Comparison of 3 cytotoxicity screening assays and their application to the selection of novel antibacterial hits

Journal of Biomolecular Screening

Volumn 14, Issue 2, 2009, Pages 142-150

  Peternel, Luka ^a   Kotnik, Miha ^a   Preželj, Andrej ^a   Urleb, Uroš ^a  

^a Lek dd   (Slovenia)

Author keywords

Antibacterial hits; ATP; Cytotoxicity screening assay; Safety margins

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ANTIBIOTIC AGENT; CHLORPROMAZINE; CLOZAPINE; DICLOFENAC; MESYLIC ACID METHYL ESTER; PARACETAMOL; RESAZURIN; RIFAMPICIN; TAMOXIFEN; TROGLITAZONE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; CELL ASSAY; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG METABOLISM; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; ENZYME RELEASE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTRACELLULAR SPACE; MAMMAL CELL; MEMBRANE RUPTURE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; STAPHYLOCOCCUS AUREUS; TOXICITY TESTING;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; CYTOTOXINS; DRUG EVALUATION, PRECLINICAL; HUMANS; JURKAT CELLS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MODELS, BIOLOGICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA;

EID: 61849175393     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057108329452     Document Type: Article

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