Follow-up study of adolescents exposed to Di(2-ethylhexyl) phthalate (DEHP) as neonates on extracorporeal membrane oxygenation (ECMO) support

Environmental Health Perspectives

Volumn 112, Issue 13, 2004, Pages 1339-1340

  Rais Bahrami, Khodayar ^a   Nunez, Susan ^a   Revenis, Mary E ^a   Luban, Naomi L C ^a   Short, Billie L ^a  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

DEHP; ECMO; Toxicity

Indexed keywords

ESTRADIOL; FOLLITROPIN; LUTEINIZING HORMONE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; TESTOSTERONE;

ADOLESCENT; AGE DISTRIBUTION; ARTICLE; BODY HEIGHT; BODY WEIGHT; CHILD DEVELOPMENT; CLINICAL ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EXTRACORPOREAL OXYGENATION; FEMALE; FOLLOW UP; HEAD CIRCUMFERENCE; HUMAN; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; MALE; MARFAN SYNDROME; PENIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PUBERTY; SEX RATIO; SEXUAL MATURITY; SURVIVAL; TESTIS SIZE; THYROID FUNCTION TEST; TOXICITY; TUBE;

ADOLESCENT; CHILD DEVELOPMENT; DIETHYLHEXYL PHTHALATE; DURABLE MEDICAL EQUIPMENT; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; FOLLOW-UP STUDIES; GONADS; HUMANS; INFANT, NEWBORN; MALE; PUBERTY;

ANIMALIA;

EID: 4644229324     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.6901     Document Type: Article

References (22)

1. Crocker J, Safe S, Acott P. 1988. Effects of chronic phthalate exposure on the kidney. J Toxicol Environ Health 23:433-444.
2. Davis BJ, Maronpot RR, Heindel JJ. 1994. Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats. Toxicol Appl Pharmacol 128:216-223.
3. Doull J, Cattley R, Elcombe C, Lake BG, Swenberg J, Wilkinson C, et al. 1999. A cancer risk assessment of di(2-ethylhexyl)-phthalate: application of the new U.S. EPA risk assessment guidelines. Regul Toxicol Pharmacol 29(3):327-357.
4. Foster PM, Mylchreest E, Gaido KW, Sar M. 2001. Effects of phthalate esters on the developing reproductive tract of male rats. Hum Reprod Update 7:231-235.
5. Huber WW, Grasl-Kraupp B, Schulte-Hermann R. 1996. Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk. Crit Rev Toxicol 26:365-381.
6. Karle VA, Short BL, Martin GR, Bulas DI, Gaston PR, Luban NCL, et al. 1997. Extrcorporeal membrane oxygenation exposes infants to the plasticizer, DEHP. Crit Care Med 25:696-703.
7. Kevy S, Jacobson M. 1982. Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl-chloride) blood bags following transfusion. Environ Health Perspect 45:57-64.
8. Latini G. 2000. Potential hazards of exposure to di-(2-ethylhexyl)-phthalate in babies. A review. Biol Neonate 78:269-276.
9. Lewandowski M, Fernandes J, Chen TS. 1980. Assessment of the teratogenic potential of plasma-soluble extracts of diethylhexyl phthalate plasticized polyvinyl chloride plastics in rats. Toxicol Appl Pharmacol 54:141-147.
10. Lovekamp-Swan T, Davis BJ. 2003. Mechanisms of phthalate ester toxicity in the female reproductive system. Environ Health Perspect 111:139-146.
11. Morris MN, Udry JR. 1980. Validation of a self-administered instrument to assess stage of adolescent development. J Youth Adolesc 9:271-280.
12. Park JD, Habeebu SS, Klaassen CD. 2002. Testicular toxicity of di-(2-ethylhexyl)phthalate in young Sprague-Dawley rats. Toxicology 171:105-115.
13. Parks LG, Ostby JS, Lambright CR, Abbott BD, Klinefelter GR, Barlow NJ, et al. 2000. The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci 58:339-349.
14. Poon R, Lecavaliert P, Mueller R, Valli VE, Procter BG, Chu I. 1997. Subchronic oral toxicity of di-n-octyl phthalate and di(2-ethylhexyl) phthalate in the rat. Food Chem Toxicol 35:225-239.
15. Rock G, Lebow RS, Franklin C, Burnett R, Tocchi M. 1987. Hypotension and cardiac arrest in rats after infusion of mono (2-ethylhexyl) phthalate (MEHP) a contaminant of stored blood. N Engl J Mad 316:1218-1219.
16. Roth B, Herkenrath P, Lehmann HJ, Ohles HD, Homig HJ, Benz-Bohm G, et al. 1988. Di-(2-ethylhexyl)-phthalate as plasticizer in PVC respiratory tubing systems: indications of hazardous effects on pulmonary function in mechanically ventilated, preterm infants. Eur J Pediatr 147:41-46.
17. Rubin RJ, Schiffer CA. 1976, Fate in humans of the plasticizer, di-2-ethylhexyl phthalate, arising from transfusion of platelets stored in vinyl plastic bags. Transfusion 16:330-335.
18. Shneider B, Schena J, Truog R, Jacobson M, Kevy S. 1989. Exposure to di (2-ethylhexyl) phthalate in infants receiving extracorporeal membrane oxygenation. N Engl J Med 320:1563.
19. Tanner JM. 1975. Growth and endocrinology of the adolescent. In: Endocrine and Disease of Childhood (Gardner LJ II, ed). Philadelphia:W.B. Saunders, 14-64.
20. Thomas JA, Schein LG, Gupta PK, McCafferty RE, Felice PR, Donovan MP. 1979. Failure of monoethylhexyl phthalate to cause teratogenic effects in offspring of rabbits. Toxicol Appl Pharmacol 51:523-528.
21. Tickner JA, Schettler T, Guidotti T, McCally M, Rossi M. 2001. Health risks posed by use of di-2-ethylhexyl phthalate (DEHP) in PVC medical devices: a critical review. Am J Ind Med 39:100-111.
22. Ward JM, Peters JM, Perella CM, Gonzalez FJ. 1998. Receptor and nonreceptor mediated organ-specific toxicity of DEHP in peroxisome proliferator-activated receptor alpha-null mice. Toxicol Pathol 26:240-246.