Psoralen-lnduced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner

Molecular Pharmacology

Volumn 75, Issue 3, 2009, Pages 599-607

  Derheimer, Frederick A ^a,b   Hicks, J Kevin ^c   Paulsen, Michelle T ^a   Canman, Christine E ^c   Ljungman, Mats ^a,c,d  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE RAD3; NUCLEIC ACID BINDING PROTEIN; PHOSPHOTRANSFERASE; PROTEIN P53; PSORALEN; SERINE; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN; XERODERMA PIGMENTOSUM GROUP F PROTEIN; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; CROSS LINKING REAGENT; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; CARCINOGENESIS; CELL CYCLE S PHASE; COCKAYNE SYNDROME; CONTROLLED STUDY; DNA CROSS LINKING; DNA REPLICATION; FANCONI ANEMIA; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PUVA; SKIN CANCER; SKIN FIBROBLAST; XERODERMA PIGMENTOSUM; BIOSYNTHESIS; CELL LINE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DNA DAMAGE; DRUG EFFECT; FIBROBLAST; GENETICS; PHYSIOLOGY; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ATAXIA TELANGIECTASIA; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; CROSS-LINKING REAGENTS; DNA DAMAGE; FIBROBLASTS; FICUSIN; HUMANS; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 62149111100     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.051698     Document Type: Article

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