Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 1941-1951

  Roy, Kunal ^a   Roy, Partha Pratim ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Cytochrome P450 enzymes; G PLS; GFA; QAAR; QSAR

Indexed keywords

CYTOCHROME P450 2A5; CYTOCHROME P450 2A6; NAPHTHALENE DERIVATIVE; QUINOLINE; TETRALIN DERIVATIVE;

ANALYTIC METHOD; ARTICLE; CHEMOMETRIC ANALYSIS; DRUG ACTIVITY; DRUG INHIBITION; ELECTRONICS; GENETIC FUNCTION APPROXIMATION; HYDROPHOBICITY; LIPOPHILICITY; PARTIAL LEAST SQUARES REGRESSION; PREDICTION; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RANDOMIZATION; THERMODYNAMICS; VALIDATION STUDY;

ARYL HYDROCARBON HYDROXYLASES; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 62549093519     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.11.010     Document Type: Article

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