메뉴 건너뛰기




Volumn 10, Issue 3, 1999, Pages 155-162

Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; DACTINOMYCIN; PROTEIN P53; TRANSCRIPTION FACTOR E2F;

EID: 0033059183     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (45)

References (54)
  • 1
    • 0028880855 scopus 로고
    • Cyclins, cyclin-dependent kinases and Cdk inhibitors: Implications in cell cycle control and cancer
    • MacLachland, T., Sang, N., and Giordano, A. Cyclins, cyclin-dependent kinases and Cdk inhibitors: implications in cell cycle control and cancer. Crit. Rev. Eukaryotic Gene Expr., 5: 127-156, 1995.
    • (1995) Crit. Rev. Eukaryotic Gene Expr. , vol.5 , pp. 127-156
    • MacLachland, T.1    Sang, N.2    Giordano, A.3
  • 2
    • 0026526437 scopus 로고
    • A link between the Rb tumor suppressor protein and viral oncoproteins
    • Washington DC
    • Nevins, J. A link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.1
  • 3
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 4
    • 0031815596 scopus 로고    scopus 로고
    • Toward an understanding of the functional complexity of the E2F and retinoblastoma families
    • Nevins, J. R. Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ., 9: 585-593, 1998.
    • (1998) Cell Growth Differ. , vol.9 , pp. 585-593
    • Nevins, J.R.1
  • 5
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson, N. The regulation of E2F by pRB-family proteins. Genes Dev., 12: 2245-2262, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 6
    • 0032484989 scopus 로고    scopus 로고
    • Retinoblastoma protein recruits histone deacetylase to repress transcription
    • Brehm, A., Miska, E., McCance, D., Reid, J., Bannister, A., and Kouzarides, T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (Lond.), 391: 597-601, 1998.
    • (1998) Nature (Lond.) , vol.391 , pp. 597-601
    • Brehm, A.1    Miska, E.2    McCance, D.3    Reid, J.4    Bannister, A.5    Kouzarides, T.6
  • 8
    • 0032549001 scopus 로고    scopus 로고
    • RB interacts with histone deacetylase to repress transcription
    • Luo, R., Postigo, A., and Dean, D. RB interacts with histone deacetylase to repress transcription. Cell, 92: 463-473, 1998.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.1    Postigo, A.2    Dean, D.3
  • 9
  • 10
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 11
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia, A., and Kastan, M. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev., 12: 2973-2983, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 2973-2983
    • Giaccia, A.1    Kastan, M.2
  • 13
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S., Plunkett, B., Walsh, V., and Kastan, M. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.1    Plunkett, B.2    Walsh, V.3    Kastan, M.4
  • 16
    • 0020066520 scopus 로고
    • Failure of RNA synthesis to recover after UV-irradiation: An early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum
    • Mayne, L., and Lehmann, A. Failure of RNA synthesis to recover after UV-irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum. Cancer Res., 42: 1473-1478, 1982.
    • (1982) Cancer Res. , vol.42 , pp. 1473-1478
    • Mayne, L.1    Lehmann, A.2
  • 17
    • 0029785723 scopus 로고    scopus 로고
    • Blockage of RNA polymerase as a possible trigger for UV light-induced apoptosis
    • Ljungman, M., and Zhang, F. Blockage of RNA polymerase as a possible trigger for UV light-induced apoptosis. Oncogene, 13: 823-831, 1996.
    • (1996) Oncogene , vol.13 , pp. 823-831
    • Ljungman, M.1    Zhang, F.2
  • 18
    • 0033590624 scopus 로고    scopus 로고
    • Inhibition of RNA polymerase ii as a trigger for the p53 response
    • Ljungman, M., Zhang, F., Chen, F., Rainbow, A., and McKay, B. Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene, 18: 583-592, 1999.
    • (1999) Oncogene , vol.18 , pp. 583-592
    • Ljungman, M.1    Zhang, F.2    Chen, F.3    Rainbow, A.4    McKay, B.5
  • 19
    • 0029788135 scopus 로고    scopus 로고
    • Discordance between accumulated p53 protein level and its transcriptional activity in response to uv radiation
    • Lu, X., Burbidge, S. A., Griffin, S., and Smith, H. M. Discordance between accumulated p53 protein level and its transcriptional activity in response to uv radiation. Oncogene, 13: 413-418, 1996.
