Defective expression of the SHP-1 phosphatase in polycythemia vera

Experimental Hematology

Volumn 27, Issue 7, 1999, Pages 1124-1132

  Wickrema, Amittha ^a   Chen, Fei ^a   Namin, Farid ^a   Yi, Taolin ^b   Ahmad, Sarfraz ^a   Uddin, Shahab ^a   Chen, Yi Hsiang ^a   Feldman, Lawrence ^a   Stock, Wendy ^a   Hoffman, Ronald ^a   Platanias, Leonidas C ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Erythroid progenitors; Polycythemia vera; SHP 1

Indexed keywords

ERYTHROPOIETIN; GROWTH FACTOR; INTERLEUKIN 3; LIGAND; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE; STEM CELL FACTOR;

ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; GROWTH REGULATION; HUMAN; MITOGENESIS; PATHOGENESIS; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL DIFFERENTIATION; COLONY-FORMING UNITS ASSAY; ENZYME INDUCTION; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN; HEME; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; POLYCYTHEMIA VERA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, ERYTHROPOIETIN; RECEPTORS, INTERLEUKIN-3; RNA, MESSENGER; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 0033019186     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(99)00043-0     Document Type: Article

References (38)

1. Adachi M., Fischer E.H., Ihle J.N., Imani K., Jirik F., Neel B., Pawson T., Shen S., Thomas M., Ulrich A., Zhao Z. Mammalian SH2-containing protein tyrosine phosphatases. Cell. 85:1996;15.
2. Shen S.H., Bastien L., Posner B., Chretien P. A protein Tyrosine Phosphatase with sequence similarity to the SH2 domain of the protein tyrosine kinases. Nature. 352:1991;736.
3. Mathew R.J., Browne B., Flores E., Thomas M.L. Characterization of hematopoietic intracellular protein tyrosine phosphatases. description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, threonine-rich sequences Mol Cell Biol. 12:1992;2396.
4. Plutzky J., Neel B.G., Rosenberg R.D. Isolation of a src homology 2 containing tyrosine phosphatase. Proc Natl Acad Sci U S A. 89:1992;1123.
5. Yi T.L., Cleveland J.L., Ihle J.N. Protein tyrosine phosphatase containing SH2 domains. characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12 p 12-13 Mol Cell Biol. 12:1992;836.
6. Pei D., Wang J., Walsh C.T. Differential functions of the two src homology 2 domains in protein tyrosine phosphatase SH-PTP1. Proc Natl Acad Sci U S A. 93:1996;1141.
7. Krantz S.B. Erythropoietin. Blood. 77:1991;419.
8. Wickrema A., Krantz S.B., Winkelmann J.C., Bondurant M.C. Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells. Blood. 80:1992;1940.
9. Muta K., Krantz S.B., Bondurant M.C., Wickrema A. Distinct roles of erythropoietin, insulin-like growth factor-1 and stem cell factor in the development of erythroid progenitor cells. J Clin Invest. 94:1994;34.
10. Lorenz U., Bergemann A.D., Steinberg H.N., Flanagan J.G., Li X., Galli S.J., Neel B.G. Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-kit by the protein tyrosine phosphatase SHP-1. J Exp. Med. 184:1996;1111.
11. Klingmuller U., Lorenz U., Cantley L.C., Neel B.G., Lodish H. Specific recruitment of SH-PTPI to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell. 80:1995;729.
12. Yi T., Ihle J.N. Association of hematopoietic cell phosphatase with c-kit after stimulation with c-kit ligand. Mol Cell Biol. 13:1993;3350.
13. Yi T., Mui A.L., Krystal G., Ihle J.N. Hematopoietic cell phosphatase associates with the interleukin-3 (IL3) receptor beta chain and down regulates IL3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol. 13:1993;7577.
14. Yi T., Zhang J., Miura O., Ihle J.N. Hematopoietic cell phosphatase associates with erythropoietin (EPO) receptor after EPO-induced receptor tyrosine phosphorylation. identification of potential binding sites Blood. 85:1995;87.
15. Jiao H., Berrada K., Yang W., Tabrizi Platanias L.C., Yi T. Direct association with and dephosphorylation of Jak2 kinase by the SH-2- domain- containing protein tyrosine phosphatase SHP-1. Mol Cell Biol. 16:1996;6985.
