-
1
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB: Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51:2944-2950, 2002
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
2
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE: Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54:8-14, 2005
-
(2005)
Diabetes
, vol.54
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
3
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI: Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350:664-671, 2004
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
4
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ: Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 100:8466-8471, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
5
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267-273, 2003
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstråle, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
6
-
-
31044433308
-
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
-
Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI: Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest 115:3587-3593, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 3587-3593
-
-
Morino, K.1
Petersen, K.F.2
Dufour, S.3
Befroy, D.4
Frattini, J.5
Shatzkes, N.6
Neschen, S.7
White, M.F.8
Bilz, S.9
Sono, S.10
Pypaert, M.11
Shulman, G.I.12
-
7
-
-
25644448096
-
Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents
-
Petersen KF, Dufour S, Shulman GI: Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents. PLoS Med 2:e233, 2005
-
(2005)
PLoS Med
, vol.2
-
-
Petersen, K.F.1
Dufour, S.2
Shulman, G.I.3
-
8
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB, Shulman GI: Mitochondrial dysfunction and type 2 diabetes. Science 307:384-387, 2005
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
9
-
-
41949114990
-
Role of mitochondrial dysfunction in insulin resistance
-
Kim JA, Wei Y, Sowers JR: Role of mitochondrial dysfunction in insulin resistance. Circ Res 102:401-414, 2008
-
(2008)
Circ Res
, vol.102
, pp. 401-414
-
-
Kim, J.A.1
Wei, Y.2
Sowers, J.R.3
-
10
-
-
0033031543
-
Recent progress in angiotensin II type 2 receptor research in the cardiovascular system
-
Horiuchi M, Akishita M, Dzau VJ: Recent progress in angiotensin II type 2 receptor research in the cardiovascular system. Hypertension 33:613-621,1999
-
(1999)
Hypertension
, vol.33
, pp. 613-621
-
-
Horiuchi, M.1
Akishita, M.2
Dzau, V.J.3
-
11
-
-
33744904698
-
Effect of antihypertensive agents on the development of type 2 diabetes mellitus
-
Stump CS, Hamilton MT, Sowers JR: Effect of antihypertensive agents on the development of type 2 diabetes mellitus. Mayo Clin Proc 81:796-806,2006
-
(2006)
Mayo Clin Proc
, vol.81
, pp. 796-806
-
-
Stump, C.S.1
Hamilton, M.T.2
Sowers, J.R.3
-
12
-
-
42449125282
-
The renin-angiotensin-aldosterone system: A pivotal role in insulin sensitivity and glycemic control
-
Perkins JM, Davis SN: The renin-angiotensin-aldosterone system: a pivotal role in insulin sensitivity and glycemic control. Curr Opin Endocrinol Diabetes Obes 15:147-152, 2008
-
(2008)
Curr Opin Endocrinol Diabetes Obes
, vol.15
, pp. 147-152
-
-
Perkins, J.M.1
Davis, S.N.2
-
13
-
-
18844449196
-
Why blockade of the renin-angiotensin system reduces the incidence of new- onset diabetes
-
Jandeleit-Dahm KA, Tikellis C, Reid CM, Johnston CI, Cooper ME: Why blockade of the renin-angiotensin system reduces the incidence of new- onset diabetes. J Hypertens 23:463-473, 2005
-
(2005)
J Hypertens
, vol.23
, pp. 463-473
-
-
Jandeleit-Dahm, K.A.1
Tikellis, C.2
Reid, C.M.3
Johnston, C.I.4
Cooper, M.E.5
-
14
-
-
13244267189
-
Of the renin-angiotensin system and reactive oxygen species type 2 diabetes and angiotensin II inhibition
-
Leiter LA, Lewanczuk RZ: Of the renin-angiotensin system and reactive oxygen species type 2 diabetes and angiotensin II inhibition. Am J Hypertens 18:121-128, 2005
-
(2005)
Am J Hypertens
, vol.18
, pp. 121-128
-
-
Leiter, L.A.1
Lewanczuk, R.Z.2
-
15
-
-
38949093861
-
Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase
-
Wei Y, Sowers JR, Clark SE, Li W, Ferrario CM, Stump CS: Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase. Am JPhysiol Endocrinol Metab 294:E345-E351, 2008
-
(2008)
Am JPhysiol Endocrinol Metab
, vol.294
-
-
Wei, Y.1
Sowers, J.R.2
Clark, S.E.3
Li, W.4
Ferrario, C.M.5
Stump, C.S.6
-
16
-
-
33845932608
-
Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells
-
