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Volumn 50, Issue 4, 2006, Pages 1276-1281

MepR, a represser of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; REGULATOR PROTEIN; BACTERIAL PROTEIN; REPRESSOR PROTEIN;

EID: 33645756567     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.50.4.1276-1281.2006     Document Type: Article
Times cited : (72)

References (24)
  • 1
    • 0028104421 scopus 로고
    • A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates
    • Ahmed, M., C. M. Borsch, S. S. Taylor, N. Vazquez-Laslop, and A. A. Neyfakh. 1994. A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates. J. Biol. Chem. 269: 2S506-2S513.
    • (1994) J. Biol. Chem. , vol.269
    • Ahmed, M.1    Borsch, C.M.2    Taylor, S.S.3    Vazquez-Laslop, N.4    Neyfakh, A.A.5
  • 2
    • 0034887133 scopus 로고    scopus 로고
    • The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Å resolution
    • Alekshun, M. N., S. B. Levy, T. R. Mealy, B. A. Seaton, and J. F. Head. 2001. The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Å resolution. Nat. Struct. Biol. 8:710-714.
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 710-714
    • Alekshun, M.N.1    Levy, S.B.2    Mealy, T.R.3    Seaton, B.A.4    Head, J.F.5
  • 3
    • 0035191761 scopus 로고    scopus 로고
    • Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation
    • Bateman, B. T., N. P. Donegan, T. M. Jarry, M. Palma, and A. L. Cheung. 2001. Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation. Infect. Immun. 69:7851-7857.
    • (2001) Infect. Immun. , vol.69 , pp. 7851-7857
    • Bateman, B.T.1    Donegan, N.P.2    Jarry, T.M.3    Palma, M.4    Cheung, A.L.5
  • 4
    • 0346887115 scopus 로고    scopus 로고
    • Structure and function of efflux pumps that confer resistance to drugs
    • Borges-Walmsley, I. M., K. S. McKeegan, and A. R. Walmsley. 2003. Structure and function of efflux pumps that confer resistance to drugs. Biochem. J. 376:313-338.
    • (2003) Biochem. J. , vol.376 , pp. 313-338
    • Borges-Walmsley, I.M.1    McKeegan, K.S.2    Walmsley, A.R.3
  • 5
    • 77956693877 scopus 로고    scopus 로고
    • Molecular genetic analysis of staphylococcal virulence
    • Foster, T. J. 1998. Molecular genetic analysis of staphylococcal virulence. Methods Microbiol. 27:433-454.
    • (1998) Methods Microbiol. , vol.27 , pp. 433-454
    • Foster, T.J.1
  • 6
    • 0032541162 scopus 로고    scopus 로고
    • QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA
    • Grkovic, S., M. H. Brown, N. J. Roberts, I. T. Paulsen, and R. A. Skurray. 1998. QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA. J. Biol. Chem. 273:18665-18673.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18665-18673
    • Grkovic, S.1    Brown, M.H.2    Roberts, N.J.3    Paulsen, I.T.4    Skurray, R.A.5
  • 8
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 9
    • 0036771636 scopus 로고    scopus 로고
    • Bmodulates virulence determinant expression and stress resistance: Characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4
    • Bmodulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J. Bacteriol. 184:5457-5467.
    • (2002) J. Bacteriol. , vol.184 , pp. 5457-5467
    • Horsburgh, M.J.1    Aish, J.L.2    White, I.J.3    Shaw, L.4    Lithgow, J.K.5    Foster, S.J.6
  • 10
    • 18244388696 scopus 로고    scopus 로고
    • Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein
    • Kaatz, G. W., F. McAleese, and S. M. Seo. 2005. Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. Antimicrob. Agents Chemother. 49: 1857-1864.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1857-1864
    • Kaatz, G.W.1    McAleese, F.2    Seo, S.M.3
  • 11
    • 4444327371 scopus 로고    scopus 로고
    • Effect of substrate exposure and other growth condition manipulations on norA expression
    • Kaatz, G. W., and S. M. Seo. 2004. Effect of substrate exposure and other growth condition manipulations on norA expression. J. Antimicrob. Chemother. 54:364-369.
    • (2004) J. Antimicrob. Chemother. , vol.54 , pp. 364-369
    • Kaatz, G.W.1    Seo, S.M.2
  • 12
    • 11244324384 scopus 로고    scopus 로고
    • Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter
    • Kaatz, G. W., R. V. Thyagarajan, and S. M. Seo. 2005. Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter. Antimicrob. Agents Chemother. 49:161-169.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 161-169
    • Kaatz, G.W.1    Thyagarajan, R.V.2    Seo, S.M.3
  • 13
    • 0025814707 scopus 로고
    • Analysis of transcriptional control of the gerD spore germination gene of Bacillus subtilis 168
    • Kemp, E. H., R. L. Sammons, A. Moir, D. Sun, and P. Setlow. 1991. Analysis of transcriptional control of the gerD spore germination gene of Bacillus subtilis 168. J. Bacteriol. 173:4646-4652.
    • (1991) J. Bacteriol. , vol.173 , pp. 4646-4652
    • Kemp, E.H.1    Sammons, R.L.2    Moir, A.3    Sun, D.4    Setlow, P.5
  • 15
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli. U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 16
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: Causes, challenges, and responses
    • Levy, S. B., and B. Marshall. 2004. Antibacterial resistance worldwide: causes, challenges, and responses. Nat. Med. 10:8122-8129.
    • (2004) Nat. Med. , vol.10 , pp. 8122-8129
    • Levy, S.B.1    Marshall, B.2
  • 17
    • 0029079304 scopus 로고
    • Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences
    • Martin, R. G., and J. L. Rosner. 1995. Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences. Proc. Natl. Acad. Sci. USA 92:5456-5460.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5456-5460
    • Martin, R.G.1    Rosner, J.L.2
  • 18
    • 18244403495 scopus 로고    scopus 로고
    • A novel MATE family effiux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline
    • McAleese, F., P. Petersen, A. Ruzin, P. M. Dunman, E. Murphy, S. J. Projan, and P. A. Bradford. 2005. A novel MATE family effiux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline. Antimicrob. Agents Chemother. 49:1865-1871.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1865-1871
    • McAleese, F.1    Petersen, P.2    Ruzin, A.3    Dunman, P.M.4    Murphy, E.5    Projan, S.J.6    Bradford, P.A.7
  • 19
    • 0014127769 scopus 로고
    • Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus
    • Novick, R. 1967. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology 33:155-166.
    • (1967) Virology , vol.33 , pp. 155-166
    • Novick, R.1
  • 23
    • 0038643232 scopus 로고    scopus 로고
    • Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus
    • Truong-Bolduc, Q.-C., X. Zhang, and D. C. Hooper. 2003. Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus. J. Bacteriol. 185:3127-3138.
    • (2003) J. Bacteriol. , vol.185 , pp. 3127-3138
    • Truong-Bolduc, Q.-C.1    Zhang, X.2    Hooper, D.C.3
  • 24
    • 0035905808 scopus 로고    scopus 로고
    • Crystal structure of the transcription activator BmrR bound to DNA and a drug
    • Zheleznova-Heldwein, E. E., and R. G. Brennan. 2001. Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature 409: 378-382.
    • (2001) Nature , vol.409 , pp. 378-382
    • Zheleznova-Heldwein, E.E.1    Brennan, R.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.