메뉴 건너뛰기




Volumn 106, Issue 4, 2009, Pages 714-728

Loss of cell-cell contacts induces NF-κB via RhoA-mediated activation of protein kinase D1

Author keywords

NF B; PKD; Rho; Src

Indexed keywords

ACTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C; PROTEIN KINASE D; PROTEIN KINASE D 1; PROTEIN SERINE KINASE; PROTEIN TYROSINE KINASE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THREONINE; UNCLASSIFIED DRUG;

EID: 62649104179     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22067     Document Type: Article
Times cited : (60)

References (69)
  • 1
    • 33845477045 scopus 로고    scopus 로고
    • p120-ctn: A nexus for contextual signaling via Rho GTPases
    • Anastasiadis PZ. 2007. p120-ctn: A nexus for contextual signaling via Rho GTPases. Biochim Biophys Acta 1773:34-46.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 34-46
    • Anastasiadis, P.Z.1
  • 3
    • 9144268981 scopus 로고    scopus 로고
    • RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65
    • Anwar KN, Fazal F, Malik AB, Rahman A. 2004. RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65. J Immunol 173:6965-6972.
    • (2004) J Immunol , vol.173 , pp. 6965-6972
    • Anwar, K.N.1    Fazal, F.2    Malik, A.B.3    Rahman, A.4
  • 4
    • 0035158377 scopus 로고    scopus 로고
    • RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
    • Arthur WT, Burridge K. 2001. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 12:2711-2720.
    • (2001) Mol Biol Cell , vol.12 , pp. 2711-2720
    • Arthur, W.T.1    Burridge, K.2
  • 5
    • 24344432006 scopus 로고    scopus 로고
    • Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling
    • Auer A, von Blume J, Sturany S, von Wichert G, Van Lint J, Vandenheede J, Adler G, Seufferlein T. 2005. Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling. Mol Biol Cell 16:4375-4385.
    • (2005) Mol Biol Cell , vol.16 , pp. 4375-4385
    • Auer, A.1    von Blume, J.2    Sturany, S.3    von Wichert, G.4    Van Lint, J.5    Vandenheede, J.6    Adler, G.7    Seufferlein, T.8
  • 6
    • 0038446034 scopus 로고    scopus 로고
    • ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: Effects on tumor growth and therapeutic consequences
    • Benitah SA, Valeron PF, Lacal JC. 2003. ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: Effects on tumor growth and therapeutic consequences. Mol Biol Cell 14:3041-3054.
    • (2003) Mol Biol Cell , vol.14 , pp. 3041-3054
    • Benitah, S.A.1    Valeron, P.F.2    Lacal, J.C.3
  • 7
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga VM, Machesky LM, Hall A, Hotchin NA. 1997. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 137:1421-1431.
    • (1997) J Cell Biol , vol.137 , pp. 1421-1431
    • Braga, V.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 8
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • Burridge K, Wennerberg K. 2004. Rho and Rac take center stage. Cell 116: 167-179.
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 9
    • 3142582003 scopus 로고    scopus 로고
    • Lipid raft disruption triggers protein kinase C and Src-dependent protein kinase D activation and Kidins220 phosphorylation in neuronal cells
    • Cabrera-Poch N, Sanchez-Ruiloba L, Rodriguez-Martinez M, Iglesias T. 2004. Lipid raft disruption triggers protein kinase C and Src-dependent protein kinase D activation and Kidins220 phosphorylation in neuronal cells. J Biol Chem 279:28592-28602.
    • (2004) J Biol Chem , vol.279 , pp. 28592-28602
    • Cabrera-Poch, N.1    Sanchez-Ruiloba, L.2    Rodriguez-Martinez, M.3    Iglesias, T.4
  • 10
  • 12
    • 11244310645 scopus 로고    scopus 로고
    • Protein kinase C-independent effects of protein kinase D3 in glucose transport in L6 myotubes
    • Chen J, Lu G, Wang QJ. 2005. Protein kinase C-independent effects of protein kinase D3 in glucose transport in L6 myotubes. Mol Pharmacol 67:152-162.
