메뉴 건너뛰기




Volumn 21, Issue 2, 2009, Pages 351-355

Clinical significance of Smac/DIABLO expression in colorectal cancer

Author keywords

Colorectal cancer; Immunohistochemistry; Prognosis; Smac DIABLO

Indexed keywords

SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; DIABLO PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; SIGNAL PEPTIDE; TUMOR MARKER;

EID: 62849124148     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000229     Document Type: Article
Times cited : (44)

References (40)
  • 1
    • 33746895175 scopus 로고    scopus 로고
    • Mitochondria as therapeutic target for cancer chemotherapy
    • Galluzzi L, Larochette N, Zamzani N and Kroemer G: Mitochondria as therapeutic target for cancer chemotherapy. Oncogene 25: 4812-4830, 2006.
    • (2006) Oncogene , vol.25 , pp. 4812-4830
    • Galluzzi, L.1    Larochette, N.2    Zamzani, N.3    Kroemer, G.4
  • 2
    • 0032806596 scopus 로고    scopus 로고
    • Apoptosis: Checkpoint at the mitomchondrial frontier
    • Bossy-Wetzel E and Green DR: Apoptosis: checkpoint at the mitomchondrial frontier. Mutat Res 434: 243-251, 1999.
    • (1999) Mutat Res , vol.434 , pp. 243-251
    • Bossy-Wetzel, E.1    Green, D.R.2
  • 3
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kromer G and Reed JC: Mitochondrial control of cell death. Nat Med 6: 513-519, 2000.
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kromer, G.1    Reed, J.C.2
  • 4
    • 0005632286 scopus 로고    scopus 로고
    • A lively meeting of a deathly topic
    • Kluck RM and Kashibatta S: A lively meeting of a deathly topic. Apoptosis 2: 337-342, 1997.
    • (1997) Apoptosis , vol.2 , pp. 337-342
    • Kluck, R.M.1    Kashibatta, S.2
  • 5
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2-Release of cytochrome-c from the mitochondria blocked
    • Yang J, Liu X, Balla K, Gillenwiter A, et al: Prevention of apoptosis by Bcl-2-Release of cytochrome-c from the mitochondria blocked. Science 275: 1129-1136, 1997.
    • (1997) Science , vol.275 , pp. 1129-1136
    • Yang, J.1    Liu, X.2    Balla, K.3    Gillenwiter, A.4
  • 6
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • Susin SA, Zamazami N, Castedo M, et al: Bcl-2 inhibits the mitochondrial release of an apoptogenic protease J Exp Med 184: 1331-1341, 1996.
    • (1996) J Exp Med , vol.184 , pp. 1331-1341
    • Susin, S.A.1    Zamazami, N.2    Castedo, M.3
  • 7
    • 0035811511 scopus 로고    scopus 로고
    • Mitochondrial endonuclease G is important for apoptosis in C. elegans
    • Parrish L, Li K, Klotz D, et al: Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature 412: 90-94, 2001.
    • (2001) Nature , vol.412 , pp. 90-94
    • Parrish, L.1    Li, K.2    Klotz, D.3
  • 8
    • 18544386724 scopus 로고    scopus 로고
    • Idetification of Omi/ HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
    • Hedge R, Srinivasula SM, Zhang Z, et al: Idetification of Omi/ HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. J Biol Chem 277: 432-438, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 432-438
    • Hedge, R.1    Srinivasula, S.M.2    Zhang, Z.3
  • 9
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA and Lazebnik Y: Caspases: enemies within. Science 281: 1312-1316, 1998.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 11
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins - suppressors of apoptosis
    • Deveraux QL and Reed JC: IAP family proteins - suppressors of apoptosis. Genes Dev 13: 239-252, 1999.
    • (1999) Genes Dev , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 12
    • 17144438370 scopus 로고    scopus 로고
    • Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
    • Tamm I, Kornblau SM, Segall H, et al: Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. Clin Cancer Res 6: 1796-1803, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 1796-1803
    • Tamm, I.1    Kornblau, S.M.2    Segall, H.3
  • 13
    • 10744232728 scopus 로고    scopus 로고
    • Elevated expression of inhibitor of apoptosis proteins in prostate cancer
    • Krajewska M, Krajewski S, Banares S, et al: Elevated expression of inhibitor of apoptosis proteins in prostate cancer. Clin Cancer Res 9: 4914-4925, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 4914-4925
    • Krajewska, M.1    Krajewski, S.2    Banares, S.3
  • 14
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L and Wang X: Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42, 2000.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 15
    • 0034616942 scopus 로고    scopus 로고
    • Idetification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
    • Verhagen AM, Ekert PG, Pakusch J, et al: Idetification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102: 43-53, 2000.
    • (2000) Cell , vol.102 , pp. 43-53
