Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist

Experimental Hematology

Volumn 33, Issue 1, 2005, Pages 85-93

  Erickson Miller, Connie L ^a,c   DeLorme, Evelyne ^b   Tian, Shin Shay ^b   Hopson, Christopher B ^a   Stark, Kenneth ^a   Giampa, Leslie ^b   Valoret, Elizabeth I ^a   Duffy, Kevin J ^a   Luengo, Juan L ^a   Rosen, Jon ^b   Miller, Stephen G ^b   Dillon, Susan B ^a   Lamb, Peter ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b LIGAND PHARMACEUTICALS INC   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CYTOKINE RECEPTOR AGONIST; ERYTHROPOIETIN; FIBRINOGEN RECEPTOR; GAMMA INTERFERON; GLYCOPROTEIN IIB; GRANULOCYTE COLONY STIMULATING FACTOR; HYDRAZONE DERIVATIVE; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SB 394725; STAT5 PROTEIN; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOG; EARLY RESPONSE GENE; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RABBIT; REPORTER GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOOD PLATELETS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; DNA-BINDING PROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; HYDRAZONES; MEGAKARYOCYTES; MICE; MILK PROTEINS; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, THROMBOPOIETIN; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

CANIS FAMILIARIS; MACACA FASCICULARIS; ORYCTOLAGUS CUNICULUS;

EID: 19944432021     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2004.09.006     Document Type: Article

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