    • (2005) Mol Pharmacol , vol.67 , pp. 152-162
    • Chen, J.1    Lu, G.2    Wang, Q.J.3
  • 13
    • 36148962891 scopus 로고    scopus 로고
    • A novel tyrosine phosphorylation site in protein kinase D contributes to oxidative stress-mediated activation
    • Doppler H, Storz P. 2007. A novel tyrosine phosphorylation site in protein kinase D contributes to oxidative stress-mediated activation. J Biol Chem 282:31873-31881.
    • (2007) J Biol Chem , vol.282 , pp. 31873-31881
    • Doppler, H.1    Storz, P.2
  • 14
    • 34548133221 scopus 로고    scopus 로고
    • PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration
    • Eiseler T, Schmid MA, Topbas F, Pfizenmaier K, Hausser A. 2007. PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration. FEBS Lett 581:4279-4287.
    • (2007) FEBS Lett , vol.581 , pp. 4279-4287
    • Eiseler, T.1    Schmid, M.A.2    Topbas, F.3    Pfizenmaier, K.4    Hausser, A.5
  • 15
    • 0032775007 scopus 로고    scopus 로고
    • Regulation of phospholipase D
    • Exton JH. 1999. Regulation of phospholipase D. Biochim Biophys Acta 1439:121-133.
    • (1999) Biochim Biophys Acta , vol.1439 , pp. 121-133
    • Exton, J.H.1
  • 16
    • 0035651254 scopus 로고    scopus 로고
    • Rho-family GTPases in cadherin-mediated cell-cell adhesion
    • Fukata M, Kaibuchi K. 2001. Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nat Rev Mol Cell Biol 2:887-897.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 887-897
    • Fukata, M.1    Kaibuchi, K.2
  • 17
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 18
    • 26944446652 scopus 로고    scopus 로고
    • Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex
    • Hausser A, Storz P, Martens S, Link G, Toker A, Pfizenmaier K. 2005. Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex. Nat Cell Biol 7:880-886.
    • (2005) Nat Cell Biol , vol.7 , pp. 880-886
    • Hausser, A.1    Storz, P.2    Martens, S.3    Link, G.4    Toker, A.5    Pfizenmaier, K.6
  • 20
    • 0030974514 scopus 로고    scopus 로고
    • Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer
    • Hiscox S, Jiang WG. 1997. Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer. Anticancer Res 17:1349-1354.
    • (1997) Anticancer Res , vol.17 , pp. 1349-1354
    • Hiscox, S.1    Jiang, W.G.2
  • 21
    • 12544257169 scopus 로고    scopus 로고
    • E-cadherin phosphorylation by protein kinase D1/protein kinase Cμ is associated with altered cellular aggregation and motility in prostate cancer
    • Jaggi M, Rao PS, Smith DJ, Wheelock MJ, Johnson KR, Hemstreet GP, Balaji KC. 2005. E-cadherin phosphorylation by protein kinase D1/protein kinase Cμ is associated with altered cellular aggregation and motility in prostate cancer. Cancer Res 65:483-492.
    • (2005) Cancer Res , vol.65 , pp. 483-492
    • Jaggi, M.1    Rao, P.S.2    Smith, D.J.3    Wheelock, M.J.4    Johnson, K.R.5    Hemstreet, G.P.6    Balaji, K.C.7
  • 22
    • 4043052971 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Twist in development and metastasis
    • Kang Y, Massague J. 2004. Epithelial-mesenchymal transitions: Twist in development and metastasis. Cell 118:277-279.
    • (2004) Cell , vol.118 , pp. 277-279
    • Kang, Y.1    Massague, J.2
  • 23
    • 44349149912 scopus 로고    scopus 로고
    • Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase-c-Src complex
    • Kim YB, Choi S, Choi MC, Oh MA, Lee SA, Cho M, Mizuno K, Kim SH, Lee JW. 2008. Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase-c-Src complex. J Biol Chem 283:10089-10096.
    • (2008) J Biol Chem , vol.283 , pp. 10089-10096
    • Kim, Y.B.1    Choi, S.2    Choi, M.C.3    Oh, M.A.4    Lee, S.A.5    Cho, M.6    Mizuno, K.7    Kim, S.H.8    Lee, J.W.9
  • 24
    • 3142543759 scopus 로고    scopus 로고
    • Li J, O'Connor KL, Hellmich MR, Greeley GH, Jr., Townsend CM, Jr., Evers BM. 2004. The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase. J Biol Chem 279:28466-28474.
