Stabilization effect of resin on the production of potent proteasome inhibitor NPI-0052 during submerged fermentation of Salinispora tropica

Journal of Antibiotics

Volumn 60, Issue 7, 2007, Pages 469-472

  Tsueng, Ginger ^a   Lam, Kin S ^a  

^a Nereus Pharmaceuticals Inc   (United States)

Author keywords

Amberlite XAD 7 resin; NPI 0052; Proteasome inhibitor; Salinispora tropica

Indexed keywords

ACRYLIC ACID RESIN; ANTIBIOTIC AGENT; POLACRILIN; PROTEASOME INHIBITOR; RESIN; SALINOSPORAMIDE A; AMBERLITE XAD 7; ANION EXCHANGE RESIN; LACTONE; POLYSTYRENE DERIVATIVE; PROTEASOME; PROTEINASE INHIBITOR; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; DRUG STRUCTURE; FERMENTATION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; SALINISPORA TROPICA; SUBMERGED FERMENTATION; APOPTOSIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; METABOLISM; MICROMONOSPORACEAE;

SALINISPORA TROPICA;

ACRYLIC RESINS; ANION EXCHANGE RESINS; APOPTOSIS; FERMENTATION; HUMANS; LACTONES; MICROMONOSPORACEAE; POLYSTYRENES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRROLES;

EID: 38449101286     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.61     Document Type: Article

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