Reduced atrial connexin43 expression after pediatric heart surgery

Biochemical and Biophysical Research Communications

Volumn 342, Issue 1, 2006, Pages 310-315

  Pavlovic, Mladen ^a,b   Schaller, André ^b   Ammann, Roland A ^a   Sanz, Javier ^b   Pfammatter, Jean Pierre ^a   Carrel, Thierry ^a   Berdat, Pascal ^a   Gallati, Sabina ^b  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

Atrium; Cardiopulmonary bypass; Connexin; Pediatric; Volume overload

Indexed keywords

CONNEXIN 40; CONNEXIN 43;

ARTICLE; CARDIOPULMONARY BYPASS; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE EXPRESSION; HEART MUSCLE; HEART RIGHT ATRIUM; HEART SURGERY; HEART VENTRICLE; HUMAN; HUMAN TISSUE; PEDIATRIC SURGERY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION;

ADOLESCENT; CARDIAC SURGICAL PROCEDURES; CHILD; CHILD, PRESCHOOL; CONNEXIN 43; GENE EXPRESSION REGULATION; HEART ATRIA; HEART VENTRICLES; HUMANS; INFANT; MYOCARDIUM; RNA, MESSENGER;

EID: 32644470812     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.146     Document Type: Article

References (31)

1. J.H. Moller, and J.I.E. Hoffman Pediatric Cardiovascular Medicine first ed. 2000 Churchill Livingstone Philadelphia
2. H.A. Huysmans, M. Vrakking, and W.J. van Boven Late follow-up after surgical correction of atrial septal defect of the secundum type Z. Kardiol. 78 1989 43 45
3. U. Wetzel, A. Boldt, J. Lauschke, J. Weigl, P. Schirdewahn, A. Dorszewski, N. Doll, G. Hindricks, S. Dhein, and H. Kottkamp Expression of connexins 40 and 43 in human left atrium in atrial fibrillation of different aetiologies Heart 91 2005 166 170
4. D.E. Gutstein, G.E. Morley, D. Vaidya, F. Liu, F.L. Chen, H. Stuhlmann, and G.I. Fishman Heterogeneous expression of gap junction channels in the heart leads to conduction defects and ventricular dysfunction Circulation 104 2001 1194 1199
5. H. Kitamura, Y. Ohnishi, A. Yoshida, K. Okajima, H. Azumi, A. Ishida, E.J. Galeano, S. Kubo, Y. Hayashi, H. Itoh, and M. Yokoyama Heterogeneous loss of connexin43 protein in nonischemic dilated cardiomyopathy with ventricular tachycardia J. Cardiovasc. Electrophysiol. 13 2002 865 870
6. N.J. Severs, S. Rothery, E. Dupont, S.R. Coppen, H.I. Yeh, Y.S. Ko, T. Matsushita, R. Kaba, and D. Halliday Immunocytochemical analysis of connexin expression in the healthy and diseased cardiovascular system Microsc. Res. Tech. 52 2001 301 322
7. D.D. Spragg, C. Leclercq, M. Loghmani, O.P. Faris, R.S. Tunin, D. DiSilvestre, E.R. McVeigh, G.F. Tomaselli, and D.A. Kass Regional alterations in protein expression in the dyssynchronous failing heart Circulation 108 2003 929 932
8. M.V. Podgoreanu, G.A. Michelotti, Y. Sato, M.P. Smith, S. Lin, R.W. Morris, H.P. Grocott, J.P. Mathew, and D.A. Schwinn Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes J. Thorac. Cardiovasc. Surg. 130 2005 330 339
9. M. Ruel, C. Bianchi, T.A. Khan, S. Xu, J.R. Liddicoat, P. Voisine, E. Araujo, H. Lyon, I.S. Kohane, T.A. Libermann, and F.W. Sellke Gene expression profile after cardiopulmonary bypass and cardioplegic arrest J. Thorac. Cardiovasc. Surg. 126 2003 1521 1530
10. W.M. Breisblatt, K.L. Stein, C.J. Wolfe, W.P. Follansbee, J. Capozzi, J.M. Armitage, and R.L. Hardesty Acute myocardial dysfunction and recovery: a common occurrence after coronary bypass surgery J. Am. Coll. Cardiol. 15 1990 1261 1269
11. J.E. Tamis, and J.S. Steinberg Atrial fibrillation independently prolongs hospital stay after coronary artery bypass surgery Clin. Cardiol. 23 2000 155 159
12. H.I. Yeh, S.H. Hou, H.R. Hu, Y.N. Lee, J.Y. Li, E. Dupont, S.R. Coppen, Y.S. Ko, N.J. Severs, and C.H. Tsai Alteration of gap junctions and connexins in the right atrial appendage during cardiopulmonary bypass J. Thorac. Cardiovasc. Surg. 124 2002 1106 1112