Wei Y, Sowers JR, Nistala R, Gong H, Uptergrove GM, Clark SE, Morris EM, Szary N, Manrique C, Stump CS: Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells. J Biol Chem 28:35137-35146, 2006
-
(2006)
J Biol Chem
, vol.28
, pp. 35137-35146
-
-
Wei, Y.1
Sowers, J.R.2
Nistala, R.3
Gong, H.4
Uptergrove, G.M.5
Clark, S.E.6
Morris, E.M.7
Szary, N.8
Manrique, C.9
Stump, C.S.10
-
17
-
-
0030723979
-
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels: A potential role for serine phosphorylation in insulin/angiotensin II crosstalk
-
Folli F, Kahn CR, Hansen H, Bouchie JL, Feener EP: Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels: a potential role for serine phosphorylation in insulin/angiotensin II crosstalk. J Clin Invest 100:2158-2169, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 2158-2169
-
-
Folli, F.1
Kahn, C.R.2
Hansen, H.3
Bouchie, J.L.4
Feener, E.P.5
-
18
-
-
0036266179
-
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors
-
Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM: Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51:1699-1707, 2002
-
(2002)
Diabetes
, vol.51
, pp. 1699-1707
-
-
Janke, J.1
Engeli, S.2
Gorzelniak, K.3
Luft, F.C.4
Sharma, A.M.5
-
19
-
-
23044505229
-
Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor
-
Kouyama R, Suganami T, Nishida J, Tanaka M, Toyoda T, Kiso M, Chiwata T, Miyamoto Y, Yoshimasa Y, Fukamizu A, Horiuchi M, Hirata Y, Ogawa Y: Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor. Endocrinology 146:3481-3489, 2005
-
(2005)
Endocrinology
, vol.146
, pp. 3481-3489
-
-
Kouyama, R.1
Suganami, T.2
Nishida, J.3
Tanaka, M.4
Toyoda, T.5
Kiso, M.6
Chiwata, T.7
Miyamoto, Y.8
Yoshimasa, Y.9
Fukamizu, A.10
Horiuchi, M.11
Hirata, Y.12
Ogawa, Y.13
-
20
-
-
38749150314
-
cGMP rescues mitochondrial dysfunction induced by glucose and insulin in myocytes
-
cGMP rescues mitochondrial dysfunction induced by glucose and insulin in myocytes. Biochem Biophys Res Commun 367:840-845, 2008
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 840-845
-
-
Mitsuishi, M.1
Miyashita, K.2
Itoh, H.3
-
21
-
-
0025884056
-
Efficient selection for high-expression transfectants with a novel eukaryotic vector
-
Niwa H, Yamamura K, Miyazaki J: Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-199, 1991
-
(1991)
Gene
, vol.108
, pp. 193-199
-
-
Niwa, H.1
Yamamura, K.2
Miyazaki, J.3
-
22
-
-
0037167706
-
Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart
-
Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K: Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart. Circulation 106:1722-1728, 2002
-
(2002)
Circulation
, vol.106
, pp. 1722-1728
-
-
Li, Y.1
Kishimoto, I.2
Saito, Y.3
Harada, M.4
Kuwahara, K.5
Izumi, T.6
Takahashi, N.7
Kawakami, R.8
Tanimoto, K.9
Nakagawa, Y.10
Nakanishi, M.11
Adachi, Y.12
Garbers, D.L.13
Fukamizu, A.14
Nakao, K.15
-
23
-
-
70449158340
-
A simple method for the isolation and purification of total lipids from animal tissues
-
Folch J, Lees M, Sloane Stanley GH: A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509,1957
-
(1957)
J Biol Chem
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
24
-
-
0014576426
-
Metabolic differentiation of distinct muscle types at the level of enzymatic organization
-
Bass A, Brdiczka D, Eyer P, Hofer S, Pette D: Metabolic differentiation of distinct muscle types at the level of enzymatic organization. Eur J Bio-chem 10:198-206, 1969
-
(1969)
Eur J Bio-chem
, vol.10
, pp. 198-206
-
-
Bass, A.1
Brdiczka, D.2
Eyer, P.3
Hofer, S.4
Pette, D.5
-
25
-
-
44849128599
-
Expression and maintenance of mitochondrial DNA: New insights into human disease pathology
-
Shadel GS: Expression and maintenance of mitochondrial DNA: new insights into human disease pathology. Am J Pathol 172:1445-1456, 2008
-
(2008)
Am J Pathol
, vol.172
, pp. 1445-1456
-
-
Shadel, G.S.1
-
26
-
-
33644935649
-
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: An implication for hypertension-related insulin resistance
-
Ran J, Hirano T, Fukui T, Saito K, Kageyama H, Okada K, Adachi M:Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance. Metabolism 55:478-488, 2006
-
(2006)
Metabolism
, vol.55
, pp. 478-488
-
-
Ran, J.1
Hirano, T.2
Fukui, T.3
Saito, K.4
Kageyama, H.5
Okada, K.6
Adachi, M.7
-
27
-
-
33745419401
-
Role of adiponectin in human skeletal muscle bioenergetics
-
Civitarese AE, Ukropcova B, Carling S, Hulver M, DeFronzo RA, Man- darino L, Ravussin E, Smith SR: Role of adiponectin in human skeletal muscle bioenergetics. Cell Metab 4:75-87, 2006
-
(2006)
Cell Metab
