Inactivation of Pkd1 in principal cells causes a more severe cystic kidney disease than in intercalated cells

Kidney International

Volumn 75, Issue 6, 2009, Pages 626-633

  Raphael, Kalani L ^a   Strait, Kevin A ^a   Stricklett, Peter K ^a   Miller, R Lance ^a   Nelson, Raoul D ^a   Piontek, Klaus B ^b   Germino, Gregory G ^b   Kohan, Donald E ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Collecting duct; Cre recombinase; Gene targeting; Polycystin 1

Indexed keywords

AQUAPORIN 2; CRE RECOMBINASE; CYCLIC AMP; POLYCYSTIN 1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE DELETION; GENE INACTIVATION; INTRON; KIDNEY CORTEX; KIDNEY CYST; KIDNEY MEDULLA; KIDNEY PAPILLA; KIDNEY POLYCYSTIC DISEASE; LIFESPAN; MALE; MORTALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; KIDNEY CORTEX; KIDNEY DISEASES, CYSTIC; KIDNEY MEDULLA; KIDNEY TUBULES, COLLECTING; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; TRPP CATION CHANNELS;

EID: 61349143028     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.659     Document Type: Article

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