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Volumn 56, Issue 5, 1997, Pages 311-316

Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that is independent of peroxisome proliferator-activated receptor-α

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DRUG VEHICLE; MESSENGER RNA; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; ZINC;

EID: 0031441443     PISSN: 00403709     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-9926(199711)56:5<311::aid-tera4>3.0.co;2-%23     Document Type: Article
Times cited : (80)

References (31)
  • 1
    • 0023001696 scopus 로고
    • 6-Mercaptopurine-induced alterations in mineral metabolism and teratogenesis in the rat
    • Amemiya, K., C.L. Keen, and L.S. Hurley (1986) 6-Mercaptopurine-induced alterations in mineral metabolism and teratogenesis in the rat. Teratology, 34:321-334.
    • (1986) Teratology , vol.34 , pp. 321-334
    • Amemiya, K.1    Keen, C.L.2    Hurley, L.S.3
  • 4
    • 0019802671 scopus 로고
    • Influence of ashing techniques on the analysis of trace elements in animal tissues
    • Clegg, M.S., C.L. Keen, B. Lonnerdal and L.S. Hurley (1981) Influence of ashing techniques on the analysis of trace elements in animal tissues. Biol. Trace. Element Res., 3:107-115.
    • (1981) Biol. Trace. Element Res. , vol.3 , pp. 107-115
    • Clegg, M.S.1    Keen, C.L.2    Lonnerdal, B.3    Hurley, L.S.4
  • 5
    • 0025945144 scopus 로고
    • The role of metallothionein induction and altered zinc status in maternally mediated developmental toxicity: Comparison of the effects of urethane and styrene in rats
    • Daston, G.P., G.J. Overmann, M.W. Taubeneck, L.D. Lehman-McKeeman, J.M. Rogers and C.L. Keen (1991) The role of metallothionein induction and altered zinc status in maternally mediated developmental toxicity: Comparison of the effects of urethane and styrene in rats. Toxicol. Appl. Pharmacol., 110:450-63.
    • (1991) Toxicol. Appl. Pharmacol. , vol.110 , pp. 450-463
    • Daston, G.P.1    Overmann, G.J.2    Taubeneck, M.W.3    Lehman-McKeeman, L.D.4    Rogers, J.M.5    Keen, C.L.6
  • 7
    • 0020067649 scopus 로고
    • Light and electron microscopy of liver in hyperlipoproteinemic patients under long-term gemfibrozil treatment
    • De La Iglesia, F.A., J.E. Lewis, R.A. Buchanan, E.L. Marcus and G. McMahon (1982) Light and electron microscopy of liver in hyperlipoproteinemic patients under long-term gemfibrozil treatment. Atherosclerosis, 43:19-37.
    • (1982) Atherosclerosis , vol.43 , pp. 19-37
    • De La Iglesia, F.A.1    Lewis, J.E.2    Buchanan, R.A.3    Marcus, E.L.4    McMahon, G.5
  • 8
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • Gottlicher, M., E. Widmark, Q. Li and J.A. Gustafsson (1992) Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl. Acad. Sci. U.S.A., 89:4653-7.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 4653-4657
    • Gottlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.A.4
  • 9
    • 0027525576 scopus 로고
    • The peroxisome proliferator-activated receptor:retinoid x receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
    • Issemann, I., R.A. Prince, J.D. Tugwood and S. Green (1993) The peroxisome proliferator-activated receptor:retinoid x receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrinol., 11:37-47.
    • (1993) J. Mol. Endocrinol. , vol.11 , pp. 37-47
    • Issemann, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 10
    • 85173855487 scopus 로고    scopus 로고
    • Teratogenic effects of essential trace elements: Deficiencies and excesses
    • L.W. Chang, ed. Boca Raton: CRC
    • Keen, C.L. (1996) Teratogenic effects of essential trace elements: Deficiencies and excesses. In: Toxicology of Metals. L.W. Chang, ed. Boca Raton: CRC, pp. 977-1001.
    • (1996) Toxicology of Metals , pp. 977-1001
    • Keen, C.L.1
  • 11
    • 0024573674 scopus 로고
    • The effect of valproic acid on 65Zn distribution in the pregnant rat
    • Keen, C.L., J.M. Peters and L.S. Hurley (1989) The effect of valproic acid on 65Zn distribution in the pregnant rat. J. Nutr., 119:607-11.