16. Yetter A., Uddin S., Krolewski J.J., Jiao H., Yi T., Platanias L.C. Association of the interferon-dependent tyrosine kinase tyk-2 with the hematopoietic cell phosphatase. J Biol Chem. 270:1995;18179.
17. David M., Chen H.E., Goelz S., Larner A.C., Neel B.G. Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1. Mol Cell Biol. 15:1995;7050.
18. Paulson R.F., Siminovitch K.A., Bernstein A. Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase SHP1. Nat Genet. 13:1996;309.
19. Zanjani E.D., Lutton J.D., Hoffman R., Wasserman L.R. Erythroid colony formation by polycythemia vera bone marrow in vitro. dependence on erythropoietin J Clin Invest. 59:1977;841.
20. Eaves C.J., Eaves A.C. Erythropoietin dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera. Blood. 52:1978;1196.
21. Casadevall N., Vaincheker W., LaComte C. Erythroid progenitors in polycythemia vera. demonstration of their hypersensitivity to erythropoietin in serum free cultures Blood. 59:1982;447.
22. Dai C.-H., Krantz S.B., Means R.T., Horn W.T., Gilbert H.S. Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3. J Clin Invest. 87:1991;391.
23. Dai C.-H., Krantz S.B., Green W.F., Gilbert H.S. Polycythemia vera III. Burst-forming units-erythroid (BFU-E) response to stem cell factor and c-kit receptor expression. Br J Hematol. 86:1994;12.
24. Correa P.N., Eskinazi D., Axelrad A.A. Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro. Studies in an improved serum-free medium. Blood. 83:1994;99.
25. Dai C.-H., Krantz S.B., Koury S.T., Kollar K. Polycythemia vera-IV. Specific binding of stem cell factor to normal and polycythemia vera highly purified erythroid progenitor cells. Br J Haematol. 88:1994;497.
26. Hess G., Rose P., Gamm H. Molecular analysis of the erythropoietin receptor system in patients with polycythemia vera. Br J Haematol. 88:1994;794.
27. Le Couedic J.P., Mitjavila M.T., Villeval J.L., Feger F., Gobert S., Mayeux P., Casadevall N., Vainchenker W. Missense mutation of the erythropoietin receptor is a rare event in human erythroid malignancies. Blood. 87:1996;1502.
28. Berlin N.I. Diagnosis and classification of the polycythemias. Semin Hematol. 12:1975;339.
29. Wickrema A., Koury S.T., Dai C.-H., Krantz S.B. Changes in cytoskelatal proteins and their mRNAs during maturation of human erythroid progenitor cells. J Cell Physiol. 160:1994;417.
30. v). Exp Hematol. 17:1989;81.
31. Shultz L.D., Schweitzer Rajan T.V., Yi T., Ihle J.N., Mathews R.J., Thomas M.L., Beier D.R. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell. 73:1993;1445.
32. Dai C.-H., Krantz S.B., Sawyer S.T. Polycythemia vera V. Enhanced proliferation and phosphorylation due to vandate care diminished in polycythemia vera erythroid progenitor cells. A possible defect of phosphatase activity in polycythemia vera. Blood. 89:1997;3574.
33. Fisher M.J., Prachal J.F., Prchal J.T., D'Andrea A.D. Anti-Erythropoietin (EPO) receptor monoclonal antibodies distinguish EPO-dependent and EPO-independent erythroid progenitors in polycythemia vera. Blood. 84:1994;1982.
34. Sharlow E.R., Pacifici J.C., Batac J., Kazuo T., Wojchowski D.M. Hematopoietic cell phosphatase negatively regulates erythropoietin-induced hemoglobinization in erythroleukemic SKT6 cells. Blood. 90:1997;2175.
35. Sui X., Krantz S.B., Zhao Z. Identification of increased protein tyrosine phosphatase activity in polycythemia vera erythroid progenitor cells. Blood. 90:1997;651.
36. Asimakopoulos F.A., Hinshelwood S., Gilbert J.G.R., Delibrias C.C., Gottgens B., Fearon D.T., Green A.R. The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera. Oncogene. 14:1997;1215.
37. Anderson P., Le Blanc K., Eriksson B.-A., Samuelson J. No evidence for an altered mRNA expression or protein level of hematopoietic cell phosphatase in CD34+ bone marrow progenitor cells or mature peripheral blood cells in polycythemia vera. Eur J Haematol. 59:1997;310.
38. Chiba S., Takahashi T., Takeshita K., Minowada J., Yazaki Y., Ruddle F.H., Hirai H. Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera. Blood. 90:1994;97.