    • (1996) Oncogene , vol.13 , pp. 413-418
    • Lu, X.1    Burbidge, S.A.2    Griffin, S.3    Smith, H.M.4
  • 20
    • 0030748598 scopus 로고    scopus 로고
    • Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest
    • Reinke, V., and Lozano, G. Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest. Radiat Res., 148: 115-122, 1997.
    • (1997) Radiat Res. , vol.148 , pp. 115-122
    • Reinke, V.1    Lozano, G.2
  • 21
    • 0032490853 scopus 로고    scopus 로고
    • waf1 and bax expression: Implications for DMA repair, UV sensitivity and the induction of apoptosis
    • waf1 and bax expression: implications for DMA repair, UV sensitivity and the induction of apoptosis. Oncogene, 17: 545-555, 1998.
    • (1998) Oncogene , vol.17 , pp. 545-555
    • McKay, B.C.1    Ljungman, M.2    Rainbow, A.J.3
  • 23
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage
    • Smith, M. L., Chen, I. T., Zhan, Q. M., O'Connor, P. M., and Fornace, A. J., Jr. Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene, 10: 1053-1059, 1995.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.M.3    O'Connor, P.M.4    Fornace A.J., Jr.5
  • 24
    • 0025639158 scopus 로고
    • The e6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., Werness, B., Huibregtse, J., Levine, A., and Howley, P. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 1129-1136, 1990.
    • (1990) Cell , pp. 1129-1136
    • Scheffner, M.1    Werness, B.2    Huibregtse, J.3    Levine, A.4    Howley, P.5
  • 25
    • 0029315367 scopus 로고
    • Human papillomavirus e6 and e7: Proteins which deregulate the cell cycle
    • Tommasino, M., and Crawford, L. Human papillomavirus E6 and E7: proteins which deregulate the cell cycle. BioEssays, 17: 509-518, 1995.
    • (1995) BioEssays , vol.17 , pp. 509-518
    • Tommasino, M.1    Crawford, L.2
  • 26
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan, Q., Carrier, F., and Fornace, A. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol., 13: 4242-4250, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fornace, A.3
  • 27
    • 0031909865 scopus 로고    scopus 로고
    • Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system
    • Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system. Mol. Cell. Biol., 18: 1400-1407, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1400-1407
    • Gorospe, M.1    Wang, X.T.2    Holbrook, N.J.3
  • 28
    • 0030871776 scopus 로고    scopus 로고
    • P53-dependent p21 induction following γ-irradiation without concomitant p53 induction in a human peripheral neuroepithelioma cell line
    • Isaacs, J. S., Chiao, C., Merrick, B. A., Selkirk, J. K., Barrett, J. C., and Weissman, B. E. p53-dependent p21 induction following γ-irradiation without concomitant p53 induction in a human peripheral neuroepithelioma cell line. Cancer Res., 57: 2986-2992, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2986-2992
    • Isaacs, J.S.1    Chiao, C.2    Merrick, B.A.3    Selkirk, J.K.4    Barrett, J.C.5    Weissman, B.E.6
  • 32
    • 0032080424 scopus 로고    scopus 로고
    • P53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts
    • Cistulli, C., and Kaufmann, W. p53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts. Cancer Res., 58: 1993-2002, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 1993-2002
    • Cistulli, C.1    Kaufmann, W.2
  • 33
    • 0031263412 scopus 로고    scopus 로고
    • Capacity of UV-irradiated human fibroblasts to support adenovirus DNA synthesis correlates with transcription-coupled repair and is reduced in SV40-transformed cells and cells expressing mutant p53
    • McKay, B. C., Winrow, C., and Rainbow, A. J. Capacity of UV-irradiated human fibroblasts to support adenovirus DNA synthesis correlates with transcription-coupled repair and is reduced in SV40-transformed cells and cells expressing mutant p53. Photochem. Photobiol., 66: 659-664, 1997.
