-
1
-
-
27744494137
-
Antibiotic resistance in Staphylococcus aureus and its relevance in therapy
-
Bal,A.M. and Gould,I.M. (2005) Antibiotic resistance in Staphylococcus aureus and its relevance in therapy. Expert Opin. Pharmacother., 6, 2257-2269.
-
(2005)
Expert Opin. Pharmacother
, vol.6
, pp. 2257-2269
-
-
Bal, A.M.1
Gould, I.M.2
-
2
-
-
0032695922
-
Bacterial antibiotic efflux systems of medical importance
-
Kohler,T., Pechere,J.C. and Plesiat,P. (1999) Bacterial antibiotic efflux systems of medical importance. Cell. Mol. Life Sci. (CMLS), V56, 771-778.
-
(1999)
Cell. Mol. Life Sci. (CMLS)
, vol.56
, pp. 771-778
-
-
Kohler, T.1
Pechere, J.C.2
Plesiat, P.3
-
3
-
-
23444456920
-
Prevention of drug access to bacterial targets: Permeability barriers and active efflux
-
Nikaido,H. (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science, 264, 382-388.
-
(1994)
Science
, vol.264
, pp. 382-388
-
-
Nikaido, H.1
-
4
-
-
0028420272
-
-
Resistance to antibiotics mediated by target alterations
-
Spratt,B.G. (1994) Resistance to antibiotics mediated by target alterations. Science, 64, 388-393.
-
(1994)
Science
, vol.64
, pp. 388-393
-
-
Spratt, B.G.1
-
5
-
-
33745247409
-
Antimicrobial resistance in gram-positive bacteria
-
Rice,L.B. (2006) Antimicrobial resistance in gram-positive bacteria. Am. J. Infect. Control, 34, S11-S19.
-
(2006)
Am. J. Infect. Control
, vol.34
-
-
Rice, L.B.1
-
6
-
-
33644552115
-
Efflux systems in bacterial pathogens: An opportunity for therapeutic intervention? An industry view
-
Lynch,A.S. (2006) Efflux systems in bacterial pathogens: An opportunity for therapeutic intervention? An industry view. Biochem. Pharmacol. 71, 949-956.
-
(2006)
Biochem. Pharmacol
, vol.71
, pp. 949-956
-
-
Lynch, A.S.1
-
7
-
-
0036527636
-
Multidrug resistance: Can different keys open the same lock?
-
Kaur,P. (2002) Multidrug resistance: Can different keys open the same lock? Drug Resist. Updat., 5, 61-64.
-
(2002)
Drug Resist. Updat
, vol.5
, pp. 61-64
-
-
Kaur, P.1
-
8
-
-
55549105779
-
Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes
-
Huet,A., Raygada,J., Mendiratta,K., Seo,S. and Kaatz,G. (2008) Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes. Microbiology, 154, 3144-3153.
-
(2008)
Microbiology
, vol.154
, pp. 3144-3153
-
-
Huet, A.1
Raygada, J.2
Mendiratta, K.3
Seo, S.4
Kaatz, G.5
-
9
-
-
18244388696
-
Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein
-
Kaatz,G.W., McAleese,F. and Seo,S.M. (2005) Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. Antimicrob. Agents Chemother., 49, 1857-1864.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 1857-1864
-
-
Kaatz, G.W.1
McAleese, F.2
Seo, S.M.3
-
10
-
-
18244403495
-
A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to Tigecycline
-
McAleese,F., Petersen,P., Ruzin,A., Dunman,P.M., Murphy,E., Projan,S.J. and Bradford,P.A. (2005) A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to Tigecycline. Antimicrob. Agents Chemother., 49, 1865-1871.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 1865-1871
-
-
McAleese, F.1
Petersen, P.2
Ruzin, A.3
Dunman, P.M.4
Murphy, E.5
Projan, S.J.6
Bradford, P.A.7
-
11
-
-
33645756567
-
MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein
-
Kaatz,G.W., DeMarco,C.E. and Seo,S.M. (2006) MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein. Antimicrob. Agents Chemother., 50, 1276-1281.
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 1276-1281
-
-
Kaatz, G.W.1
DeMarco, C.E.2
Seo, S.M.3
-
12
-
-
35948985469
-
Efflux-related resistance to Norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus
-
DeMarco,C.E., Cushing,L.A., Frempong-Manso,E., Seo,S.M., Jaravaza,T.A.A. and Kaatz,G.W. (2007) Efflux-related resistance to Norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus. Antimicrob. Agents Chemother., 51, 3235-3239.
