Clinically relevant concentrations of di (2-ethylhexyl) phthalate (DEHP) uncouple cardiac syncytium

Toxicology and Applied Pharmacology

Volumn 236, Issue 1, 2009, Pages 25-38

  Gillum, Nikki ^a   Karabekian, Zaruhi ^a   Swift, Luther M ^a   Brown, Ronald P ^b   Kay, Matthew W ^a,c   Sarvazyan, Narine ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b CENTER FOR DEVICES AND RADIOLOGICAL HEALTH   (United States)

^c George Washington University   (United States)

Author keywords

Cardiomyocytes; Connexin; Gap junction; Phthalate

Indexed keywords

CONNEXIN 43; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PLASTICIZER; POLYVINYLCHLORIDE; VIMENTIN;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL MOTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; FIBROBLAST; GAP JUNCTION; HEART CONDUCTION; HEART CONTRACTION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; LEACHING; MONOLAYER CULTURE; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RIGIDITY; SYNCYTIUM; TRANSPORT KINETICS; WESTERN BLOTTING;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; CADHERINS; CALCIUM SIGNALING; CELL COMMUNICATION; CELLS, CULTURED; CONNEXIN 43; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GAP JUNCTIONS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PAXILLIN; PLASTICIZERS; PPAR ALPHA; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; VIMENTIN;

ANIMALIA; RATTUS;

EID: 61849148828     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.12.027     Document Type: Article

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