    • Verhagen, A.M.1    Ekert, P.G.2    Pakusch, J.3
  • 16
    • 0034700491 scopus 로고    scopus 로고
    • Structual basis of IAP recognition by Smac/DIABLO
    • Wu G, Chai J, Suber TL, et al: Structual basis of IAP recognition by Smac/DIABLO. Nature 408: 1008-1012, 2000.
    • (2000) Nature , vol.408 , pp. 1008-1012
    • Wu, G.1    Chai, J.2    Suber, T.L.3
  • 17
    • 34548827057 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria
    • Van Ginkel PR, Sareen D, Subramanian L, et al: Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria. Clin Cancer Res 13: 5162-5169, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 5162-5169
    • Van Ginkel, P.R.1    Sareen, D.2    Subramanian, L.3
  • 18
    • 34447308516 scopus 로고    scopus 로고
    • Potentiation of antileukemic therapies by Smac mimetics, LBW242: Effects on mutant FLT3-expreaaing cells
    • Weisberg E, Kung AL, Wright RD, et al: Potentiation of antileukemic therapies by Smac mimetics, LBW242: effects on mutant FLT3-expreaaing cells. Mol Cancer Ther 6: 1951-1961, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1951-1961
    • Weisberg, E.1    Kung, A.L.2    Wright, R.D.3
  • 19
    • 13144251279 scopus 로고    scopus 로고
    • Expression of Smac/DIABLO is a novel prognostic marker in lung cancer
    • Sekimura A, Konishi A, Mizuno K, et al: Expression of Smac/DIABLO is a novel prognostic marker in lung cancer. Oncol Rep 11: 797-802, 2004.
    • (2004) Oncol Rep , vol.11 , pp. 797-802
    • Sekimura, A.1    Konishi, A.2    Mizuno, K.3
  • 20
    • 11844305919 scopus 로고    scopus 로고
    • Stable transfection of extrinsic Smac gene enhances apoptosis of chemotherapeutic drugs on gastric cancer cells
    • Zheng LD, Tong QS, Wang L, Liu J and Qian W: Stable transfection of extrinsic Smac gene enhances apoptosis of chemotherapeutic drugs on gastric cancer cells. World J Gastroenterol 11: 79-83, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 79-83
    • Zheng, L.D.1    Tong, Q.S.2    Wang, L.3    Liu, J.4    Qian, W.5
  • 21
    • 33751215489 scopus 로고    scopus 로고
    • Relationship between expression of Smac and Survivin and apoptosis of primary hepatocellular carcinoma
    • Bao ST, Gui SQ and Lin MS: Relationship between expression of Smac and Survivin and apoptosis of primary hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int 5: 580-583, 2006.
    • (2006) Hepatobiliary Pancreat Dis Int , vol.5 , pp. 580-583
    • Bao, S.T.1    Gui, S.Q.2    Lin, M.S.3
  • 22
    • 33645021667 scopus 로고    scopus 로고
    • Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates ectablished human hepatoma in vivo
    • Zhao J, Jin J, Zhang X, et al: Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates ectablished human hepatoma in vivo. Cancer Gene Ther 13: 420-427, 2006.
    • (2006) Cancer Gene Ther , vol.13 , pp. 420-427
    • Zhao, J.1    Jin, J.2    Zhang, X.3
  • 23
    • 33646249626 scopus 로고    scopus 로고
    • Altered expression of c-IAP1, survivin and Smac contributes to chemotherapy resistance in thyroid cancer cells
    • Tirro E, Consoli ML, Massimino M, et al: Altered expression of c-IAP1, survivin and Smac contributes to chemotherapy resistance in thyroid cancer cells. Cancer Res 66: 4263-4272, 2006.
    • (2006) Cancer Res , vol.66 , pp. 4263-4272
    • Tirro, E.1    Consoli, M.L.2    Massimino, M.3
  • 24
    • 20044376659 scopus 로고    scopus 로고
    • Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance
    • Mizutani Y, Nakanishi H, Yamamoto K, et al: Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance. J Clin Oncol 23: 448-454, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 448-454
    • Mizutani, Y.1    Nakanishi, H.2    Yamamoto, K.3
  • 25
    • 17844392101 scopus 로고    scopus 로고
    • Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL
    • Rashmi R, Kumar S and Karunagaran D: Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL. Carcinogenesis 26: 713-723, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 713-723
    • Rashmi, R.1    Kumar, S.2    Karunagaran, D.3
  • 26
    • 11144230279 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis - inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
    • Sinicrope FA, Penington RC and Tang XM: Tumor necrosis factor-related apoptosis - inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin Cancer Res 10: 8284-8292, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 8284-8292
    • Sinicrope, F.A.1    Penington, R.C.2    Tang, X.M.3
  • 27
    • 10044265235 scopus 로고    scopus 로고
    • Smac/DIABLO-dependent apoptosis induced by nonsteroidal anti-inflammatory drugs(NSAIDs) in colon cancer cells
    • Kohli M, Yu J, Seaman C, et al: Smac/DIABLO-dependent apoptosis induced by nonsteroidal anti-inflammatory drugs(NSAIDs) in colon cancer cells. Proc Natl Acad Sci USA 101: 16897-16902, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16897-16902
