메뉴 건너뛰기




Volumn 74, Issue SUPPL. 111, 2008, Pages

Optimizing the management of renal anemia: Challenges and new opportunities

Author keywords

Anemia; Chronic kidney disease; Continuous erythropoiesis receptor activator; Erythropoiesis stimulating agents; Erythropoietin; Hematide

Indexed keywords

ABSEAMED; BINOCRIT; CNTO 530; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; EPOETIN OMEGA; EPOETIN ZETA; ERYTHROPOIETIN; HEMOGLOBIN; HX 575; HYBRID PROTEIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN; RETACRIT; SILAPO; UNCLASSIFIED DRUG; ANTIANEMIC AGENT; MACROGOL DERIVATIVE; PEPTIDE; RECOMBINANT PROTEIN;

EID: 61549126333     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.525     Document Type: Conference Paper
Times cited : (9)

References (49)
  • 1
    • 5444255241 scopus 로고    scopus 로고
    • The prevalence of anaemia in patients with chronic kidney disease
    • Mcclellan WM, Aronoff SL, Bolton WK. The prevalence of anaemia in patients with chronic kidney disease. Curr Med Res Opin 2004; 20: 1501-1510.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1501-1510
    • Mcclellan, W.M.1    Aronoff, S.L.2    Bolton, W.K.3
  • 2
    • 9144264827 scopus 로고    scopus 로고
    • Anaemia in haemodialysis patients of five European countries: Association with morbidity and mortality in the Dialysis Outcomes and Practice Patterns Study DOPPS)
    • Locatelli F, Pisoni RL, Combe C et al. Anaemia in haemodialysis patients of five European countries: association with morbidity and mortality in the Dialysis Outcomes and Practice Patterns Study DOPPS). Nephrol Dial Transplant 2004; 19: 121-132.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 121-132
    • Locatelli, F.1    Pisoni, R.L.2    Combe, C.3
  • 3
    • 0242611254 scopus 로고
    • Cloning and expression of the human erythropoietin gene
    • Lin FK, Suggs S, Lin CH et al. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci USA 1985; 82: 7580-7584.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7580-7584
    • Lin, F.K.1    Suggs, S.2    Lin, C.H.3
  • 4
    • 0022980521 scopus 로고
    • Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintained by chronic haemodialysis
    • Winearls CG, Oliver DO, Pippard MJ et al. Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintained by chronic haemodialysis. Lancet 1986; 2: 1175-1178.
    • (1986) Lancet , vol.2 , pp. 1175-1178
    • Winearls, C.G.1    Oliver, D.O.2    Pippard, M.J.3
  • 5
    • 0023120533 scopus 로고
    • Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial
    • Eschbach JW, Egrie JC, Downing MR et al. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med 1987; 316: 73-78.
    • (1987) N Engl J Med , vol.316 , pp. 73-78
    • Eschbach, J.W.1    Egrie, J.C.2    Downing, M.R.3
  • 6
    • 0031972657 scopus 로고    scopus 로고
    • Epoetin alfa and beta differ in their erythropoietin isoform compositions and biological properties
    • Storring PL, Tiplady RJ, Gaines Das RE et al. Epoetin alfa and beta differ in their erythropoietin isoform compositions and biological properties. Br J Haematol 1998; 100: 79-89.
    • (1998) Br J Haematol , vol.100 , pp. 79-89
    • Storring, P.L.1    Tiplady, R.J.2    Gaines Das, R.E.3
  • 7
    • 0011364893 scopus 로고
    • Human erythropoietin gene: High level expression in stably transfected mammalian cells and chromosome localization
    • Powell JS, Berkner KL, Lebo RV et al. Human erythropoietin gene: high level expression in stably transfected mammalian cells and chromosome localization. Proc Natl Acad Sci USA 1986; 83: 6465-6469.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6465-6469
    • Powell, J.S.1    Berkner, K.L.2    Lebo, R.V.3
  • 8
    • 0027394760 scopus 로고
    • Structures of sialylated oligosaccharides of human erythropoietin expressed in recombinant BHK-21 cells
    • Nimtz M, Martin W, Wray V et al. Structures of sialylated oligosaccharides of human erythropoietin expressed in recombinant BHK-21 cells. Eur J Biochem 1993; 213: 39-56.