-
(2007)
Antimicrob. Agents Chemother
, vol.51
, pp. 3235-3239
-
-
DeMarco, C.E.1
Cushing, L.A.2
Frempong-Manso, E.3
Seo, S.M.4
Jaravaza, T.A.A.5
Kaatz, G.W.6
-
13
-
-
33645858540
-
Regulation of virulence by members of the MarR/SlyA family
-
Ellison,D.W. and Miller,V.L. (2006) Regulation of virulence by members of the MarR/SlyA family. Curr. Opin. Microbiol., 9, 153-159.
-
(2006)
Curr. Opin. Microbiol
, vol.9
, pp. 153-159
-
-
Ellison, D.W.1
Miller, V.L.2
-
14
-
-
31344443334
-
Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins
-
Wilkinson,S.P. and Grove,A. (2006) Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins. Curr. Issues Mol. Biol., 8, 51-62.
-
(2006)
Curr. Issues Mol. Biol
, vol.8
, pp. 51-62
-
-
Wilkinson, S.P.1
Grove, A.2
-
15
-
-
0034887133
-
The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Å resolution
-
Alekshun,M.N., Levy,S.B., Mealy,T.R., Seaton,B.A. and Head,J.F. (2001) The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Å resolution. Nat. Struct. Mol. Biol., 8 710-714.
-
(2001)
Nat. Struct. Mol. Biol
, vol.8
, pp. 710-714
-
-
Alekshun, M.N.1
Levy, S.B.2
Mealy, T.R.3
Seaton, B.A.4
Head, J.F.5
-
16
-
-
40649118187
-
Structural insight on the mechanism of regulation of the MarR family of proteins: High-resolution crystal structure of a transcriptional repressor from methanobacterium thermoautotrophicum
-
Saridakis,V., Shahinas,D., Xu,X. and Christendat,D. (2008) Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from methanobacterium thermoautotrophicum. J. Mol. Biol., 377, 655-667.
-
(2008)
J. Mol. Biol
, vol.377
, pp. 655-667
-
-
Saridakis, V.1
Shahinas, D.2
Xu, X.3
Christendat, D.4
-
17
-
-
0345531110
-
Molecular determinants of the hpa regulatory system of Escherichia coli: The HpaR repressor
-
Galan,B., Kolb,A., Sanz,J.M., Garcia,J.L. and Prieto,M.A. (2003) Molecular determinants of the hpa regulatory system of Escherichia coli: The HpaR repressor. Nucleic Acids Res., 31, 6598-6609.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6598-6609
-
-
Galan, B.1
Kolb, A.2
Sanz, J.M.3
Garcia, J.L.4
Prieto, M.A.5
-
18
-
-
0032839007
-
Purification and ligand binding of EmrR, a regulator of a multidrug transporter
-
Brooun,A., Tomashek,J.J. and Lewis,K. (1999) Purification and ligand binding of EmrR, a regulator of a multidrug transporter. J. Bacteriol., 181, 5131-5133.
-
(1999)
J. Bacteriol
, vol.181
, pp. 5131-5133
-
-
Brooun, A.1
Tomashek, J.J.2
Lewis, K.3
-
19
-
-
20544435632
-
Negative cooperativity of uric acid binding to the transcriptional regulator HucR from Deinococcus radiodurans
-
Wilkinson,S.P. and Grove,A. (2005) Negative cooperativity of uric acid binding to the transcriptional regulator HucR from Deinococcus radiodurans. J. Mol. Biol., 350, 617-630.
-
(2005)
J. Mol. Biol
, vol.350
, pp. 617-630
-
-
Wilkinson, S.P.1
Grove, A.2
-
20
-
-
0033798010
-
The EmrR protein represses the Escherichia coli emrRAB multidrug resistance Operon by directly binding to its promoter region
-
Xiong,A., Gottman,A., Park,C., Baetens,M., Pandza,S. and Matin,A. (2000) The EmrR protein represses the Escherichia coli emrRAB multidrug resistance Operon by directly binding to its promoter region. Antimicrob. Agents Chemother., 44, 2905-2907.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 2905-2907
-
-
Xiong, A.1
Gottman, A.2
Park, C.3
Baetens, M.4
Pandza, S.5
Matin, A.6
-
21
-
-
0035824388
-
Structural mechanisms of QacR induction and multidrug recognition
-
Schumacher,M.A., Miller,M.C., Grkovic,S., Brown,M.H., Skurray,R.A. and Brennan,R.G. (2001) Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2158-2163.
