-
1
-
-
0026324283
-
Measurement of steroid hydroxylation by high performance liquid chromatography as indicator of P450 identity and function
-
Arlotto MP, Trant JM, Estabook RW. 1991. Measurement of steroid hydroxylation by high performance liquid chromatography as indicator of P450 identity and function. Methods in Enzymology 206:454-462.
-
(1991)
Methods in Enzymology
, vol.206
, pp. 454-462
-
-
Arlotto, M.P.1
Trant, J.M.2
Estabook, R.W.3
-
2
-
-
0028106482
-
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver
-
Burke MD, Thompson S, Weaver RJ, Wolf CR, Mayer RT. 1994. Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochemical Pharmacology 48:923-936.
-
(1994)
Biochemical Pharmacology
, vol.48
, pp. 923-936
-
-
Burke, M.D.1
Thompson, S.2
Weaver, R.J.3
Wolf, C.R.4
Mayer, R.T.5
-
3
-
-
31344437157
-
Quantification of the expression and inducibility of 12 rat cytochromes P450 isoforms by quantitative RT-PCR
-
Caron E, Rioux N, Nicolas O, Lebel-Talbot H, Hamelin BA. 2005. Quantification of the expression and inducibility of 12 rat cytochromes P450 isoforms by quantitative RT-PCR. Journal of Biochemical and Molecular Toxicology 19:368-378.
-
(2005)
Journal of Biochemical and Molecular Toxicology
, vol.19
, pp. 368-378
-
-
Caron, E.1
Rioux, N.2
Nicolas, O.3
Lebel-Talbot, H.4
Hamelin, B.A.5
-
4
-
-
0031840976
-
Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with TESTO metabolic patterns
-
Chung WG, Roh HK, Kim HR, Cha YN. 1998. Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with TESTO metabolic patterns. Chemical-Biological Interactions 113:1-14.
-
(1998)
Chemical-Biological Interactions
, vol.113
, pp. 1-14
-
-
Chung, W.G.1
Roh, H.K.2
Kim, H.R.3
Cha, Y.N.4
-
5
-
-
0034903590
-
Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: Description of specific patterns
-
Debersac P, Heidel JM, Amoit MJ, Goudonnet H, Artur Y, Suschetet M, Siess MH. 2001. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food and Chemical Toxicology 39:907-918.
-
(2001)
Food and Chemical Toxicology
, vol.39
, pp. 907-918
-
-
Debersac, P.1
Heidel, J.M.2
Amoit, M.J.3
Goudonnet, H.4
Artur, Y.5
Suschetet, M.6
Siess, M.H.7
-
6
-
-
0032832513
-
Cytochrome P450 isoenzyme specific dealkyltion of alkoxyresorufins in rat brain microsomes
-
Dhawan A, Parmar D, Dayal M, Seth PK. 1999. Cytochrome P450 isoenzyme specific dealkyltion of alkoxyresorufins in rat brain microsomes. Molecular and Cellular Biochemistry 200:169-176.
-
(1999)
Molecular and Cellular Biochemistry
, vol.200
, pp. 169-176
-
-
Dhawan, A.1
Parmar, D.2
Dayal, M.3
Seth, P.K.4
-
7
-
-
0036093847
-
The mucosa of the small intestine: How clinically relevant as an organ of drug metabolism?
-
Doherty MM, Charmann WN. 2002. The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism? Clinical Pharmacokinetics 41:235-253.
-
(2002)
Clinical Pharmacokinetics
, vol.41
, pp. 235-253
-
-
Doherty, M.M.1
Charmann, W.N.2
-
10
-
-
0033001766
-
Inhibition by retinoids of benzo(-)pyrene metabolism catalysed by 3-methylcholanthrene- induced rat cytochrome P450 1A1
-
Huang DY, Ohnishi T, Jiang H, Furukawa A, Ichikawa Y. 1999. Inhibition by retinoids of benzo(-)pyrene metabolism catalysed by 3-methylcholanthrene- induced rat cytochrome P450 1A1. Metabolism 48:689-692.
-
(1999)
Metabolism
, vol.48
, pp. 689-692
-
-
Huang, D.Y.1
Ohnishi, T.2
Jiang, H.3
Furukawa, A.4
Ichikawa, Y.5
-
11
-
-
0032053474
-
A specific hydroxysteroid UGT is responsible for the conjugation of aliphatic alcohols in rat: An estimation of the importance of glucuronidation versus oxidation
-
Iwersen S, Schmoldt A. 1997. A specific hydroxysteroid UGT is responsible for the conjugation of aliphatic alcohols in rat: an estimation of the importance of glucuronidation versus oxidation. Alcohol 15:185-192.