    • Li J, O'Connor KL, Hellmich MR, Greeley GH, Jr., Townsend CM, Jr., Evers BM. 2004. The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase. J Biol Chem 279:28466-28474.
  • 28
    • 0026742310 scopus 로고
    • Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
    • Matsuyoshi N, Hamaguchi M, Taniguchi S, Nagafuchi A, Tsukita S, Takeichi M. 1992. Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol 118:703-714.
    • (1992) J Cell Biol , vol.118 , pp. 703-714
    • Matsuyoshi, N.1    Hamaguchi, M.2    Taniguchi, S.3    Nagafuchi, A.4    Tsukita, S.5    Takeichi, M.6
  • 30
    • 10844235691 scopus 로고    scopus 로고
    • Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells
    • Mihailovic T, Marx M, Auer A, Van Lint J, Schmid M, Weber C, Seufferlein T. 2004. Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells. Cancer Res 64:8939-8944.
    • (2004) Cancer Res , vol.64 , pp. 8939-8944
    • Mihailovic, T.1    Marx, M.2    Auer, A.3    Van Lint, J.4    Schmid, M.5    Weber, C.6    Seufferlein, T.7
  • 31
    • 0032557526 scopus 로고    scopus 로고
    • Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases
    • Montaner S, Perona R, Saniger L, Lacal JC. 1998. Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases. J Biol Chem 273:12779-12785.
    • (1998) J Biol Chem , vol.273 , pp. 12779-12785
    • Montaner, S.1    Perona, R.2    Saniger, L.3    Lacal, J.C.4
  • 32
    • 33748747222 scopus 로고    scopus 로고
    • Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D
    • Mullin MJ, Lightfoot K, Marklund U, Cantrell DA. 2006. Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D. J Biol Chem 281:25089-25096.
    • (2006) J Biol Chem , vol.281 , pp. 25089-25096
    • Mullin, M.J.1    Lightfoot, K.2    Marklund, U.3    Cantrell, D.A.4
  • 33
    • 2642515740 scopus 로고    scopus 로고
    • Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells
    • Nemeth ZH, Deitch EA, Davidson MT, Szabo C, Vizi ES, Hasko G. 2004. Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells. J Cell Physiol 200:71-81.
    • (2004) J Cell Physiol , vol.200 , pp. 71-81
    • Nemeth, Z.H.1    Deitch, E.A.2    Davidson, M.T.3    Szabo, C.4    Vizi, E.S.5    Hasko, G.6
  • 34
    • 0034618050 scopus 로고    scopus 로고
    • p120 catenin regulates the actin cytoskeleton via Rho family GTPases
    • Noren NK, Liu BP, Burridge K, Kreft B. 2000. p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol 150:567-580.
    • (2000) J Cell Biol , vol.150 , pp. 567-580
    • Noren, N.K.1    Liu, B.P.2    Burridge, K.3    Kreft, B.4
  • 37
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB, Schwartz MA. 1999. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18:578-585.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 39
    • 0036305635 scopus 로고    scopus 로고
    • ROCK and Dia have opposing effects on adherens junctions downstream of Rho
    • Sahai E, Marshall CJ. 2002b. ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat Cell Biol 4:408-415.
    • (2002) Nat Cell Biol , vol.4 , pp. 408-415
    • Sahai, E.1    Marshall, C.J.2
  • 40
    • 33745815978 scopus 로고    scopus 로고
    • Protein kinase D intracellular localization and activity control kinase D-interacting substrate of 220-kDa traffic through a postsynaptic density-95/discs large/zonula occludens-1-binding motif
    • Sanchez-Ruiloba L, Cabrera-Poch N, Rodriguez-Martinez M, Lopez-Menendez C, Jean-Mairet RM, Higuero AM, Iglesias T. 2006. Protein kinase D intracellular localization and activity control kinase D-interacting substrate of 220-kDa traffic through a postsynaptic density-95/discs large/zonula occludens-1-binding motif. J Biol Chem 281:18888-18900.
    • (2006) J Biol Chem , vol.281 , pp. 18888-18900
    • Sanchez-Ruiloba, L.1    Cabrera-Poch, N.2    Rodriguez-Martinez, M.3    Lopez-Menendez, C.4    Jean-Mairet, R.M.5    Higuero, A.M.6    Iglesias, T.7
  • 41
    • 9244237677 scopus 로고    scopus 로고
    • Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma
    • Simpson KJ, Dugan AS, Mercurio AM. 2004. Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma. Cancer Res 64:8694-8701.