-
(2001)
Science
, vol.294
, pp. 2158-2163
-
-
Schumacher, M.A.1
Miller, M.C.2
Grkovic, S.3
Brown, M.H.4
Skurray, R.A.5
Brennan, R.G.6
-
22
-
-
0035905808
-
Crystal structure of the transcription activator BmrR bound to DNA and a drug
-
Heldwein,E.E.Z. and Brennan,R.G. (2001) Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature, 409, 378-382.
-
(2001)
Nature
, vol.409
, pp. 378-382
-
-
Heldwein, E.E.Z.1
Brennan, R.G.2
-
23
-
-
34248152648
-
Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials
-
Alguel,Y., Meng,C., Tern,W., Krell,T., Ramos,J.L., Gallegos,M.-T. and Zhang,X. (2007) Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials. J. Mol. Biol., 369, 829-840.
-
(2007)
J. Mol. Biol
, vol.369
, pp. 829-840
-
-
Alguel, Y.1
Meng, C.2
Tern, W.3
Krell, T.4
Ramos, J.L.5
Gallegos, M.-T.6
Zhang, X.7
-
24
-
-
0036040835
-
Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors
-
Schumacher,M.A. and Brennan,R.G. (2002) Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors. Mol. Microbiol., 45, 885-893.
-
(2002)
Mol. Microbiol
, vol.45
, pp. 885-893
-
-
Schumacher, M.A.1
Brennan, R.G.2
-
25
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford,M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
26
-
-
0031045585
-
Preparation of seleomethionyl proteins for phase determination
-
Academic Press
-
Doublié,S. (1997) Preparation of seleomethionyl proteins for phase determination. Methods in Enzymol. Academic Press, Vol. 276, pp. 523-530.
-
(1997)
Methods in Enzymol
, vol.276
, pp. 523-530
-
-
Doublié, S.1
-
27
-
-
0028103275
-
The CCP4 Suite: Programs for Protein Crystallography
-
Collaborative Computational Project
-
Collaborative Computational Project (1994) The CCP4 Suite: Programs for Protein Crystallography. Acta Crystallogr. Sect. D: Biol. Crystallogr., 50, 760-763.
-
(1994)
Acta Crystallogr. Sect. D: Biol. Crystallogr
, vol.50
, pp. 760-763
-
-
-
30
-
-
0033081959
-
Discrimination of solvent from protein regions in native Fouriers as a means of evaluating heavy-atom solutions in the MIR and MAD methods
-
Terwilliger,T.C. and Berendzen,J. (1999) Discrimination of solvent from protein regions in native Fouriers as a means of evaluating heavy-atom solutions in the MIR and MAD methods. Acta Crystallogr. Sect. D: Biol. Crystallogr., 55, 501-505.
-
(1999)
Acta Crystallogr. Sect. D: Biol. Crystallogr
, vol.55
, pp. 501-505
-
-
Terwilliger, T.C.1
Berendzen, J.2
-
31
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones,T.A., Zou,J.Y., Cowan,S.W. and Kjeldgaard,M. (1991) Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. Sect. A: Found. Crystallogr., 47, 110-119.
-
(1991)
Acta Crystallogr. Sect. A: Found. Crystallogr
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
33
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brünger,A.T., Adams,P.D., Clore,G.M., DeLano,W.L., Gros,P., Grosse-Kunstleve,R.W., Jiang,J.-S., Kuszewski,J., Nilges,M., Pannu,N.S. et al. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. Sect. D: Biol. Crystallogr., 54, 905-921.
-
(1998)
Acta Crystallogr. Sect. D: Biol. Crystallogr
, vol.54
, pp. 905-921
-
-
Brünger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.-S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
35
-
-
0035191761
-
Evaluation of a Tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation
-
Bateman,B.T., Donegan,N.P., Jarry,T.M., Palma,M. and Cheung,A.L. (2001) Evaluation of a Tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation. Infect. Immun., 69, 7851-7857.
-
(2001)
Infect. Immun
, vol.69
, pp. 7851-7857
-
-
Bateman, B.T.1
Donegan, N.P.2
Jarry, T.M.3
Palma, M.4
Cheung, A.L.5
-
36
-
-
25844514282
-
Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family
-
Hong,M., Fuangthong,M., Helmann,J.D. and Brennan,R.G. (2005) Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family. Mol. Cell, 20, 131-141.