, vol.4
, pp. 75-87
-
-
Civitarese, A.E.1
Ukropcova, B.2
Carling, S.3
Hulver, M.4
DeFronzo, R.A.5
Man- darino, L.6
Ravussin, E.7
Smith, S.R.8
-
29
-
-
33744826243
-
Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine
-
de Cavanagh EM, Toblli JE, Ferder L, Piotrkowski B, Stella I, Inserra F: Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine. Am J Physiol Regul Integr Comp Physiol 290:R1616-R1625, 2006
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.290
-
-
de Cavanagh, E.M.1
Toblli, J.E.2
Ferder, L.3
Piotrkowski, B.4
Stella, I.5
Inserra, F.6
-
30
-
-
0038718692
-
Enalapril and losartan attenuate mitochondrial dysfunction in aged rats
-
de Cavanagh EM, Piotrkowski B, Basso N, Stella I, Inserra F, Ferder L, Fraga CG: Enalapril and losartan attenuate mitochondrial dysfunction in aged rats. FASEB J 17:1096-1098, 2003
-
(2003)
FASEB J
, vol.17
, pp. 1096-1098
-
-
de Cavanagh, E.M.1
Piotrkowski, B.2
Basso, N.3
Stella, I.4
Inserra, F.5
Ferder, L.6
Fraga, C.G.7
-
31
-
-
2342525336
-
Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice
-
Shiuchi T, Iwai M, Li HS, Wu L, Min LJ, Li JM, Okumura M, Cui TX, Horiuchi M: Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice. Hypertension 43:1003-1010, 2004
-
(2004)
Hypertension
, vol.43
, pp. 1003-1010
-
-
Shiuchi, T.1
Iwai, M.2
Li, H.S.3
Wu, L.4
Min, L.J.5
Li, J.M.6
Okumura, M.7
Cui, T.X.8
Horiuchi, M.9
-
32
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan DA, Lillioja S, Kriketos AD, Milner MR, Baur LA, Bogardus C, Jenkins AB, Storlien LH: Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46:983-988, 1997
-
(1997)
Diabetes
, vol.46
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
Milner, M.R.4
Baur, L.A.5
Bogardus, C.6
Jenkins, A.B.7
Storlien, L.H.8
-
33
-
-
0032764784
-
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
-
Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L: Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48:1600-1606, 1999
-
(1999)
Diabetes
, vol.48
, pp. 1600-1606
-
-
Perseghin, G.1
Scifo, P.2
De Cobelli, F.3
Pagliato, E.4
Battezzati, A.5
Arcelloni, C.6
Vanzulli, A.7
Testolin, G.8
Pozza, G.9
Del Maschio, A.10
Luzi, L.11
-
34
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
Griffin ME, Marcucci MJ, Cline GW, Bell K, Barucci N, Lee D, Goodyear LJ, Kraegen EW, White MF, Shulman GI: Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48:1270-1274, 1999
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
Bell, K.4
Barucci, N.5
Lee, D.6
Goodyear, L.J.7
Kraegen, E.W.8
White, M.F.9
Shulman, G.I.10
-
35
-
-
43249083481
-
Free fatty acids and skeletal muscle insulin resistance
-
Kraegen EW, Cooney GJ: Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 19:235-241, 2008
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 235-241
-
-
Kraegen, E.W.1
Cooney, G.J.2
-
36
-
-
0033400310
-
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
-
Kelley DE, Goodpaster B, Wing RR, Simoneau JA: Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 277:E1130-E1141, 1999
-
(1999)
Am J Physiol
, vol.277
-
-
Kelley, D.E.1
Goodpaster, B.2
Wing, R.R.3
Simoneau, J.A.4
-
37
-
-
34248141686
-
-
Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI: Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes 56:13761381, 2007
-
Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI: Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes 56:13761381, 2007
-
-
-
-
38
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
-
Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P: Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J 26:1913-1923, 2007
-
(2007)
EMBO J
, vol.26
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
Lerin, C.4
Kim, S.H.5
Mostoslavsky, R.6
Alt, F.W.7
Wu, Z.8
Puigserver, P.9
-
39
-
-
37349073763
-
Diet, energy metabolism and mitochondrial biogenesis
-
Civitarese AE, Smith SR, Ravussin E: Diet, energy metabolism and mitochondrial biogenesis. Curr Opin Clin Nutr Metab Care 10:679-687,2007
-
(2007)
Curr Opin Clin Nutr Metab Care
, vol.10
, pp. 679-687
-
-
Civitarese, A.E.1
Smith, S.R.2
Ravussin, E.3
-
40
-
-
37349023268
-
Muscular mitochondrial dysfunction and type 2 diabetes mellitus
-
Schrauwen-Hinderling VB, Roden M, Kooi ME, Hesselink MK, Schrauwen P: Muscular mitochondrial dysfunction and type 2 diabetes mellitus. Curr Opin Clin Nutr Metab Care 10:698-703, 2007
-
(2007)
Curr Opin Clin Nutr Metab Care
, vol.10
, pp. 698-703
-
-
Schrauwen-Hinderling, V.B.1
Roden, M.2
Kooi, M.E.3
Hesselink, M.K.4
Schrauwen, P.5
|