    • (1989) J. Nutr. , vol.119 , pp. 607-611
    • Keen, C.L.1    Peters, J.M.2    Hurley, L.S.3
  • 13
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S.S., T. Pineau, J. Drago, E.J. Lee, J.W. Owens, D.L. Kroetz, P.M. Fernandez-Salguero, H. Westphal and F.J. Gonzalez (1995) Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol., 75:3012-22.
    • (1995) Mol. Cell. Biol. , vol.75 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 14
    • 0023841810 scopus 로고
    • Mechanisms of regulation of rat hepatic metallothionein-I and metallothionein-II levels following administration of zinc
    • Lehman-McKeeman, L.D., G.K. Andrews and C.D. Klaassen (1988) Mechanisms of regulation of rat hepatic metallothionein-I and metallothionein-II levels following administration of zinc. Toxicol. Appl. Pharmacol., 92:1-9.
    • (1988) Toxicol. Appl. Pharmacol. , vol.92 , pp. 1-9
    • Lehman-McKeeman, L.D.1    Andrews, G.K.2    Klaassen, C.D.3
  • 15
    • 0026100678 scopus 로고
    • Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium
    • Moody, D.E., J.K. Reddy, B.G. Lake, J.A. Popp and D.H. Reese (1991) Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium. Fundam. Appl. Toxicol., 16:233-48.
    • (1991) Fundam. Appl. Toxicol. , vol.16 , pp. 233-248
    • Moody, D.E.1    Reddy, J.K.2    Lake, B.G.3    Popp, J.A.4    Reese, D.H.5
  • 16
    • 0027738795 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR): Structure, mechanisms of activation and diverse functions
    • Motojima, K. (1993) Peroxisome proliferator-activated receptor (PPAR): Structure, mechanisms of activation and diverse functions. Cell Struct. Funct., 18:267-77.
    • (1993) Cell Struct. Funct. , vol.18 , pp. 267-277
    • Motojima, K.1
  • 17
    • 0020027597 scopus 로고
    • Comparison of metallothionein determination by polarographic and cadmium-saturation methods
    • Onosaka, S. and M.G. Cherian (1982) Comparison of metallothionein determination by polarographic and cadmium-saturation methods. Toxicol. Appl. Pharmacol., 63:270-4.
    • (1982) Toxicol. Appl. Pharmacol. , vol.63 , pp. 270-274
    • Onosaka, S.1    Cherian, M.G.2
  • 18
    • 0020334784 scopus 로고
    • Dimethoxyethyl phthalate: Embryopathy, teratogenicity, fetal metabolism and the role of zinc in the rat
    • Parkhie, M.R., M. Webb and M.A. Norcross (1982) Dimethoxyethyl phthalate: Embryopathy, teratogenicity, fetal metabolism and the role of zinc in the rat. Environ. Health Perspect., 45:89-97.
    • (1982) Environ. Health Perspect. , vol.45 , pp. 89-97
    • Parkhie, M.R.1    Webb, M.2    Norcross, M.A.3
  • 19
    • 0030001343 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate
    • Peters, J.M., Y.C. Zhou, P.A. Ram, S.S. Lee, F.J. Gonzalez and D.J. Waxman (1996) Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate. Mol. Pharmacol., 50:67-74.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 67-74
    • Peters, J.M.1    Zhou, Y.C.2    Ram, P.A.3    Lee, S.S.4    Gonzalez, F.J.5    Waxman, D.J.6
  • 20
    • 85080532538 scopus 로고    scopus 로고
    • Role of PPAR-alpha in the mechanism of action of the non-genotoxic carcinogen and peroxisome proliferator Wy-14,643
    • in press
    • Peters, J.M., R.C. Cattley and F.J. Gonzalez (1997) Role of PPAR-alpha in the mechanism of action of the non-genotoxic carcinogen and peroxisome proliferator Wy-14,643. Cancer. Res., in press.
    • (1997) Cancer. Res.
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 21
    • 0026531580 scopus 로고
    • Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver
    • Rao, M.S., S. Musunuri and J.K. Reddy (1992) Dehydroepiandrosterone-induced peroxisome proliferation in the rat liver. Pathobiology, 60:82-6.
    • (1992) Pathobiology , vol.60 , pp. 82-86
    • Rao, M.S.1    Musunuri, S.2    Reddy, J.K.3
  • 22
    • 0030783119 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require PPARα
    • Ren, B., A.P. Thelen, J.M. Peters, F.J. Gonzalez and D.B. Jump (1997) Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require PPARα. J. Biol. Chem., 272:26827-26832.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26827-26832
    • Ren, B.1    Thelen, A.P.2    Peters, J.M.3    Gonzalez, F.J.4    Jump, D.B.5
  • 23
    • 0021916047 scopus 로고
    • Assessment of the teratogenicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in mice
    • Shiota, K. and S. Mima (1985) Assessment of the teratogenicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in mice. Arch. Toxicol., 56:263-6.