-
(1997)
Alcohol
, vol.15
, pp. 185-192
-
-
Iwersen, S.1
Schmoldt, A.2
-
13
-
-
0036497073
-
Substrate specificity for rat cytochrome P450 (CYP) isoforms: Screening with cDNA-expressed systems of the rat
-
Kobayashi K, Urashima K, Shimada N, Chiba K. 2002. Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat. Biochemical Pharmacology 63:889-896.
-
(2002)
Biochemical Pharmacology
, vol.63
, pp. 889-896
-
-
Kobayashi, K.1
Urashima, K.2
Shimada, N.3
Chiba, K.4
-
15
-
-
0037275568
-
Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine, comparison to the liver
-
Lindell M, Lang M, Lennernäs H. 2003. Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine, comparison to the liver. European Journal of Drug Metabolism and Pharmacokinetics 28:41-48.
-
(2003)
European Journal of Drug Metabolism and Pharmacokinetics
, vol.28
, pp. 41-48
-
-
Lindell, M.1
Lang, M.2
Lennernäs, H.3
-
16
-
-
33747833384
-
Comparison of intrinsic clearance in liver microsomes and hepatocytes from rat and humans: Evaluation of free fraction and uptake in hepatocytes
-
Lu C, Li P, Gallegos R, Uttamsingh V, Xia CQ, Miw GT, Balani SK, Gan LS. 2006. Comparison of intrinsic clearance in liver microsomes and hepatocytes from rat and humans: evaluation of free fraction and uptake in hepatocytes. Drug Metabolism and Disposition 34:1600-1605.
-
(2006)
Drug Metabolism and Disposition
, vol.34
, pp. 1600-1605
-
-
Lu, C.1
Li, P.2
Gallegos, R.3
Uttamsingh, V.4
Xia, C.Q.5
Miw, G.T.6
Balani, S.K.7
Gan, L.S.8
-
17
-
-
0017168412
-
Quantitative determination of cytochrome P450 in rat liver homogenates
-
Matsubara T, Koike M, Touchi A, Tochino Y, Sugeno K. 1976. Quantitative determination of cytochrome P450 in rat liver homogenates. Analytical Biochemistry 75:596-603.
-
(1976)
Analytical Biochemistry
, vol.75
, pp. 596-603
-
-
Matsubara, T.1
Koike, M.2
Touchi, A.3
Tochino, Y.4
Sugeno, K.5
-
18
-
-
44149117977
-
Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats
-
Mitschke D, Reichel A, Fricker G, Moenning U. 2008. Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats. Drug Metabolism and Disposition 36:1039-1045.
-
(2008)
Drug Metabolism and Disposition
, vol.36
, pp. 1039-1045
-
-
Mitschke, D.1
Reichel, A.2
Fricker, G.3
Moenning, U.4
-
19
-
-
0034812580
-
Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures
-
Mohri K, Uesawa Y. 2001. Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures. Pharmaceutical Research 18:1232-1236.
-
(2001)
Pharmaceutical Research
, vol.18
, pp. 1232-1236
-
-
Mohri, K.1
Uesawa, Y.2
-
20
-
-
0027104748
-
Metabolite intermediate complexation of microsomal cytochrome P450 2C11 in male rat liver by nortriptyline
-
Murray M. 1992. Metabolite intermediate complexation of microsomal cytochrome P450 2C11 in male rat liver by nortriptyline. Molecular Pharmacology 42:931-938.
-
(1992)
Molecular Pharmacology
, vol.42
, pp. 931-938
-
-
Murray, M.1
-
21
-
-
78651165715
-
The carbon monoxyde-binding pigment of liver microsomes
-
Omura T, Sato R. 1964. The carbon monoxyde-binding pigment of liver microsomes. Journal of Biological Chemistry 239:2370-2378.
-
(1964)
Journal of Biological Chemistry
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
22
-
-
0029738490
-
First-pass metabolism of MDZ by the human intestine
-
Paine MF, Shen DD, Kunze KL, Perkins JD, Marsh CL, McVicar JP, Barr DM, Gillies BS, Thummel KE. 1996. First-pass metabolism of MDZ by the human intestine. Clinical Pharmacology and Therapeutics 60:14-24.