    • (1993) Eur J Biochem , vol.213 , pp. 39-56
    • Nimtz, M.1    Martin, W.2    Wray, V.3
  • 9
    • 1542512110 scopus 로고    scopus 로고
    • Differentiating factors between erythropoiesis- stimulating agents: A guide to selection for anaemia of chronic kidney disease
    • Deicher R, Horl WH. Differentiating factors between erythropoiesis- stimulating agents: a guide to selection for anaemia of chronic kidney disease. Drugs 2004; 64: 499-509.
    • (2004) Drugs , vol.64 , pp. 499-509
    • Deicher, R.1    Horl, W.H.2
  • 10
    • 33847386390 scopus 로고    scopus 로고
    • The Epoetin Delta Study Group. Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients
    • Kwan JT, Pratt RD, The Epoetin Delta Study Group. Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients. Curr Med Res Opin 2007; 23: 307-311.
    • (2007) Curr Med Res Opin , vol.23 , pp. 307-311
    • Kwan, J.T.1    Pratt, R.D.2
  • 11
    • 33748685217 scopus 로고    scopus 로고
    • Comparative testing and pharmacovigilance of biosimilars
    • Locatelli F, Roger S. Comparative testing and pharmacovigilance of biosimilars. Nephrol Dial Transplant 2006; 21(Suppl 5): v13-v16.
    • (2006) Nephrol Dial Transplant , vol.21 , Issue.SUPPL. 5
    • Locatelli, F.1    Roger, S.2
  • 12
    • 0034949634 scopus 로고    scopus 로고
    • Development and characterisation of novel erythropoiesis stimulating protein (NESP)
    • Egrie JC, Browne KJ. Development and characterisation of novel erythropoiesis stimulating protein (NESP). Nephrol Dial Transplant 2001; 16(Suppl 3): 3-13.
    • (2001) Nephrol Dial Transplant , vol.16 , Issue.SUPPL. 3 , pp. 3-13
    • Egrie, J.C.1    Browne, K.J.2
  • 13
    • 0034919301 scopus 로고    scopus 로고
    • European/Australian NESP 980202 Study Group. Novel erythropoiesis stimulating protein for treatment of anemia in chronic renal insufficiency
    • Locatelli F, Olivares J, Walker R et al. European/Australian NESP 980202 Study Group. Novel erythropoiesis stimulating protein for treatment of anemia in chronic renal insufficiency. Kidney Int 2001; 60: 741-747.
    • (2001) Kidney Int , vol.60 , pp. 741-747
    • Locatelli, F.1    Olivares, J.2    Walker, R.3
  • 14
    • 0037317083 scopus 로고    scopus 로고
    • Treatment of anaemia in dialysis patients with unit dosing of darbepoetin alfa at a reduced dose frequency relative to recombinant human erythropoietin (rHuEpo)
    • Locatelli F, Canaud B, Giacardy F et al. Treatment of anaemia in dialysis patients with unit dosing of darbepoetin alfa at a reduced dose frequency relative to recombinant human erythropoietin (rHuEpo). Nephrol Dial Transplant 2003; 18: 362-369.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 362-369
    • Locatelli, F.1    Canaud, B.2    Giacardy, F.3
  • 15
    • 0036436322 scopus 로고    scopus 로고
    • European/Australian NESP 970200 Study Group. Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients
    • Vanrenterghem Y, Barany P, Mann JF et al. European/Australian NESP 970200 Study Group. Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients. Kidney Int 2002; 62: 2167-2175.
