
3. Klein CA: The systemic progression of human cancer: A focus on the individual disseminated cancer cell - the unit of selection. Adv Cancer Res 89:35-67, 2003
4. Braun S, Pantel K, Muller P, et al: Cytokeratin- positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med 342:525-533, 2000
5. Pantel K, Cote RJ, Fodstad O: Detection and clinical importance of micrometastatic disease. J Natl Cancer Inst 91:1113-1124, 1999
6. Bianco FJ Jr, Wood DP Jr, Gomes de Oliveira J, et al: Proliferation of prostate cancer cells in the bone marrow predicts recurrence in patients with localized prostate cancer. Prostate 49:235-242, 2001
7. Weckermann D, Muller P, Wawroschek F, et al: Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: Detection and prognostic value. J Urol 166:699-703, 2001
8. Braun S, Vogl FD, Naume B, et al: A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med 353:793-802, 2005
9. Stoecklein NH, Hosch SB, Bezler M, et al: Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. Cancer Cell 13:441453, 2008
10. Janni W, Rack B, Schindlbeck C, et al: The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence. Cancer 103:884-891, 2005
11. Baudis M, Cleary ML: Progenetix.net: An online repository for molecular cytogenetic aberration data. Bioinformatics 17:1228-1229, 2001
12. Klein CA, Blankenstein TJ, Schmidt-Kittler O, et al: Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 360:683-689, 2002
13. Holcomb IN, Grove DI, Kinnunen M, et al: Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients. Cancer Res 68:5599-5608, 2008
14. Kaplan RN, Riba RD, Zacharoulis S, et al: VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438:820-827, 2005
15. McAllister SS, Gifford AM, Greiner AL, et al: Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell 133:994-1005, 2008
16. Taniguchi T, Toi M, Inada K, et al: Serum concentrations of hepatocyte growth factor in breast cancer patients. Clin Cancer Res 1:1031-1034, 1995
17. Baum M, Demicheli R, Hrushesky W, et al: Does surgery unfavourably perturb the "natural history" of early breast cancer by accelerating the appearance of distant metastases? Eur J Cancer 41:508-515, 2005
18. Fisher B, Gunduz N, Coyle J, et al: Presence of a growth-stimulating factor in serum following primary tumor removal in mice. Cancer Res 49:1996-2001, 1989
19. Retsky M, Bonadonna G, Demicheli R, et al: Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer pa-tients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients. Breast Cancer Res 6:R372-R374, 2004 20. Hachiya T, Ichinose T, Hirakata H, et al: Prostate-specific antigen failure within 2 years of radical prostatectomy predicts overall survival. Int J Urol 13:362-367, 2006