Copper & biological health

Indian Journal of Medical Research

Volumn 128, Issue 4, 2008, Pages 448-461

  Krupanidhi, Srirama ^a   Sreekumar, Arun ^b   Sanjeevi, C B ^c  

^a SRI SATHYA SAI INSTITUTE OF HIGHER LEARNING   (India)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ceruloplasmin; Cu carriers; Cu chaperones; Cu chelators; Cu metabolism; Cu transporters; Menkes disease; Oxygen binding Cu proteins; Wilson's disease

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMYLOID PRECURSOR PROTEIN; CARRIER PROTEIN; CHAPERONE; COPPER; GLUTATHIONE; MONOPHENOL MONOOXYGENASE; PENICILLAMINE; PRION PROTEIN; PROTEIN COPT; PROTEIN COPY; PROTEIN COPZ; PROTEIN CTR1; REPRESSOR PROTEIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANGIOGENESIS; BIOAVAILABILITY; CHELATION THERAPY; COPPER DEFICIENCY; COPPER METABOLISM; COPPER TRANSPORT; DIETARY INTAKE; ENDOCYTOSIS; ENDOTHELIUM CELL; HOMEOPATHY; HUMAN; ION TRANSPORT; MENKES SYNDROME; METAL BINDING; NONHUMAN; OXYGENATION; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SCRAPIE; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; WILSON DISEASE;

BIOLOGICAL TRANSPORT; COPPER; HOMEOSTASIS; HUMANS;

EID: 61849184307     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Review

References (81)