    • (2002) Kidney Int , vol.62 , pp. 2167-2175
    • Vanrenterghem, Y.1    Barany, P.2    Mann, J.F.3
  • 16
    • 33947241998 scopus 로고    scopus 로고
    • Darbepoetin alfa once every 2 weeks for treatment of anemia in dialysis patients: A combined analysis of eight multicenter trials
    • Mann J, Kessler M, Villa G et al. Darbepoetin alfa once every 2 weeks for treatment of anemia in dialysis patients: a combined analysis of eight multicenter trials. Clin Nephrol 2007; 67: 140-148.
    • (2007) Clin Nephrol , vol.67 , pp. 140-148
    • Mann, J.1    Kessler, M.2    Villa, G.3
  • 17
    • 33646181084 scopus 로고    scopus 로고
    • Clinical implications of converting stable haemodialysis patients from subcutaneous to intravenous administration of darbepoetin alfa
    • Aarup M, Bryndum J, Dieperink H et al. Clinical implications of converting stable haemodialysis patients from subcutaneous to intravenous administration of darbepoetin alfa. Nephrol Dial Transplant 2006; 21: 1312-1316.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1312-1316
    • Aarup, M.1    Bryndum, J.2    Dieperink, H.3
  • 18
    • 57049186287 scopus 로고    scopus 로고
    • Brandt M, Lazendörfer M, Frische J et al. Different receptor binding activity of C.E.R.A. (continuous erythropoietin receptor activator) compared with epoetin beta determined by surface plasmon resonance and competition assay on UT-7 cells. Nephrol Dial Transplant 2006; 21(Suppl 4): iv9 (Abstract SO018).
    • Brandt M, Lazendörfer M, Frische J et al. Different receptor binding activity of C.E.R.A. (continuous erythropoietin receptor activator) compared with epoetin beta determined by surface plasmon resonance and competition assay on UT-7 cells. Nephrol Dial Transplant 2006; 21(Suppl 4): iv9 (Abstract SO018).
  • 19
    • 34249040576 scopus 로고    scopus 로고
    • Locatelli F, Villa G, De Francisco ALM et al. Effect of a continuous erythropoietin receptor activator (C.E.R.A.) on stable haemoglobin in patients with CKD on dialysis. Curr Med Res Opin 2007; 23: 969-979.
    • Locatelli F, Villa G, De Francisco ALM et al. Effect of a continuous erythropoietin receptor activator (C.E.R.A.) on stable haemoglobin in patients with CKD on dialysis. Curr Med Res Opin 2007; 23: 969-979.
  • 20
    • 35348839061 scopus 로고    scopus 로고
    • MAXIMA study investigators: Intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: a randomised non-inferiority trial (MAXIMA)
    • Levin NW, Fishbane S, Cañedo FV et al. MAXIMA study investigators: intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: a randomised non-inferiority trial (MAXIMA). Lancet 2007; 370: 1415-1421.
    • (2007) Lancet , vol.370 , pp. 1415-1421
    • Levin, N.W.1    Fishbane, S.2    Cañedo, F.V.3
  • 21
    • 57049152303 scopus 로고    scopus 로고
    • Macdougall IC, Walker R, Provenzano R et al. C.E.R.A. (continuous erythropoietin receptor activator) administered at extended intervals corrects anemia and maintains stable Hb levels in patients with CKD not on dialysis. J Am Soc Nephrol 2006; 17: 619A (Abstract SA-PO208).
    • Macdougall IC, Walker R, Provenzano R et al. C.E.R.A. (continuous erythropoietin receptor activator) administered at extended intervals corrects anemia and maintains stable Hb levels in patients with CKD not on dialysis. J Am Soc Nephrol 2006; 17: 619A (Abstract SA-PO208).
  • 22
    • 33751002326 scopus 로고    scopus 로고
    • CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia
    • Drueke TB, Locatelli F, Clyne N, et al., CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006; 355: 2071-2084.
    • (2006) N Engl J Med , vol.355 , pp. 2071-2084
    • Drueke, T.B.1    Locatelli, F.2    Clyne, N.3
  • 23
    • 33750983605 scopus 로고    scopus 로고
    • CHOIR Investigators. Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh AK, Szczech L, Tang KL, et al., CHOIR Investigators. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006; 355: 2085-2098.