    • Kohli, M.1    Yu, J.2    Seaman, C.3
  • 28
    • 0020853699 scopus 로고
    • General rules for clinical and pathologic studies on cancer of the colon, rectum and anus
    • Japanese Research Society of Cancer of the Colon and Rectum
    • Japanese Research Society of Cancer of the Colon and Rectum: General rules for clinical and pathologic studies on cancer of the colon, rectum and anus. Jpn J Surg 13: 557-573, 1983.
    • (1983) Jpn J Surg , vol.13 , pp. 557-573
  • 29
  • 30
    • 2342615480 scopus 로고    scopus 로고
    • X-Linked Inhibitor of Apoptosis Protein(XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)-mediated apoptosis in human cancer cells
    • Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B and Bunz F: X-Linked Inhibitor of Apoptosis Protein(XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)-mediated apoptosis in human cancer cells. Cancer Res 64: 3006-3008, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3006-3008
    • Cummins, J.M.1    Kohli, M.2    Rago, C.3    Kinzler, K.W.4    Vogelstein, B.5    Bunz, F.6
  • 31
    • 0034667372 scopus 로고    scopus 로고
    • Down regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells
    • Sasaki H, Sheng Y, Kotsuji F, et al: Down regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells. Cancer Res 60: 5659-5666, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5659-5666
    • Sasaki, H.1    Sheng, Y.2    Kotsuji, F.3
  • 32
    • 1942534018 scopus 로고    scopus 로고
    • Regulation of apoptosis proteins in cancer cells by ubiquitin
    • Zhang HG, Wang J, Yang X, Hsu HC and Mountz JD: Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene 23: 2009-2015, 2004.
    • (2004) Oncogene , vol.23 , pp. 2009-2015
    • Zhang, H.G.1    Wang, J.2    Yang, X.3    Hsu, H.C.4    Mountz, J.D.5
  • 33
    • 0035937420 scopus 로고    scopus 로고
    • Cell death inhibition: Keeping caspases in check
    • Goyal L: Cell death inhibition: Keeping caspases in check. Cell 104: 805-808, 2001.
    • (2001) Cell , vol.104 , pp. 805-808
    • Goyal, L.1
  • 34
    • 0035282570 scopus 로고    scopus 로고
    • A conserved XIAPinteraction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
    • Srinivasula SM, Hegde R, Saleh A, et al: A conserved XIAPinteraction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 410: 112-116, 2001.
    • (2001) Nature , vol.410 , pp. 112-116
    • Srinivasula, S.M.1    Hegde, R.2    Saleh, A.3
  • 35
    • 34548036056 scopus 로고    scopus 로고
    • Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: Roles of Fas, Apaf-1, NFkB, IAPs, Smac/ DIABLO, and AIF
    • Huerta S, Heinzerling JH, Anguiano-Hernandez YM, et al: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: Roles of Fas, Apaf-1, NFkB, IAPs, Smac/ DIABLO, and AIF. J Surg Res 142: 184-194, 2007.
    • (2007) J Surg Res , vol.142 , pp. 184-194
    • Huerta, S.1    Heinzerling, J.H.2    Anguiano-Hernandez, Y.M.3
  • 36
    • 32844454337 scopus 로고    scopus 로고
    • Prognostic factors after potentially curative resection in stageII or III colon cancer
    • Ogata Y, Torigoe S, Matono K, et al: Prognostic factors after potentially curative resection in stageII or III colon cancer. Kurume Med J 52: 67-71, 2005.
    • (2005) Kurume Med J , vol.52 , pp. 67-71
    • Ogata, Y.1    Torigoe, S.2    Matono, K.3
  • 38
    • 35648961848 scopus 로고    scopus 로고
    • A dimeric Smac/Diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo
    • Gao Z, Tian Y, Wang J, et al: A dimeric Smac/Diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo. J Biol Chem 282: 30718-30727, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 30718-30727
    • Gao, Z.1    Tian, Y.2    Wang, J.3
  • 39
    • 37549000486 scopus 로고    scopus 로고
    • A Smac mimetic rescue screen reveals roles for inhibitor of apoptsis protein in tumor necrosis factor-a signaling
    • Gaither A, Porter D, Yao Y, et al: A Smac mimetic rescue screen reveals roles for inhibitor of apoptsis protein in tumor necrosis factor-a signaling. Cancer Res 67: 11493-11498, 2007.
    • (2007) Cancer Res , vol.67 , pp. 11493-11498
    • Gaither, A.1    Porter, D.2    Yao, Y.3
  • 40
    • 39149102155 scopus 로고    scopus 로고
    • Smac mimetics sensitize nonsteroidal anti-inflammatory drug induced apoptosis by promoting caspase-3 mediated cytochrome c release
    • Bank A, Wang P, Du C, Yu J and Zhang L: Smac mimetics sensitize nonsteroidal anti-inflammatory drug induced apoptosis by promoting caspase-3 mediated cytochrome c release. Cancer Res 68: 276-284, 2008.
    • (2008) Cancer Res , vol.68 , pp. 276-284
    • Bank, A.1    Wang, P.2    Du, C.3    Yu, J.4    Zhang, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.