1. Aaseth J, Flaten TP, Andersen O. Hereditary iron and copper deposition: diagnostics, pathogenesis and therapeutics. Scand J Gastroenterol 2007; 42: 673-81.
2. Araya M, Pizarro F, Olivares M, Arredondo M, Gonzalez M, Mendez M. Understanding copper homeostasis in humans and copper effects on health. Biol Res 2006; 39: 183-7.
3. Decker H, Terwilliger N. Cops and robbers: putative evolution of copper oxygen-binding proteins. J Exp Biol 2000; 203: 1777-82.
4. Goodman VL, Brewer GJ, Merajver SD. Copper deficiency as an anti-cancer strategy. Endocr Relat Cancer 2004; 11: 255-63.
5. Srivastava S, Singh BR, Tripathi VN Application of bacterial biomass as a potential metal indicator. Curr Sci 2005; 89: 1248-51.
6. Wapnir RA. Copper absorption and bioavailability. Am J Clin Nutr 1998; 67: 1054S-60S.
7. Baker DH, Czarnecki-Maulden GL. Pharmacologic role of cysteine in ameliorating or exacerbating mineral toxicities. J Nutr 1987; 117: 1003-10.
8. Pott EB, Henry PR, Ammerman CB, Merritt AM, Madison JB, Miles RD. Relative bioavailability of Cu in a Cu-lysine complex for chicks and lambs. Anim Feed Sci Technol 1994; 45: 193-203.
9. Kincaid RL, Blauwiekel RM, Cronath JD. Supplementation of Cu sulphate or Cu proteinate for growing calves fed forages containing molybdenum. J Diary Sci 1986; 69: 160-3.
10. Lowndes SA, Harris AL. The role of copper in tumour angiogenesis. J Mammary Gland Biol Neoplasia 2005; 10: 299-310.
11. Gu M, Cooper JM, Butler P, Walker AP, Mistry PK, Dooley JS, et al. Oxidative-phosphorylation defects in liver of patients with Wilson's disease. Lancet 2000; 356: 469-74.
12. Krupanidhi S. Respiratory pigments. Biol Educ (India) 1988; 4: 104-14.
13. Krupanidhi S, Laksmikanth T. Detection of haemocyanin in native PAGE gels. Natl Acad Sci Lett 2005; 28: 353-5.
14. Krupanidhi S, Venkata Reddy V, Padmanabha Naidu B. Some studies on copper metabolism in the garden snail, Cryptozona ligulata. Indian J Exp Biol 1978; 16: 249-50.
15. Krupanidhi S. Copper granules in the hepatopancreas of the snail, Crytpzona ligulata. Curr Sci 1985; 53: 431-2.
16. van Holde KE, Miller KI. Hemocyanins. Adv Protein Chem 1995; 47: 1-81.
17. Brown NL, Camakaris J, Lee BT, Williams T, Morby AP, Parkhill J, et al. Bacterial resistances to mercury and copper. Cell Biochem 1991; 46: 106-14.
18. Rouch DLB, Camakaris J. Metal on homeostasis: Molecular biology and chemistry. Supplement: UCLA Symposia on Molecular & Cellular Biology 1989; 38: 439-46.
19. Grotz N, Guerinot ML. Molecular aspects of Cu, Fe and Zn homeostasis in plants. Biochim Biophys Acta 2006; 1763: 595-608.
20. Sancenon V, Puig S, Mira H, Thiele DJ, Penarrubia L. Identification of a copper transporter family in Arabidopsis thaliana. Plant Mol Biol 2003; 51: 577-87.
21. Petris MJ. The SLC31 (Ctr) copper transporter family. Pflugers Arch 2004; 447: 752-5.
22. Chelly J, Tumer Z, Tonnesen T, Petterson A, Ishikawa-Brush Y, Tommerup N, et al. Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein. Nat Genet 1993; 3: 14-9.
23. Mercer JF, Livingston J, Hall B, Paynter JA, Begy C, Chandrasekharappa S, et al. Isolation of a partial candidate gene for Menkes disease by positional cloning. Nat Genet 1993; 3: 20-5.
24. Mufti AR, Burstein E, Duckett CS. XIAP: cell death regulation meets copper homeostasis. Arch Biochem Biophys 2007; 463:168-74.
25. La Fontaine S, Mercer JF. Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis. Arch Biochem Biophys 2007; 463: 149-67.
26. Ackland ML, Anikijenko P, Michalczyk A, Mercer JF. Expression of menkes copper-transporting ATPase, MNK, in the lactating human breast: possible role in copper transport into milk. J Histochem Cytochem 1999; 47: 1553-62.
27. Guo Y, Smith K, Lee J, Thiele DJ, Petris MJ. Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter. J Biol Chem 2004; 279: 17428-33.
28. van De Sluis B, Rothuizen J, Pearson PL, van Oost BA, Wijmenga C. Identification of a new copper metabolism gene by positional cloning in a purebred dog population. Hum Mol Genet 2002; 11: 165-73.
29. Klomp AE, van de Sluis B, Klomp LW, Wijmenga C. The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis. J Hepatol 2003; 39: 703-9.
30. de Bie P, van de Sluis B, Klomp L, Wijmenga C. The many faces of the copper metabolism protein MURR1/COMMD1. J Hered 2005; 96: 803-11.
31. Wimmer R, Dameron CT, Solioz M. Molecular hardware of Cu homeostasis in Enterococcus hirae. Handbook of Cu pharamacology and toxicology. Tofowa, NJ: Humana Press; 2002. p. 527-43.
32. Odermatt A, Krapf R, Solioz M. Induction of the putative copper ATPases, CopA and CopB, of Enterococcus hirae by Ag+ and Cu2+, and Ag+ extrusion by CopB. Biochem Biophys Res Commun 1994; 202: 44-8.
33. Wunderli-Ye H, Solioz M. Effects of promoter mutations on the in vivo regulation of the cop operon of Enterococcus hirae by copper(I) and copper(II). Biochem Biophys Res Commun 1999; 259: 443-9.
34. Gajiwala KS, Burley SK. Winged helix proteins. Curr Opin Struct Biol 2000; 10: 110-6.
35. Magnani D, Solioz M. Copper chaperone cycling and degradation in the regulation of the cop operon of Enterococcus hirae. Biometals 2005; 18: 407-12.
36. Portmann R, Magnani D, Stoyanov JV, Schmechel A, Multhaup G, Solioz M. Interaction kinetics of the copperresponsive CopY repressor with the cop promoter of Enterococcus hirae. J Biol Inorg Chem 2004; 9: 396-402.
37. Rhodes DR, Kalyana-Sundaram S, Tomlins SA, Mahavisno V, Kasper N, Varambally R, et al. Molecular concepts analysis links tumors, pathways, mechanisms, and drugs. Neoplasia 2007; 9: 443-54.
38. Tomlins SA, Mehra R, Rhodes DR, Cao X, Wang L, Dhanasekaran SM, et al. Integrative molecular concept modeling of prostate cancer progression. Nature Genet 2007; 39: 41-51.
39. Prohaska JR, Gybina AA. Intracellular copper transport in mammals. J Nutr 2004; 134: 1003-6.