    • (2006) N Engl J Med , vol.355 , pp. 2085-2098
    • Singh, A.K.1    Szczech, L.2    Tang, K.L.3
  • 24
    • 0032477808 scopus 로고    scopus 로고
    • Human erythropoietin dimers with markedly enhanced in vivo activity
    • Sytkowski AJ, Lunn ED, Davis KL et al. Human erythropoietin dimers with markedly enhanced in vivo activity. Proc Natl Acad Sci USA 1998; 95: 1184-1188.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1184-1188
    • Sytkowski, A.J.1    Lunn, E.D.2    Davis, K.L.3
  • 25
    • 0035877998 scopus 로고    scopus 로고
    • Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo
    • Dalle B, Henri A, Rouyer-Fessard P et al. Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo. Blood 2001; 97: 3776-3782.
    • (2001) Blood , vol.97 , pp. 3776-3782
    • Dalle, B.1    Henri, A.2    Rouyer-Fessard, P.3
  • 26
    • 34748812412 scopus 로고    scopus 로고
    • Development of a long-acting erythropoietin by fusing the carboxyl-terminal peptide of human chorionic gonadotropin beta-subunit to the coding sequence of human erythropoietin
    • Fares F, Ganem S, Hajouj T et al. Development of a long-acting erythropoietin by fusing the carboxyl-terminal peptide of human chorionic gonadotropin beta-subunit to the coding sequence of human erythropoietin. Endocrinology 2007; 148: 5081-5087.
    • (2007) Endocrinology , vol.148 , pp. 5081-5087
    • Fares, F.1    Ganem, S.2    Hajouj, T.3
  • 27
    • 33748809512 scopus 로고    scopus 로고
    • Biochemical characterization of rhEpo-Fc fusion protein expressed in CHO cells
    • Schriebl K, Trummer E, Lattenmayer C et al. Biochemical characterization of rhEpo-Fc fusion protein expressed in CHO cells. Protein Expr Purif 2006; 49: 265-275.
    • (2006) Protein Expr Purif , vol.49 , pp. 265-275
    • Schriebl, K.1    Trummer, E.2    Lattenmayer, C.3
  • 28
    • 21044443734 scopus 로고    scopus 로고
    • Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond
    • Way JC, Lauder S, Brunkhorst B et al. Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond. Protein Eng Des Sel 2005; 18: 111-118.
    • (2005) Protein Eng Des Sel , vol.18 , pp. 111-118
    • Way, J.C.1    Lauder, S.2    Brunkhorst, B.3
  • 29
    • 25844528107 scopus 로고    scopus 로고
    • Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway
    • Dumont JA, Bitonti AJ, Clark D et al. Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway. J Aerosol Med 2005; 18: 294-303.
    • (2005) J Aerosol Med , vol.18 , pp. 294-303
    • Dumont, J.A.1    Bitonti, A.J.2    Clark, D.3
  • 30
    • 0037423148 scopus 로고    scopus 로고
    • Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein
    • Kochendoerfer GG, Chen SY, Mao F et al. Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein. Science 2003; 299: 884-887.
    • (2003) Science , vol.299 , pp. 884-887
    • Kochendoerfer, G.G.1    Chen, S.Y.2    Mao, F.3
  • 31
    • 20144371341 scopus 로고    scopus 로고
    • Synthetic erythropoietic proteins: Tuning biological performance by site-specific polymer attachment
    • Chen SY, Cressman S, Mao F et al. Synthetic erythropoietic proteins: tuning biological performance by site-specific polymer attachment. Chem Biol 2005; 12: 371-383.