-
(1996)
Clinical Pharmacology and Therapeutics
, vol.60
, pp. 14-24
-
-
Paine, M.F.1
Shen, D.D.2
Kunze, K.L.3
Perkins, J.D.4
Marsh, C.L.5
McVicar, J.P.6
Barr, D.M.7
Gillies, B.S.8
Thummel, K.E.9
-
23
-
-
4143125870
-
Strain differences in diazepam metabolism at its three metabolic sites in Sprague-Dawley, Brown Norway, Dark Agouti and Wistar strain rats
-
Saito K, Sakai N, Kim HS, Ishizuka M, Kazusaka A, Fujita S. 2004. Strain differences in diazepam metabolism at its three metabolic sites in Sprague-Dawley, Brown Norway, Dark Agouti and Wistar strain rats. Drug Metabolism and Disposition 32:959-965.
-
(2004)
Drug Metabolism and Disposition
, vol.32
, pp. 959-965
-
-
Saito, K.1
Sakai, N.2
Kim, H.S.3
Ishizuka, M.4
Kazusaka, A.5
Fujita, S.6
-
24
-
-
0025294782
-
Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man
-
Sesardic D, Boobis AR, Muray BP, Murray S, Segura J, De le Torre R, Davies DS. 1990. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. British Journal of Clinical Pharmacology 29:651-663.
-
(1990)
British Journal of Clinical Pharmacology
, vol.29
, pp. 651-663
-
-
Sesardic, D.1
Boobis, A.R.2
Muray, B.P.3
Murray, S.4
Segura, J.5
De le Torre, R.6
Davies, D.S.7
-
25
-
-
0033954275
-
Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats
-
Spatzenegger M, Horsmans Y, Verbeeck RK. 2000. Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats. Pharmacology and Toxicology 86:71-77.
-
(2000)
Pharmacology and Toxicology
, vol.86
, pp. 71-77
-
-
Spatzenegger, M.1
Horsmans, Y.2
Verbeeck, R.K.3
-
26
-
-
0037232758
-
Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransfrases involved in drug metabolism in rat everted sacs and intestinal microsomes
-
Takemoto K, Yamazaki H, Tanaka Y, Nanakajima M, Yokoi T. 2003. Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransfrases involved in drug metabolism in rat everted sacs and intestinal microsomes. Xenobiotica 33:43-55.
-
(2003)
Xenobiotica
, vol.33
, pp. 43-55
-
-
Takemoto, K.1
Yamazaki, H.2
Tanaka, Y.3
Nanakajima, M.4
Yokoi, T.5
-
27
-
-
27544446645
-
Characterisation of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies
-
Van de Kerkhoff E, De Graaf I, De Jager M, Meijer D, Groothuis G. 2005. Characterisation of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies. Drug Metabolism and Disposition 33:1613-1620.
-
(2005)
Drug Metabolism and Disposition
, vol.33
, pp. 1613-1620
-
-
Van de Kerkhoff, E.1
De Graaf, I.2
De Jager, M.3
Meijer, D.4
Groothuis, G.5
-
29
-
-
0028226507
-
A comparative study of constitutive and induced alkoxyresorufine O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes
-
Weaver RJ, Thompson S, Smith G, Dickins M, Elcombe CR, Mayer RT, Burke MD. 1994. A comparative study of constitutive and induced alkoxyresorufine O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. Biochemical Pharmacology 47:763-773.
-
(1994)
Biochemical Pharmacology
, vol.47
, pp. 763-773
-
-
Weaver, R.J.1
Thompson, S.2
Smith, G.3
Dickins, M.4
Elcombe, C.R.5
Mayer, R.T.6
Burke, M.D.7
-
30
-
-
0030960145
-
CYP2J subfamily cytochrome P450s in the gastrointestinal tract: Expression, localization and potential functional significance
-
Zelding DC, Foley J, Goldsworthy SM, Cook ME, Boyle JE, Ma J, Moomaw CR, Tomer KB, Steenbergen C, Wu S. 1997. CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization and potential functional significance. Molecular Pharmacology 51:931-943.
-
(1997)
Molecular Pharmacology
, vol.51
, pp. 931-943
-
-
Zelding, D.C.1
Foley, J.2
Goldsworthy, S.M.3
Cook, M.E.4
Boyle, J.E.5
Ma, J.6
Moomaw, C.R.7
Tomer, K.B.8
Steenbergen, C.9
Wu, S.10
-
31
-
-
0032845242
-
Induction of rat intestinal cytochrome P450 2J4
-
Zhang QY, Ding X, Dunbar D, Cao L, Kaminsky LS. 1999. Induction of rat intestinal cytochrome P450 2J4. Drug Metabolism and Disposition 27:1123-1127.
-
(1999)
Drug Metabolism and Disposition
, vol.27
, pp. 1123-1127
-
-
Zhang, Q.Y.1
Ding, X.2
Dunbar, D.3
Cao, L.4
Kaminsky, L.S.5
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