13. N.S. Peters, N.J. Severs, S.M. Rothery, C. Lincoln, M.H. Yacoub, and C.R. Green Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium Circulation 90 1994 713 725
14. M.J.A. Van Kempen, J.L.M. Vermeulen, A.F.M. Moorman, D. Gros, D.L. Paul, and W.H. Lamers Developmental changes of connexin40 and connexin43 mRNA distribution patterns in the rat heart Cardiovasc. Res. 32 1996 886 900
15. B. Delorme, E. Dahl, T. Jarry-Guichard, J.P. Briand, K. Willecke, D. Gros, and M. Theveniau-Ruissy Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system Circ. Res. 81 1997 423 437
16. S.R. Coppen, R.A. Kaba, D. Halliday, E. Dupont, J.N. Skepper, S. Elneil, and N.J. Severs Comparison of connexin expression patterns in the developing mouse heart and human foetal heart Mol. Cell. Biochem. 242 2003 121 127
17. M. Pavlovic, A. Schaller, J.P. Pfammatter, T. Carrel, P. Berdat, and S. Gallati Age-dependent suppression of SERCA2a mRNA in pediatric atrial myocardium Biochem. Biophys. Res. Commun. 326 2005 344 348
18. W. Liu, and D.A. Saint Validation of a quantitative method for real time PCR kinetics Biochem. Biophys. Res. Commun. 294 2002 347 353
19. S.N. Peirson, J.N. Butler, and R.G. Foster Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis Nucleic Acids Res. 31 2003 14 73
20. D.G. Altman Practical Statistics for Medical Research 1991 Chapman & Hall Boca Raton, FL
21. A. Agresti Categorical Data Analysis 2002 Wiley Chichester
22. T. Nao, T. Ohkusa, Y. Hisamatsu, N. Inoue, T. Matsumoto, J. Yamada, A. Shimizu, Y. Yoshiga, T. Yamagata, S. Kobayashi, M. Yano, K. Hamano, and M. Matsuzaki Comparison of expression of connexin in right atrial myocardium in patients with chronic atrial fibrillation versus those in sinus rhythm Am. J. Cardiol. 91 2003 678 683
23. S. Kostin, G. Klein, Z. Szalay, S. Hein, E.P. Bauer, and J. Schaper Structural correlate of atrial fibrillation in human patients Cardiovasc. Res. 54 2002 361 379
24. L. Polontchouk, J.A. Haefliger, B. Ebelt, T. Schaefer, D. Stuhlmann, U. Mehlhorn, F. Kuhn-Regnier, E.R. De Vivie, and S. Dhein Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria J. Am. Coll. Cardiol. 38 2001 883 891
25. E. Dupont, Y. Ko, S. Rothery, S.R. Coppen, M. Baghai, M. Haw, and N.J. Severs The gap-junctional protein, connexin40, is elevated in patients susceptible to post-operative atrial fibrillation Circulation 103 2001 842 849
26. P. Kanagaratnam, S. Rothery, P. Patel, N.J. Severs, and N.S. Peters Relative expression of immunolocalized connexins 40 and 43 correlates with human atrial conduction properties J. Am. Coll. Cardiol. 39 2002 116 123
27. N.S. Peters, C.R. Green, P.A. Poole-Wilson, and N.J. Severs Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischemic human hearts Circulation 88 1993 864 875
28. E. Dupont, T. Matsushita, R.A. Kaba, C. Vozzi, S.R. Coppen, N. Khan, R. Kaprielian, M.H. Yacoub, and N.J. Severs Altered connexin expression in human congestive heart failure J. Mol. Cell. Cardiol. 33 2001 359 371
29. R.R. Kaprielian, M. Gunning, E. Dupont, M.N. Sheppard, S.M. Rothery, R. Underwood, D.J. Pennell, K. Fox, J. Pepper, P.A. Poole-Wilson, and N.J. Severs Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle Circulation 97 1998 651 660
30. L.M. Davis, H.L. Kanter, E.C. Beyer, and J.E. Saffitz Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties J. Am. Coll. Cardiol. 24 1994 1124 1132
31. C. Vozzi, E. Dupont, S.R. Coppen, H.I. Yeh, and N.J. Severs Chamber-related differences in connexin expression in the human heart J. Mol. Cell. Cardiol. 31 1999 991 1003