Synovial fluid estrogens in rheumatoid arthritis

Autoimmunity Reviews

Volumn 3, Issue 3, 2004, Pages 193-198

  Cutolo, Maurizio ^a   Villaggio, Barbara ^a   Seriolo, Bruno ^a   Montagna, Paola ^a   Capellino, Silvia ^a   Straub, Rainer H ^b   Sulli, Alberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Estrogens; Inflammation; Rheumatoid arthritis; Synovial fluid; Synovial tissue

Indexed keywords

16ALPHA HYDROXYESTRONE; 2 HYDROXYESTROGEN DERIVATIVE; ANDROGEN; ESTROGEN; INTERLEUKIN 1; INTERLEUKIN 6; PRASTERONE; SEX HORMONE; STEROID HORMONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ESTROGEN METABOLISM; ESTROGEN THERAPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROXYLATION; IMMUNOMODULATION; PREVALENCE; REVIEW; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVITIS; SYNOVIUM;

ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; CYTOKINES; DEHYDROEPIANDROSTERONE; ESTRIOL; ESTROGENS; FEMALE; HUMANS; HYDROXYESTRONES; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; SEX FACTORS; SYNOVIAL FLUID; SYNOVITIS; T-LYMPHOCYTES;

EID: 1942521697     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2003.08.003     Document Type: Review

References (29)

1. Cutolo M., Villaggio B., Craviotto C., Pizzorni C., Seriolo B., Sulli A. Sex hormones and rheumatoid arthritis. Autoimmunity Rev. 1:2002;284-289.
2. Cutolo M., Carruba G., Villaggio B., Coviello D., Dayer J.M., Campisi I., et al. The phorbol diester 12-0-tetradecanoylphorbol 13-acetate (TPA) upregulates the expression of estrogen receptors in human THP-1 leukemia cells. J Cell Biochem. 83:2001;390-400.
3. Cutolo M., Villaggio B., Bisso A., Sulli A., Coviello D.A., Dayer J.M. Presence of estrogen receptors in human myeloid monocytic cells (THP-1 cell line). Eur Cytokine Netw. 12:2001;368-372.
4. Cutolo M., Accardo S., Villaggio B., Barone A., Sulli A., Coviello D.A., et al. Androgen and estrogen receptors are present in primary cultures of human synovial macrophages. J Clin Endocrinol Metab. 81:1996;820-827.
5. Straub R., Cutolo M. Impact of the hypothalamic-pituitary-adrenal/gonadal axes and the peripheral nervous system in rheumatoid arthritis: a systemic pathogenic view point. Arthritis Rheum. 44:2001;493-507.
6. Kanda N., Tsuchida T., Tamaki K. Estrogen enhancement of anti-double-stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Arthritis Rheum. 42:1999;328-337.
7. Hu S.K., Mitcho Y.L., Rath N.C. Effect of estradiol on interleukin 1 synthesis by macrophages. Int J Immunopharmacol. 10:1988;247-252.
8. Correale J., Arias M., Gilmore W. Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects. J Immunol. 161:1998;3365-3374.
9. Khalkhali-Ellis Z., Seftor E.A., Nieva D.R.C., Handa R.J., Price R.H. Jr, Kirschmann D.A., et al. Estrogen and progesterone regulation of human fibroblast-like synoviocyte function in vitro: implications in rheumatoid arthritis. J Rheumatol. 27:2000;1622-1631.
10. Kawasaki T., Ushiyama T., Inoue K., Hukuda S. Effects of estrogen on interleukin-6 production in rheumatoid fibroblast-like synoviocytes. Clin Exp Rheumatol. 18:2000;743-745.
11. Komi J., Mottonen M., Luukkainen R., Lassila O. Non-steroidal anti-oestrogens inhibit the differentiation of synovial macrophages into dendritic cells. Rheumatology (Oxford). 40:2001;185-191.
12. Masi A.T., Feigenbhaum S.L., Chatteron R.T. Hormonal and pregnancy relationship in RA: convergens effects with immunologic and microvascular systems. Semin Arthritis Rheum. 25:1995;1-7.
13. Bijlsma J.W.J., van der Brink H.R. Estrogens and rheumatoid arthritis. Am J Reprod Immunol. 28:1992;231-236.
14. Cutolo M., Sulli A., Villaggio B., Seriolo B., Accardo S. Relations between steroid hormones and cytokines in rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis. 57:1998;573-577.
15. Schmidt M., Kreutz M., Loffler G., Scholmerich J., Straub R.H. Conversion of dehydroepiandrosterone to downstream steroid hormones in macrophages. J Endocrinol. 164:2000;161-169.
16. Le Bail J.C., Lotfi H., Charles L., Pepin D., Habrioux G. Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells. Steroids. 67:2002;1057-1064.
17. Cutolo M., Balleari E., Giusti M., Monachesi M., Accardo S. Sex hormone status in women suffering from rheumatoid arthritis. J Rheumatol. 13:1986;1019-1023.
18. De LaTorre B., Hedman M., Olesen E., Thorner A. Relationship between blood and joint tissue DHEAS levels in rheumatoid arthritis and osteoarthritis. Clin Exp Rheumatol. 56:1997;281-284.
19. Nestler J.E. Interleukin-1 stimulates aromatase activity of human placental cytotrophoblasts. Endocrinology. 132:1993;566-570.
20. Macdiarmid F., Wang D., Duncan L.G. Stimulation of aromatase activity in breast fibroblasts by tumor necrosis factor α Mol Cell Endocrinol. 106:1994;17-21.
21. Purohit A, Ghilchic MW, Duncan L. Aromatase activity and interleukin-6 production by normal and malignant breast tissues. J Clin Endocrinol Metab 1995;80:3052-58
22. Le Bail J., Liagre B., Vergne P., Bertin P., Beneytout J., Habrioux G. Aromatase in synovial cells from postmenopausal women. Steroids. 66:2001;749-757.
23. Castagnetta L., Cutolo M., Granata O., Di Falco M., Bellavia V., Carruba G. Endocrine end-points in rheumatoid arthritis. Ann NY Acad Sci. 876:1999;180-192.
24. Castagnetta L, Carruba G, Granata OM, Schmidt M, Cutolo M, Straub RH et al. Increased estrogen formation and estrogen to androgen ratio in the SF of patients with rheumatoid arthritis. J Rheumatol 2003: (in press)
25. Swaneck G.E., Fishman J. Covalent binding of the endogenous estrogen 16 alpha-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA. 85:1988;7831-7835.
26. Telang N.T., Suto A., Wong G.Y., Osborne M.P., Bradlow H.L. Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells. J Natl Cancer Inst. 15:(84):1992;634-638.
27. Schneider J., Huh M.M., Bradlow H.L., Fishman J. Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem. 259:1984;4840-4845.
28. Bradlow H.L., Telang N.T., Sepkovic D.W., Osborne M.P. 2-hydroxyestrone: the 'good' estrogen. J Endocrinol. 150:(Suppl.):1996;S259-S265.
29. Cutolo M., Sulli A., Seriolo B., Accardo S., Masi A.T. Estrogens, the immune response and autoimmunity. Clin Exp Rheumatol. 13:1995;217-226.