Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 673, Issue 2, 2009, Pages 92-99

  Mun, Greg C ^a   Aardema, Marilyn J ^b   Hu, Ting ^b   Barnett, Brenda ^c   Kaluzhny, Yulia ^d   Klausner, Mitchell ^d   Karetsky, Viktor ^d   Dahl, Erica L ^a   Curren, Rodger D ^a  

^a Institute for in Vitro Sciences   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c Advanced Testing Laboratory   (United States)

^d MATTEK CORPORATION   (United States)

Author keywords

3D human skin model; Genotoxicity; In vitro skin micronucleus assay

Indexed keywords

CARCINOGEN; CYTOCHALASIN B; MITOMYCIN C; MUTAGENIC AGENT;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MICRONUCLEUS TEST; PHYSICAL MODEL; PRIORITY JOURNAL; SKIN TEST; ANIMAL TESTING ALTERNATIVE; CALIBRATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; EPIDERMIS; EVALUATION; HUMAN; METHODOLOGY; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; SKIN; TIME; TISSUE ENGINEERING; TOXICITY TESTING;

ANIMALIA; RODENTIA;

ANIMAL TESTING ALTERNATIVES; CALIBRATION; CYTOCHALASIN B; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMIS; HUMANS; MICRONUCLEUS TESTS; MUTAGENS; SENSITIVITY AND SPECIFICITY; SKIN; SKIN IRRITANCY TESTS; TIME FACTORS; TISSUE ENGINEERING;

EID: 61449252431     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.12.004     Document Type: Article

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