    • (1997) Photochem. Photobiol. , vol.66 , pp. 659-664
    • McKay, B.C.1    Winrow, C.2    Rainbow, A.J.3
  • 34
    • 0031416522 scopus 로고    scopus 로고
    • Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene
    • Lond.
    • McKay, B. C., Francis, M. A., and Rainbow, A. J. Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene. Carcinogenesis (Lond.), 18: 245-249, 1997.
    • (1997) Carcinogenesis , vol.18 , pp. 245-249
    • McKay, B.C.1    Francis, M.A.2    Rainbow, A.J.3
  • 35
    • 0029029741 scopus 로고
    • Li-fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance
    • Ford, J. M., and Hanawalt, P. C. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc. Natl. Acad. Sci. USA, 92: 8876-8880, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8876-8880
    • Ford, J.M.1    Hanawalt, P.C.2
  • 36
    • 0030853074 scopus 로고    scopus 로고
    • Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in uv-irradiated human fibroblasts
    • Ford, J. M., and Hanawalt, P. C. Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J. Biol. Chem, 272: 28073-28080, 1997.
    • (1997) J. Biol. Chem , vol.272 , pp. 28073-28080
    • Ford, J.M.1    Hanawalt, P.C.2
  • 40
    • 0028238420 scopus 로고
    • Effect of uv-irradiation on cell cycle, viability and the expression of p53, gadd153, and gadd45 genes in normal and hpv-immortalized human oral keratinocytes
    • Gujuluva, C., Baek, J-H., Shin, K-H., Cherrick, H., and Park, N-H. Effect of UV-irradiation on cell cycle, viability and the expression of p53, gadd153, and gadd45 genes in normal and HPV-immortalized human oral keratinocytes. Oncogene, 9: 1819-1827, 1994.
    • (1994) Oncogene , vol.9 , pp. 1819-1827
    • Gujuluva, C.1    Baek, J.-H.2    Shin, K.-H.3    Cherrick, H.4    Park, N.-H.5
  • 41
    • 0029960486 scopus 로고    scopus 로고
    • Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation
    • Zhan, Q. M., Fan, S. J., Smith, M. L., Bae, I., Yu, K., Alamo, I., O'Connor, P. M., and Fornace, A. J. Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation. DNA Cell Biol., 15: 805-815, 1996.
    • (1996) DNA Cell Biol. , vol.15 , pp. 805-815
    • Zhan, Q.M.1    Fan, S.J.2    Smith, M.L.3    Bae, I.4    Yu, K.5    Alamo, I.6    O'Connor, P.M.7    Fornace, A.J.8
  • 42
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation - Defects in chromosome instability syndromes?
    • Lu, X., and Lane, D. P. Differential induction of transcriptionally active p53 following UV or ionizing radiation - defects in chromosome instability syndromes? Cell, 75: 765-778, 1993.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 43
    • 0027143217 scopus 로고
    • The mdm-2 gene is induced in response to UV light in a p53-dependent manner
    • Perry, M., Piette, J., Zawadzki, J., Harvey, D., and Levine, A. The mdm-2 gene is induced in response to UV light in a p53-dependent manner. Proc. Natl. Acad. Sci. USA, 90: 11623-11627, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11623-11627
    • Perry, M.1    Piette, J.2    Zawadzki, J.3    Harvey, D.4    Levine, A.5
  • 44
    • 0023936042 scopus 로고
    • Inhibition of transcription in eukaryotic cells by X-irradiation: Relation to the loss of topological constraint in closed DNA loops
    • Luchnik, A. N., Hisamutdinov, T. A., and Georgiev, P. A. Inhibition of transcription in eukaryotic cells by X-irradiation: relation to the loss of topological constraint in closed DNA loops. Nucleic Acids Res., 16: 5175-5190, 1988.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 5175-5190
    • Luchnik, A.N.1    Hisamutdinov, T.A.2    Georgiev, P.A.3
  • 45
    • 0024445799 scopus 로고
    • Structure of transcriptionally active chromatin: Radiological evidence for requirement of torsionally constrained DNA
    • Rodi, C., and Sauerbier, W. Structure of transcriptionally active chromatin: radiological evidence for requirement of torsionally constrained DNA. J. Cell. Physiol., 141: 346-352, 1989.