    • (1985) Arch. Toxicol. , vol.56 , pp. 263-266
    • Shiota, K.1    Mima, S.2
  • 24
    • 0020334781 scopus 로고
    • Teratogenicity of di(2-ethylhexyl)phthyalate (DEHP) and di-n-butyl phthalate (DBP) in mice
    • Shiota, K. and H. Nishimura (1982) Teratogenicity of di(2-ethylhexyl)phthyalate (DEHP) and di-n-butyl phthalate (DBP) in mice. Environ. Health Perspect., 45:65-70.
    • (1982) Environ. Health Perspect. , vol.45 , pp. 65-70
    • Shiota, K.1    Nishimura, H.2
  • 25
    • 0015260649 scopus 로고
    • Teratogenicity of phthalate esters in rats
    • Singh, A.R., W.H. Lawrence and J. Autian (1972) Teratogenicity of phthalate esters in rats. J. Pharm. Sci., 61:51-5.
    • (1972) J. Pharm. Sci. , vol.61 , pp. 51-55
    • Singh, A.R.1    Lawrence, W.H.2    Autian, J.3
  • 26
    • 0028139848 scopus 로고
    • Altered maternal zinc metabolism following exposure to diverse developmental toxicants
    • Taubeneck, M.W., G.P. Daston, J.M. Rogers and C.L. Keen (1994) Altered maternal zinc metabolism following exposure to diverse developmental toxicants. Reprod. Toxicol., 8:25-40.
    • (1994) Reprod. Toxicol. , vol.8 , pp. 25-40
    • Taubeneck, M.W.1    Daston, G.P.2    Rogers, J.M.3    Keen, C.L.4
  • 27
    • 0028987451 scopus 로고
    • Tumor necrosis factor-alpha alters maternal and embryonic zinc metabolism and is developmentally toxic in mice
    • Taubeneck, M.W., G.P. Daston, J.M. Rogers, M.E. Gershwin, A. Ansari and C.L. Keen (1995) Tumor necrosis factor-alpha alters maternal and embryonic zinc metabolism and is developmentally toxic in mice. J. Nutr., 125:908-919.
    • (1995) J. Nutr. , vol.125 , pp. 908-919
    • Taubeneck, M.W.1    Daston, G.P.2    Rogers, J.M.3    Gershwin, M.E.4    Ansari, A.5    Keen, C.L.6
  • 29
    • 0023932939 scopus 로고
    • Developmental toxicity evaluation of dietary di(2-ethylhexyl)phthalate in Fischer 344 rats and CD-1 mice
    • Tyl, R.W., C.J. Price, M.C. Marr and C.A. Kimmel (1988) Developmental toxicity evaluation of dietary di(2-ethylhexyl)phthalate in Fischer 344 rats and CD-1 mice. Fundam. Appl. Toxicol., 10:395-412.
    • (1988) Fundam. Appl. Toxicol. , vol.10 , pp. 395-412
    • Tyl, R.W.1    Price, C.J.2    Marr, M.C.3    Kimmel, C.A.4
  • 30
    • 0024460685 scopus 로고
    • Induction of hepatic metallothionein in male B6C3F1 mice exposed to hepatic tumor promoters: Effects of phenobarbital, acetaminophen, sodium barbital and di(2-ethylhexyl) phthalate
    • Waalkes, M.P. and J.M. Ward (1989) Induction of hepatic metallothionein in male B6C3F1 mice exposed to hepatic tumor promoters: Effects of phenobarbital, acetaminophen, sodium barbital and di(2-ethylhexyl) phthalate. Toxicol. Appl. Pharmacol., 100:217-226.
    • (1989) Toxicol. Appl. Pharmacol. , vol.100 , pp. 217-226
    • Waalkes, M.P.1    Ward, J.M.2
  • 31
    • 85080541270 scopus 로고    scopus 로고
    • Receptor and non-receptor mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor α-null mice
    • in press
    • Ward, J.M., J.M. Peters, C.M. Perella and F.J. Gonzalez (1997) Receptor and non-receptor mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor α-null mice. Toxicol. Pathol., in press.
    • (1997) Toxicol. Pathol.
    • Ward, J.M.1    Peters, J.M.2    Perella, C.M.3    Gonzalez, F.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.