    • (2004) Cancer Res , vol.64 , pp. 8694-8701
    • Simpson, K.J.1    Dugan, A.S.2    Mercurio, A.M.3
  • 44
    • 33744812402 scopus 로고    scopus 로고
    • Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/ PKC-δ pathway activation
    • Song J, Li J, Lulla A, Evers BM, Chung DH. 2006. Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/ PKC-δ pathway activation. Am J Physiol Cell Physiol 290:C1469-C1476.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Song, J.1    Li, J.2    Lulla, A.3    Evers, B.M.4    Chung, D.H.5
  • 45
    • 33845953689 scopus 로고    scopus 로고
    • Mitochondrial ROS - Radical detoxification, mediated by protein kinase D
    • Storz P. 2007. Mitochondrial ROS - Radical detoxification, mediated by protein kinase D. Trends Cell Biol 17:13-18.
    • (2007) Trends Cell Biol , vol.17 , pp. 13-18
    • Storz, P.1
  • 46
    • 0037413711 scopus 로고    scopus 로고
    • Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway
    • Storz P, Toker A. 2003. Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway. EMBO J 22:109-120.
    • (2003) EMBO J , vol.22 , pp. 109-120
    • Storz, P.1    Toker, A.2
  • 47
    • 0038043212 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation
    • Storz P, Doppler H, Johannes FJ, Toker A. 2003. Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation. J Biol Chem 278:17969-17976.
    • (2003) J Biol Chem , vol.278 , pp. 17969-17976
    • Storz, P.1    Doppler, H.2    Johannes, F.J.3    Toker, A.4
  • 48
    • 4844224721 scopus 로고    scopus 로고
    • Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB
    • Storz P, Doppler H, Toker A. 2004a. Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB. Mol Pharmacol 66:870-879.
    • (2004) Mol Pharmacol , vol.66 , pp. 870-879
    • Storz, P.1    Doppler, H.2    Toker, A.3
  • 49
    • 1642379541 scopus 로고    scopus 로고
    • Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling
    • Storz P, Doppler H, Toker A. 2004b. Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling. Mol Cell Biol 24:2614-2626.
    • (2004) Mol Cell Biol , vol.24 , pp. 2614-2626
    • Storz, P.1    Doppler, H.2    Toker, A.3
  • 50
    • 17144404884 scopus 로고    scopus 로고
    • Functional dichotomy of A20 in apoptotic and necrotic cell death
    • Storz P, Doppler H, Ferran C, Grey ST, Toker A. 2005a. Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J 387:47-55.
    • (2005) Biochem J , vol.387 , pp. 47-55
    • Storz, P.1    Doppler, H.2    Ferran, C.3    Grey, S.T.4    Toker, A.5
  • 51
    • 25444449225 scopus 로고    scopus 로고
    • Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species
    • Storz P, Doppler H, Toker A. 2005b. Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species. Mol Cell Biol 25:8520-8530.
    • (2005) Mol Cell Biol , vol.25 , pp. 8520-8530
    • Storz, P.1    Doppler, H.2    Toker, A.3
  • 52
    • 0030718609 scopus 로고    scopus 로고
    • Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
    • Takaishi K, Sasaki T, Kotani H, Nishioka H, Takai Y. 1997. Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J Cell Biol 139:1047-1059.
    • (1997) J Cell Biol , vol.139 , pp. 1047-1059
    • Takaishi, K.1    Sasaki, T.2    Kotani, H.3    Nishioka, H.4    Takai, Y.5
  • 53
    • 0025913788 scopus 로고
    • Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated
    • Tsukita S, Oishi K, Akiyama T, Yamanashi Y, Yamamoto T, Tsukita S. 1991. Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated. J Cell Biol 113:867-879.
    • (1991) J Cell Biol , vol.113 , pp. 867-879
    • Tsukita, S.1    Oishi, K.2    Akiyama, T.3    Yamanashi, Y.4    Yamamoto, T.5    Tsukita, S.6
  • 56
    • 0026539999 scopus 로고
    • Protein kinase C activation by phorbol esters induces chromaffin cell cortical filamentous actin disassembly and increases the initial rate of exocytosis in response to nicotinic receptor stimulation
    • Vitale ML, Rodriguez Del Castillo A, Trifaro JM. 1992. Protein kinase C activation by phorbol esters induces chromaffin cell cortical filamentous actin disassembly and increases the initial rate of exocytosis in response to nicotinic receptor stimulation. Neuroscience 51:463-474.