    • (1989) J. Cell. Physiol. , vol.141 , pp. 346-352
    • Rodi, C.1    Sauerbier, W.2
  • 46
    • 0014859062 scopus 로고
    • Inhibition of RNA synthesis by actinomycin d: Characteristic dose-response of different rna species
    • Perry, R., and Kelley, D. Inhibition of RNA synthesis by actinomycin D: characteristic dose-response of different RNA species. J. Cell. Physiol., 76: 127-140, 1970.
    • (1970) J. Cell. Physiol. , vol.76 , pp. 127-140
    • Perry, R.1    Kelley, D.2
  • 47
    • 0029133264 scopus 로고
    • Cell cycle dependent effects of uv-radiation on p53 expression and retinoblastoma protein phosphorylation
    • Haapajarvi, T., Kivinen, L., Pitkanen, K., and Laiho, M. Cell cycle dependent effects of uv-radiation on p53 expression and retinoblastoma protein phosphorylation. Oncogene, 11: 151-159, 1995.
    • (1995) Oncogene , vol.11 , pp. 151-159
    • Haapajarvi, T.1    Kivinen, L.2    Pitkanen, K.3    Laiho, M.4
  • 48
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • Demers, G., Foster, S., Halbert, C. L., and Galloway, D. Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc. Natl. Acad. Sci. USA, 91: 4382-4386, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4382-4386
    • Demers, G.1    Foster, S.2    Halbert, C.L.3    Galloway, D.4
  • 49
    • 0029847666 scopus 로고    scopus 로고
    • Inhibition of retinoblastoma protein translation by UVB in human melanocytic cells and reduced cell cycle arrest following repeated irradiation
    • Pedley, J., Ablett, E., Pettit, A., Meyer, J., Dunn, I., Sturm, R., and Parsons, P. Inhibition of retinoblastoma protein translation by UVB in human melanocytic cells and reduced cell cycle arrest following repeated irradiation. Oncogene, 13: 1335, 1996.
    • (1996) Oncogene , vol.13 , pp. 1335
    • Pedley, J.1    Ablett, E.2    Pettit, A.3    Meyer, J.4    Dunn, I.5    Sturm, R.6    Parsons, P.7
  • 50
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • Leone, G., DeGregori, J., Sears, R., Jakoi, L., and Nevins, J. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature (Lond.), 387: 422-426, 1997.
    • (1997) Nature (Lond.) , vol.387 , pp. 422-426
    • Leone, G.1    DeGregori, J.2    Sears, R.3    Jakoi, L.4    Nevins, J.5
  • 51
    • 0023873887 scopus 로고
    • Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells
    • Ronai, Z., Okin, E., and Weinstein, I. Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells. Oncogene, 2: 201-204, 1988.
    • (1988) Oncogene , vol.2 , pp. 201-204
    • Ronai, Z.1    Okin, E.2    Weinstein, I.3
  • 52
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Washington DC
    • Baker, S., Markowitz, S., Fearon, E., Wilson, J., and Vogelstein, B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (Washington DC), 249: 912-915, 1990.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.1    Markowitz, S.2    Fearon, E.3    Wilson, J.4    Vogelstein, B.5
  • 53
    • 0028607435 scopus 로고
    • Identification of a human ubiquitin-conjugating enzyme that mediates the e6-ap-dependent ubiquitination of p53
    • Scheffner, M., Huibregtse, J. M., and Howley, P. M. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc. Natl. Acad. Sci. USA, 91: 8797-8801, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8797-8801
    • Scheffner, M.1    Huibregtse, J.M.2    Howley, P.M.3
  • 54
    • 0024398561 scopus 로고
    • Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): Critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histogram
    • Hoy, C., Seamer, L., and Schimke, R. Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histogram. Cytometry, 10: 718-725, 1989.
    • (1989) Cytometry , vol.10 , pp. 718-725
    • Hoy, C.1    Seamer, L.2    Schimke, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.