    • (2005) Chem Biol , vol.12 , pp. 371-383
    • Chen, S.Y.1    Cressman, S.2    Mao, F.3
  • 32
    • 0032469128 scopus 로고    scopus 로고
    • The rhGM-CSF-EPO hybrid protein MEN 11300 induces anti-EPO antibodies and severe anaemia in rhesus monkeys
    • Coscarella A, Liddi R, Di Loreto M et al. The rhGM-CSF-EPO hybrid protein MEN 11300 induces anti-EPO antibodies and severe anaemia in rhesus monkeys. Cytokine 1998; 10: 964-969.
    • (1998) Cytokine , vol.10 , pp. 964-969
    • Coscarella, A.1    Liddi, R.2    Di Loreto, M.3
  • 33
    • 33748690610 scopus 로고    scopus 로고
    • Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia
    • Fan Q, Leuther KK, Holmes CP et al. Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia. Exp Hematol 2006; 34: 1303-1311.
    • (2006) Exp Hematol , vol.34 , pp. 1303-1311
    • Fan, Q.1    Leuther, K.K.2    Holmes, C.P.3
  • 34
    • 34447636387 scopus 로고    scopus 로고
    • Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model
    • Woodburn KW, Fan Q, Winslow S et al. Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model. Exp Hematol 2007; 35: 1201-1208.
    • (2007) Exp Hematol , vol.35 , pp. 1201-1208
    • Woodburn, K.W.1    Fan, Q.2    Winslow, S.3
  • 35
    • 57049083446 scopus 로고    scopus 로고
    • NCT00314795 registered on the clinicaltrial.gov website.
    • NCT00314795 registered on the clinicaltrial.gov website.
  • 36
    • 39649085543 scopus 로고    scopus 로고
    • CNTO 530: Molecular pharmacology in human UT-7EPO cells and pharmacokinetics and pharmacodynamics in mice
    • Bugelski PJ, Capocasale RJ, Makropoulos D et al. CNTO 530: molecular pharmacology in human UT-7EPO cells and pharmacokinetics and pharmacodynamics in mice. J Biotechnol 2008; 134: 171-180.
    • (2008) J Biotechnol , vol.134 , pp. 171-180
    • Bugelski, P.J.1    Capocasale, R.J.2    Makropoulos, D.3
  • 37
    • 30444445382 scopus 로고    scopus 로고
    • Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
    • Safran M, Kim WY, O'Connell F et al. Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production. Proc Natl Acad Sci USA 2006; 103: 105-110.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 105-110
    • Safran, M.1    Kim, W.Y.2    O'Connell, F.3
  • 38
    • 1642535393 scopus 로고    scopus 로고
    • Hepatic erythropoietin gene regulation by GATA-4
    • Dame C, Sola MC, Lim K-C et al. Hepatic erythropoietin gene regulation by GATA-4. J Biol Chem 2004; 279: 2955-2961.
    • (2004) J Biol Chem , vol.279 , pp. 2955-2961
    • Dame, C.1    Sola, M.C.2    Lim, K.-C.3
  • 39
    • 0031043063 scopus 로고    scopus 로고
    • Negative regulation of the erythropoietin gene expression by the GATA transcription factors
    • Imagawa S, Yamamoto M, Miura Y. Negative regulation of the erythropoietin gene expression by the GATA transcription factors. Blood 1997; 89: 1430-1439.
    • (1997) Blood , vol.89 , pp. 1430-1439
    • Imagawa, S.1    Yamamoto, M.2    Miura, Y.3
  • 40
    • 10244260353 scopus 로고    scopus 로고
    • Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anaemia of chronic disease
    • Nakano Y, Imagawa S, Matsumoto K et al. Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anaemia of chronic disease. Blood 2004; 104: 4300-4307.
    • (2004) Blood , vol.104 , pp. 4300-4307
    • Nakano, Y.1    Imagawa, S.2    Matsumoto, K.3
  • 41
    • 0028956353 scopus 로고
    • Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
    • Klingmuller U, Lorenz U, Cantley LC et al. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995; 80: 729-738.