    • (1992) Neuroscience , vol.51 , pp. 463-474
    • Vitale, M.L.1    Rodriguez Del Castillo, A.2    Trifaro, J.M.3
  • 57
    • 0034595789 scopus 로고    scopus 로고
    • Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C
    • Waldron RT, Rozengurt E. 2000. Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C. J Biol Chem 275:17114-17121.
    • (2000) J Biol Chem , vol.275 , pp. 17114-17121
    • Waldron, R.T.1    Rozengurt, E.2
  • 58
    • 0037414763 scopus 로고    scopus 로고
    • Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain
    • Waldron RT, Rozengurt E. 2003. Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. J Biol Chem 278:154-163.
    • (2003) J Biol Chem , vol.278 , pp. 154-163
    • Waldron, R.T.1    Rozengurt, E.2
  • 59
    • 0033015540 scopus 로고    scopus 로고
    • Phosphorylation-dependent protein kinase D activation
    • Waldron RT, Iglesias T, Rozengurt E. 1999. Phosphorylation-dependent protein kinase D activation. Electrophoresis 20:382-390.
    • (1999) Electrophoresis , vol.20 , pp. 382-390
    • Waldron, R.T.1    Iglesias, T.2    Rozengurt, E.3
  • 60
    • 3042637596 scopus 로고    scopus 로고
    • Oxidative stress induces protein kinase C-mediated activation loop phosphorylation and nuclear redistribution of protein kinase D
    • Waldron RT, Rey O, Zhukova E, Rozengurt E. 2004. Oxidative stress induces protein kinase C-mediated activation loop phosphorylation and nuclear redistribution of protein kinase D. J Biol Chem 279:27482-27493.
    • (2004) J Biol Chem , vol.279 , pp. 27482-27493
    • Waldron, R.T.1    Rey, O.2    Zhukova, E.3    Rozengurt, E.4
  • 61
    • 0034823910 scopus 로고    scopus 로고
    • Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia
    • Walsh SV, Hopkins AM, Chen J, Narumiya S, Parkos CA, Nusrat A. 2001. Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia. Gastroenterology 121:566-579.
    • (2001) Gastroenterology , vol.121 , pp. 566-579
    • Walsh, S.V.1    Hopkins, A.M.2    Chen, J.3    Narumiya, S.4    Parkos, C.A.5    Nusrat, A.6
  • 62
    • 33744926666 scopus 로고    scopus 로고
    • PKD at the crossroads of DAG and PKC signaling
    • Wang QJ. 2006. PKD at the crossroads of DAG and PKC signaling. Trends Pharmacol Sci 27:317-323.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 317-323
    • Wang, Q.J.1
  • 63
    • 0242666266 scopus 로고    scopus 로고
    • A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells
    • Wang L, Yang L, Luo Y, Zheng Y. 2003. A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells. J Biol Chem 278:44617-44625.
    • (2003) J Biol Chem , vol.278 , pp. 44617-44625
    • Wang, L.1    Yang, L.2    Luo, Y.3    Zheng, Y.4
  • 64
    • 34249281332 scopus 로고    scopus 로고
    • The cofilin pathway in breast cancer invasion and metastasis
    • Wang W, Eddy R, Condeelis J. 2007. The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer 7:429-440.
    • (2007) Nat Rev Cancer , vol.7 , pp. 429-440
    • Wang, W.1    Eddy, R.2    Condeelis, J.3
  • 66
    • 0141651204 scopus 로고    scopus 로고
    • Cadherins as modulators of cellular phenotype
    • Wheelock MJ, Johnson KR. 2003b. Cadherins as modulators of cellular phenotype. Annu Rev Cell Dev Biol 19:207-235.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 207-235
    • Wheelock, M.J.1    Johnson, K.R.2
  • 69
    • 0035914392 scopus 로고    scopus 로고
    • Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13
    • Yuan J, Slice LW, Rozengurt E. 2001. Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. J Biol Chem 276:38619-38627.
    • (2001) J Biol Chem , vol.276 , pp. 38619-38627
    • Yuan, J.1    Slice, L.W.2    Rozengurt, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.