-
(2005)
Mol. Cell
, vol.20
, pp. 131-141
-
-
Hong, M.1
Fuangthong, M.2
Helmann, J.D.3
Brennan, R.G.4
-
37
-
-
36248933266
-
Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR
-
Newberry,K.J., Fuangthong,M., Panmanee,W., Mongkolsuk,S. and Brennan,R.G. (2007) Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR. Mol. Cell, 28 652-664.
-
(2007)
Mol. Cell
, vol.28
, pp. 652-664
-
-
Newberry, K.J.1
Fuangthong, M.2
Panmanee, W.3
Mongkolsuk, S.4
Brennan, R.G.5
-
39
-
-
0036468362
-
Prokaryotic transcription regulators: More than just the helix-turn-helix motif
-
Huffman,J.L. and Brennan,R.G. (2002) Prokaryotic transcription regulators: More than just the helix-turn-helix motif. Curr. Opin. Struct. Biol., 12, 98-106.
-
(2002)
Curr. Opin. Struct. Biol
, vol.12
, pp. 98-106
-
-
Huffman, J.L.1
Brennan, R.G.2
-
40
-
-
0037047395
-
Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux Operon of Pseudomonas aeruginosa
-
Lim,D., Poole,K. and Strynadka,N.C.J. (2002) Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux Operon of Pseudomonas aeruginosa. J. Biol. Chem., 277, 29253-29259.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 29253-29259
-
-
Lim, D.1
Poole, K.2
Strynadka, N.C.J.3
-
41
-
-
33745267050
-
The crystal structure of the transcriptional regulator HucR from Deinococcus radiodurans reveals a repressor preconfigured for DNA binding
-
Bordelon,T., Wilkinson,S.P., Grove,A. and Newcomer,M.E. (2006) The crystal structure of the transcriptional regulator HucR from Deinococcus radiodurans reveals a repressor preconfigured for DNA binding. J. Mol. Biol., 360, 168-177.
-
(2006)
J. Mol. Biol
, vol.360
, pp. 168-177
-
-
Bordelon, T.1
Wilkinson, S.P.2
Grove, A.3
Newcomer, M.E.4
-
42
-
-
34248524818
-
Crystal structure of an archaeal homologue of multidrug resistance repressor protein, EmrR, from hyperthermophilic archaea Sulfolobus tokodaii strain 7
-
Miyazono,K., Tsujimura,M., Kawarabayasi,Y. and Tanokura,M. (2007) Crystal structure of an archaeal homologue of multidrug resistance repressor protein, EmrR, from hyperthermophilic archaea Sulfolobus tokodaii strain 7. Proteins: Struct. Funct. Bioinform., 67, 1138-1146.
-
(2007)
Proteins: Struct. Funct. Bioinform
, vol.67
, pp. 1138-1146
-
-
Miyazono, K.1
Tsujimura, M.2
Kawarabayasi, Y.3
Tanokura, M.4
-
43
-
-
0034107895
-
Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding
-
Alekshun,M.N., Kim,Y.S. and Levy,S.B. (2000) Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding. Mol. Microbiol., 35, 1394-1404.
-
(2000)
Mol. Microbiol
, vol.35
, pp. 1394-1404
-
-
Alekshun, M.N.1
Kim, Y.S.2
Levy, S.B.3
-
44
-
-
54449100560
-
The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR
-
Wilke,M.S., Heller,M., Creagh,L.A., Haynes,C.A., McIntosh,L.P., Poole,K. and Strynadka,N.C.J. (2008) The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR. Proc. Natl Acad. Sci., 105, 14832-14837.
-
(2008)
Proc. Natl Acad. Sci
, vol.105
, pp. 14832-14837
-
-
Wilke, M.S.1
Heller, M.2
Creagh, L.A.3
Haynes, C.A.4
McIntosh, L.P.5
Poole, K.6
Strynadka, N.C.J.7
-
45
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson,J.D., Higgins,D.G. and Gibson,T.J. (1994) CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res., 22, 4673-4680.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
46
-
-
35948985469
-
Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus
-
DeMarco,C.E., Cushing,L.A., Frempong-Manso,E., Seo,S.M., Jaravaza,T.A. and Kaatz,G.W. (2007) Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus. Antimicrob. Agents Chemother., 51, 3235-3239.
-
(2007)
Antimicrob. Agents Chemother
, vol.51
, pp. 3235-3239
-
-
DeMarco, C.E.1
Cushing, L.A.2
Frempong-Manso, E.3
Seo, S.M.4
Jaravaza, T.A.5
Kaatz, G.W.6
|