Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 79, Issue 6, 2008, Pages 201-207

  Qin, Qiong ^a   Patil, Kiran A ^a   Gronert, Karsten ^b   Sharma, Sansar C ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

12 15 Lipoxygenase; Docosahexaenoic acid; Retinal ganglion cell

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; DOCOSAHEXAENOIC ACID; NEUROPROTECTIN D1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL DENSITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; FEMALE; GENE AMPLIFICATION; MALE; MOUSE; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; UPREGULATION;

ANIMALS; ARACHIDONATE 15-LIPOXYGENASE; AXOTOMY; CELL DEATH; CELL SURVIVAL; DOCOSAHEXAENOIC ACIDS; FEMALE; GENE EXPRESSION; MALE; RATS; RATS, WISTAR; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

MUS; RATTUS;

EID: 61349175804     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2008.09.022     Document Type: Article

References (54)

1. Berkelaar M., Clarke D.B., Wang Y.C., Bray G.M., and Aguayo A.J. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J. Neurosci. 14 (1994) 4368-4374
2. Garcia-Valenzuela E., Gorczyca W., Darzynkiewicz Z., and Sharma S.C. Apoptosis in adult retinal ganglion cells after axotomy. J. Neurobiol. 25 (1994) 431-438
3. Neuringer M., Connor W.E., Van Petten C., and Barstad L. Dietary omega-3 fatty acid deficiency and visual loss in infant rhesus monkeys. J. Clin. Invest. 73 (1984) 272-276
4. M. Neuringer, W.E. Connor, D.S. Lin, L. Barstad, S. Luck, Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys, in: Proceedings of the National Academic Science, USA, vol. 83, 1986, pp. 4021-4025.
5. Neuringer M., Anderson G.J., and Connor W.E. The essentiality of n-3 fatty acids for the development and function of the retina and brain. Annu. Rev. Nutr. 8 (1988) 517-541
6. Uauy R., Peirano P., Hoffman D., Mena P., Birch D., and Birch E. Role of essential fatty acids in the function of the developing nervous system. Lipids 31 suppl. (1996) S167-S176
7. Kim H.Y., Akbar M., Lau A., and Edsall L. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J. Biol. Chem. 275 (2000) 35215-35223
8. Rotstein N.P., Aveldano M.I., Barrantes F.J., Roccamo A.M., and Politi L.E. Apoptosis of retinal photoreceptors during development in vitro: protective effect of docosahexaenoic acid. J. Neurochem. 69 (1997) 504-513
9. Rotstein N.P., Politi L.E., German O.L., and Girotti R. Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2252-2259
10. Arterburn L.M., Hall E.B., and Oken H. Distribution, interconversion, and dose response of n-3 fatty acids in humans. Am. J. Clin. Nutr. 83 (2006) 1467S-1476S
11. Mirnikjoo B., Brown S.E., Kim H.F., Marangell L.B., Sweatt J.D., and Weeber E.J. Protein kinase inhibition by omega-3 fatty acids. J. Biol. Chem. 276 (2001) 10888-10896
12. McGahon B.M., Martin D.S., Horrobin D.F., and Lynch M.A. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience 94 (1999) 305-314
13. Gamoh S., Hashimoto M., Sugioka K., et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience 93 (1999) 237-241
14. Gordon W.C., and Bazan N.G. Docosahexaenoic acid utilization during rod photoreceptor cell renewal. J. Neurosci. 10 (1990) 2190-2202
15. Lauritzen I., Blondeau N., Heurteaux C., Widmann C., Romey G., and Lazdunski M. Polyunsaturated fatty acids are potent neuroprotectors. EMBO J. 19 (2000) 1784-1793
16. Rodriguez de Turco E.B., Belayev L., Liu Y., et al. Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albumin. J. Neurochem. 83 (2002) 515-524
17. Lim G.P., Calon F., Morihara T., et al. A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J. Neurosci. 25 (2005) 3032-3040
18. Aveldano M.I., and Bazan N.G. Differential lipid deacylation during brain ischemia in a homeotherm and a poikilotherm. Content and composition of free fatty acids and triacylglycerols. Brain Res. 100 (1975) 99-110
19. Bazan Jr. N.G. Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim. Biophys. Acta 218 (1970) 1-10
20. Bazan N.G. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Curr. Opin. Clin. Nutr. Metab. Care 10 (2007) 136-141
21. Birkle D.L., and Bazan N.G. Effect of bicuculline-induced status epilepticus on prostaglandins and hydroxyeicosatetraenoic acids in rat brain subcellular fractions. J. Neurochem. 48 (1987) 1768-1778
22. Duffield J.S., Hong S., Vaidya V.S., et al. Resolvin D series and protectin D1 mitigate acute kidney injury. J. Immunol. 177 (2006) 5902-5911
23. Hong S., Gronert K., Devchand P.R., Moussignac R.L., and Serhan C.N. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J. Biol. Chem. 278 (2003) 14677-14687
