7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases

Autoimmunity Reviews

Volumn 8, Issue 5, 2009, Pages 369-372

  Auci, Dominick L ^a   Reading, Christopher L ^a   Frincke, James M ^a  

^a Hollis Eden Pharmaceuticals Inc   (United States)

Author keywords

7 Hydroxy DHEA; Androstenediol; Steroids; TRIOLEX

Indexed keywords

17ALPHA ETHINYL 5 ANDROSTENE 3BETA,7BETA,17BETA TRIOL; 7 HYDROXYANDROSTENE DERIVATIVE; ANDROGEN; ANDROSTANE DERIVATIVE; ANDROSTENEDIOL; ESTROGEN; HE 3286; OXYGEN DERIVATIVE; TRIOLEX; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AUTOIMMUNE DISEASE; CLINICAL TRIAL; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG SPECIFICITY; DRUG STABILITY; DRUG SYNTHESIS; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RAT; REVIEW; RISK REDUCTION; STEROID THERAPY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CLINICAL TRIALS AS TOPIC; COLITIS; DEHYDROEPIANDROSTERONE; DISEASE MODELS, ANIMAL; HUMANS; MICE; PNEUMONIA; RATS; SHOCK, SEPTIC;

EID: 61349135573     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2008.11.011     Document Type: Review

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