40. Wong PC, Waggoner D, Subramaniam JR, Tessarollo L, Bartnikas TB, Culotta VC, et al. Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc Natl Acad Sci USA 2000; 97: 2886-91.
41. Coyle P, Philcox JC, Carey LC, Rofe AM. Metallothionein: the multipurpose protein. Cell Mol Life Sci 2002; 59: 627-47.
42. Hamza I, Faisst A, Prohaska J, Chen J, Gruss P, Gitlin JD. The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis. Proc Natl Acad Sci USA 2001; 98: 6848-52.
43. White AR, Reyes R, Mercer JF, Camakaris J, Zheng H, Bush AI, et al. Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Res 1999; 842: 439-44.
44. Zatta P, Frank A. Copper deficiency and neurological disorders in man and animals. Brain Res Rev 2007; 54: 19-33.
45. Daniel KG, Harbach RH, Guida WC, Dou QP. Copper storage diseases: Menkes, Wilsons, and cancer. Front Biosci 2004; 9: 2652-62.
46. Gu YH, Kodama H, Sato E, Mochizuki D, Yanagawa Y, Takayanagi M, et al. Prenatal diagnosis of Menkes disease by genetic analysis and copper measurement. Brain Dev 2002; 24: 715-8.
47. Menkes JH. Kinky hair disease: twenty five years later. Brain Dev 1988; 10: 77-9.
48. Horn N. Menkes' X-linked disease: prenatal diagnosis and carrier detection. J Inherit Metab Dis 1983; 6 (Suppl 1): 59-62.
49. Shim H, Harris ZL. Genetic defects in copper metabolism. J Nutr 2003; 133: 1527S-31S.
50. Sarkar B. Treatment of Wilson and menkes diseases. Chem Rev 1999; 99: 2535-44.
51. Underwood EJ, Suttle NF. Cu. The mineral nutrition of livestock. 3rd ed. New York: CABI Publsihing Oxon; 2001. p. 283-342.
52. Prohaska JR. Genetic diseases of copper metabolism. Clin Physiol Biochem 1986; 4: 87-93.
53. Nasulewicz A, Mazur A, Opolski A. Role of copper in tumour angiogenesis-clinical implications. J Trace Elem Med Biol 2004; 18: 1-8.
54. Zowczak M, Iskra M, Torlinski L, Cofta S. Analysis of serum copper and zinc concentrations in cancer patients. Biol Trace Elem Res 2001; 82: 1-8.
55. Yoshida D, Ikeda Y, Nakazawa S. Quantitative analysis of copper, zinc and copper/zinc ratio in selected human brain tumors. J Neurooncol 1993; 16: 109-15.
56. Senra Varela A, Lopez Saez JJ, Quintela Senra D. Serum ceruloplasmin as a diagnostic marker of cancer. Cancer Lett 1997; 121: 139-45.
57. Hu GF. Copper stimulates proliferation of human endothelial cells under culture. J Cell Biochem 1998; 69: 326-35.
58. Parke A, Bhattacherjee P, Palmer RM, Lazarus NR. Characterization and quantification of copper sulfate-induced vascularization of the rabbit cornea. Am J Pathol 1988; 130: 173-8.
59. Pan Q, Kleer CG, van Golen KL, Irani J, Bottema KM, Bias C, et al. Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Cancer Res 2002; 62: 4854-9.
60. Ziche M, Jones J, Gullino PM. Role of prostaglandin E1 and copper in angiogenesis. J Natl Cancer Inst 1982; 69: 475-82.
61. Staunton JE, Slonim DK, Coller HA, Tamayo P, Angelo MJ, Park J, et al. Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad Sci USA 2001; 98: 10787-92.
62. Miranda S, Opazo C, Larrondo LF, Munoz FJ, Ruiz F, Leighton F, et al. The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease. Prog Neurobiol 2000; 62: 633-48.
63. Selkoe DJ. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 1998; 8: 447-53.
64. Soto C, Branes MC, Alvarez J, Inestrosa NC. Structural determinants of the Alzheimer's amyloid beta-peptide. J Neurochem 1994; 63: 1191-8.
65. Yankner BA. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 1996; 16: 921-32.
66. Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castano EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nature Med 1998; 4: 822-6.
67. Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, et al. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 1999; 38: 7609-16.
68. Butterfield DA, Hensley K, Cole P, Subramaniam R, Aksenov M, Aksenova M, et al. Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease. J Neurochem 1997; 68: 2451-7.
69. Stadtman ER. Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Free Radic Boil Med 1990; 9: 315-25.
70. Wong PC, Rothstein JD, Price DL. The genetic and molecular mechanisms of motor neuron disease. Curr Opin Neurobiol 1998; 8: 791-9.
71. Multhaup G, Ruppert T, Schlicksupp A, Hesse L, Bill E, Pipkorn R, et al. Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide. Biochemistry 1998; 37: 7224-30.
72. Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 2001; 30: 665-76.
73. Cerpa W, Varela-Nallar L, Reyes AE, Minniti AN, Inestrosa NC. Is there a role for copper in neurodegenerative diseases? Mol Aspects Med 2005; 26: 405-20.
74. Jones CE, Abdelraheim SR, Brown DR, Viles JH. Preferential Cu2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein. J Biol Chem 2004; 279: 32018-27.
75. Sigurdsson EM, Brown DR, Alim MA, Scholtzova H, Carp R, Meeker HC, et al. Copper chelation delays the onset of prion disease. J Biol Chem 2003; 278: 46199-202.
76. Picco SJ, De Luca JC, Mattioli G, Dulout FN. DNA damage induced by copper deficiency in cattle assessed by the Comet assay. Mutat Res 2001; 498: 1-6.
77. Kumar N, Gross JB, Jr, Ahlskog JE. Copper deficiency myelopathy produces a clinical picture like subacute combined degeneration. Neurology 2004; 63: 33-9.
78. Offen D, Gilgun-Sherki Y, Barhum Y, Benhar M, Grinberg L, Reich R, et al. A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis. J Neurochem 2004; 89: 1241-51.
79. Czachor JD, Cherian MG, Koropatnick J. Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone. J Inorg Biochem 2002; 88: 213-22.
80. Cai L, Li XK, Song Y, Cherian MG. Essentiality, toxicology and chelation therapy of zinc and copper. Curr Med Chem 2005; 12: 2753-63.
81. Clarke J. A dictionary of practical materia medica. B. Jain Publishers Pvt. Ltd.; 1990; 1: 633-44.