    • (1995) Cell , vol.80 , pp. 729-738
    • Klingmuller, U.1    Lorenz, U.2    Cantley, L.C.3
  • 42
    • 0033019186 scopus 로고    scopus 로고
    • Defective expression of the SHP-1 phosphatase in polycythemia vera
    • Wickrema A, Chen F, Namin F et al. Defective expression of the SHP-1 phosphatase in polycythemia vera. Exp Hematol 1999; 27: 1124-1132.
    • (1999) Exp Hematol , vol.27 , pp. 1124-1132
    • Wickrema, A.1    Chen, F.2    Namin, F.3
  • 43
    • 9644266699 scopus 로고    scopus 로고
    • The critical role of SRC homology domain 2-containing tyrosine phosphatase-1 in recombinant human erythropoietin hyporesponsive anemia in chronic hemodialysis patients
    • Akagi S, Ichikawa H, Okada T et al. The critical role of SRC homology domain 2-containing tyrosine phosphatase-1 in recombinant human erythropoietin hyporesponsive anemia in chronic hemodialysis patients. J Am Soc Nephrol 2004; 15: 3215-3224.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 3215-3224
    • Akagi, S.1    Ichikawa, H.2    Okada, T.3
  • 44
    • 34247208149 scopus 로고    scopus 로고
    • Progress toward a nonviral gene therapy protocol for the treatment of anemia
    • Sebestyén MG, Hegge JO, Noble MA et al. Progress toward a nonviral gene therapy protocol for the treatment of anemia. Hum Gene Ther 2007; 18: 269-285.
    • (2007) Hum Gene Ther , vol.18 , pp. 269-285
    • Sebestyén, M.G.1    Hegge, J.O.2    Noble, M.A.3
  • 45
    • 20044392832 scopus 로고    scopus 로고
    • Gene electro-transfer on an improved erythropoietin plasmid in mice and non-human primates
    • Fattori E, Cappelletti M, Zampaglione I et al. Gene electro-transfer on an improved erythropoietin plasmid in mice and non-human primates. J Gene Med 2005; 7: 228-236.
    • (2005) J Gene Med , vol.7 , pp. 228-236
    • Fattori, E.1    Cappelletti, M.2    Zampaglione, I.3
  • 46
    • 33646903235 scopus 로고    scopus 로고
    • Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure
    • Eliopoulos N, Gagnon RF, Francois M et al. Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure. J Am Soc Nephrol 2006; 17: 1576-1584.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1576-1584
    • Eliopoulos, N.1    Gagnon, R.F.2    Francois, M.3
  • 47
    • 33748702530 scopus 로고    scopus 로고
    • Correction of anemia in uremic rats by intramuscular injection of lentivirus carrying an erythropoietin gene
    • Oh TK, Quan GH, Kim HY et al. Correction of anemia in uremic rats by intramuscular injection of lentivirus carrying an erythropoietin gene. Am J Nephrol 2006; 26: 326-334.
    • (2006) Am J Nephrol , vol.26 , pp. 326-334
    • Oh, T.K.1    Quan, G.H.2    Kim, H.Y.3
  • 48
    • 18844424225 scopus 로고    scopus 로고
    • Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts
    • Kakeda M, Hiratsuka M, Nagata K et al. Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts. Gene Ther 2005; 12: 852-856.
    • (2005) Gene Ther , vol.12 , pp. 852-856
    • Kakeda, M.1    Hiratsuka, M.2    Nagata, K.3
  • 49
    • 57049106770 scopus 로고    scopus 로고
    • Heifets M, Dougherty FC, Beyer U et al. on behalf of the PROTOS, MAXIMA, STRIATA and RUBRA study investigators. Hemoglobin (Hb) decline after withholding CERA. Administration is not influenced by the long half life of CERA. Abstract presented at the World Congress of Nephrology, 2007.
    • Heifets M, Dougherty FC, Beyer U et al. on behalf of the PROTOS, MAXIMA, STRIATA and RUBRA study investigators. Hemoglobin (Hb) decline after withholding CERA. Administration is not influenced by the long half life of CERA. Abstract presented at the World Congress of Nephrology, 2007.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.