24. Marcheselli V.L., Hong S., Lukiw W.J., et al. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J. Biol. Chem. 278 (2003) 43807-43817
25. Serhan C.N. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol. 25 (2007) 101-137
26. Serhan C.N., Gotlinger K., Hong S., et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J. Immunol. 176 (2006) 1848-1859
27. Lukiw W.J., Cui J.G., Marcheselli V.L., et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J. Clin. Invest. 115 (2005) 2774-2783
28. Gronert K., Maheshwari N., Khan N., Hassan I.R., Dunn M., and Laniado S.M. A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense. J. Biol. Chem. 280 (2005) 15267-15278
29. P.K. Mukherjee, V.L. Marcheselli, C.N. Serhan, N.G. Bazan, Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress, in: Proceedings of the National Academy of Science, USA, vol. 101, 2004, pp. 8491-8496.
30. Cyrus T., Witztum J.L., Rader D.J., et al. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J. Clin. Invest. 103 (1999) 1597-1604
31. Funk C.D., Chen X.S., Johnson E.N., and Zhao L. Lipoxygenase genes and their targeted disruption. Prostag. Other Lipid Mediat. 68-69 (2002) 303-312
32. Klein R.F., Allard J., Avnur Z., et al. Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science 303 (2004) 229-232
33. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1986), Academic Press, New York
34. Paxinos G., and Franklin K. The Mouse Brain in Stereotaxic Coordinates (1997), Academic Press, San Diego
35. Biteman B., Hassan I.R., Walker E., et al. Interdependence of lipoxin A4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing. FASEB J. 21 (2007) 2257-2266
36. Gronert K., Clish C.B., Romano M., and Serhan C.N. Transcellular regulation of eicosanoid biosynthesis. Methods Mol. Biol. 120 (1999) 119-144
37. Murphy R.C., Barkley R.M., Zemski B.K., et al. Electrospray ionization and tandem mass spectrometry of eicosanoids. Anal. Biochem. 346 (2005) 1-42
38. Serhan C.N., Hong S., Gronert K., et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196 (2002) 1025-1037
39. Serhan C.N. Novel eicosanoid and docosanoid mediators: resolvins, docosatrienes, and neuroprotectins. Curr. Opin. Clin. Nutr. Metab. Care 8 (2005) 115-121
40. Serhan C.N., Chiang N., and Van Dyke T.E. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8 (2008) 349-361
41. Young R.W. Cell death during differentiation of the retina in the mouse. J. Comp. Neurol. 229 (1984) 362-373
42. Penfold P.L., and Provis J.M. Cell death in the development of the human retina: phagocytosis of pyknotic and apoptotic bodies by retinal cells. Graef. Arch. Clin. Exp. Ophthalmol. 224 (1986) 549-553
43. Kelavkar U., Glasgow W., and Eling T.E. The effect of 15-lipoxygenase-1 expression on cancer cells. Curr. Urol. Rep. 3 (2002) 207-214
44. Middleton M.K., Zukas A.M., Rubinstein T., et al. Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease. J. Exp. Med. 203 (2006) 2529-2540
45. Shappell S.B., Olson S.J., Hannah S.E., et al. Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma. Cancer Res. 63 (2003) 2256-2267
46. Sharma G.D., Ottino P., Bazan N.G., and Bazan H.E. Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Calpha translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis. J. Biol. Chem. 280 (2005) 7917-7924
47. Conquer J.A., Tierney M.C., Zecevic J., Bettger W.J., and Fisher R.H. Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment. Lipids 35 (2000) 1305-1312
48. Kyle D.J., Schaefer E., Patton G., and Beiser A. Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia. Lipids 34 suppl. (1999) S245
49. Calon F., Lim G.P., Morihara T., et al. Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease. Eur. J. Neurosci. 22 (2005) 617-626
50. Bazan N.G. Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors. Trends Neurosci. 29 (2006) 263-271
51. K. Gronert, I.R. Hassan, Reaping the Benefits of Renal Protective Lipid Autacoids, in: Drug Discovery Today: Disease Mechanisms, Vol. 4, No. 1, 2007, pp. 3-10.
52. Connor K.M., SanGiovanni J.P., Lofqvist C., et al. Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nat. Med. 13 (2007) 868-873
53. Garcia-Valenzuela E., Sharma S.C., and Pina A.L. Multilayered retinal microglial response to optic nerve transection in rats. Mol. Vis. 11 (2005) 225-231
54. Qin Q., Patil K., and Sharma S.C. The role of Bax-inhibiting peptide in retinal ganglion cell apoptosis after optic nerve transection. Neurosci. Lett. 372 (2004) 17-21