Activation of aminoimidazole carcinogens by nitrosation: Mutagenicity and nucleotide adducts

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 673, Issue 2, 2009, Pages 109-115

  Zenser, Terry V ^a   Lakshmi, Vijaya M ^a   Schut, Herman A J ^b   Zhou, Hui jia ^c   Josephy, P David ^c  

^a SAINT LOUIS UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

2 Nitrosoamino 3,8 dimethylimidazo 4,5 f quinoxaline; 2 Nitrosoamino 3 methylimidazo 4,5 f quinoline; Heterocyclic amines; Mutagenicity; Nitrosation; Nucleotide adducts

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; ACYLTRANSFERASE; BETA GALACTOSIDASE; CARCINOGEN; CYTOCHROME P450 1A2; DEOXYGUANOSINE DERIVATIVE; DNA; MUTAGENIC AGENT; NITROSAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ARTICLE; CARCINOGENESIS; COLITIS; COLON CANCER; CONTROLLED STUDY; COOKING; ESCHERICHIA COLI; FOOD INTAKE; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MUTAGENICITY; NITROSATION; NONHUMAN; PRIORITY JOURNAL; RED MEAT; SALMONELLA TYPHIMURIUM;

CARCINOGENS; CELLS, CULTURED; DNA ADDUCTS; HUMANS; IMIDAZOLES; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; NITRATES; NITROSATION; NUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 61449180086     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.12.007     Document Type: Article

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