-
1
-
-
0345898928
-
Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
-
10.1074/jbc.273.40.25875 9748262
-
Kim YH Choi CY Lee SJ Conti MA Kim Y Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors J Biol Chem 1998, 273:25875-25879. 10.1074/jbc.273.40.25875 9748262
-
(1998)
J Biol Chem
, vol.273
, pp. 25875-25879
-
-
Kim, Y.H.1
Choi, C.Y.2
Lee, S.J.3
Conti, M.A.4
Kim, Y.5
-
2
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
-
10.1038/ncb714 11780126
-
D'Orazi G Cecchinelli B Bruno T Manni I Higashimoto Y Saito S Gostissa M Coen S Marchetti A Del Sal G Piaggio G Fanciulli M Appella E Soddu S Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis Nature Cell Biol 2002, 4:11-19. 10.1038/ncb714 11780126
-
(2002)
Nature Cell Biol
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
Saito, S.6
Gostissa, M.7
Coen, S.8
Marchetti, A.9
Del Sal, G.10
Piaggio, G.11
Fanciulli, M.12
Appella, E.13
Soddu, S.14
-
3
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
10.1038/ncb715
-
Hofmann TG Moller A Sirma H Zebtgraft H Taya Y Droge W Will H Schmitz ML Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 Nauret Cell Biol 2002, 4:1-10. 10.1038/ncb715
-
(2002)
Nauret Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
Zebtgraft, H.4
Taya, Y.5
Droge, W.6
Will, H.7
Schmitz, M.L.8
-
4
-
-
45549086243
-
Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown
-
10.1158/0008-5472.CAN-07-6776 18483253
-
Puca R Nardinocchi L Gal H Rechavi G Amariglio N Domany E Notterman DA Scarsella M Leonetti C Sacchi A Blandino G Givol D D'Orazi G Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown Cancer Res 2008, 68:3707-3714. 10.1158/ 0008-5472.CAN-07-6776 18483253
-
(2008)
Cancer Res
, vol.68
, pp. 3707-3714
-
-
Puca, R.1
Nardinocchi, L.2
Gal, H.3
Rechavi, G.4
Amariglio, N.5
Domany, E.6
Notterman, D.A.7
Scarsella, M.8
Leonetti, C.9
Sacchi, A.10
Blandino, G.11
Givol, D.12
D'Orazi, G.13
-
5
-
-
0345830383
-
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis
-
10.1016/j.yexcr.2003.09.032 14729469
-
Di Stefano V Rinaldo C Sacchi A Soddu S D'Orazi G Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis Exp Cell Res 2004, 293:311-320. 10.1016/j.yexcr.2003.09.032 14729469
-
(2004)
Exp Cell Res
, vol.293
, pp. 311-320
-
-
Di Stefano, V.1
Rinaldo, C.2
Sacchi, A.3
Soddu, S.4
D'Orazi, G.5
-
6
-
-
34547108122
-
HIPK2 knock-down compromises tumor cell efficiency to repair damaged DNA
-
10.1016/j.bbrc.2007.07.031 17658469
-
Nardinocchi L Puca R Sacchi A D'Orazi G HIPK2 knock-down compromises tumor cell efficiency to repair damaged DNA Biochem Biophys Res Commun 2007, 361:249-255. 10.1016/j.bbrc.2007.07.031 17658469
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 249-255
-
-
Nardinocchi, L.1
Puca, R.2
Sacchi, A.3
D'Orazi, G.4
-
7
-
-
44549085662
-
Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells
-
10.1016/j.ygyno.2008.02.018 18395248
-
Puca R Nardinocchi L Pistritto G D'Orazi G Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells Gynecol Oncol 2008, 109:403-410. 10.1016/j.ygyno.2008.02.018 18395248
-
(2008)
Gynecol Oncol
, vol.109
, pp. 403-410
-
-
Puca, R.1
Nardinocchi, L.2
Pistritto, G.3
D'Orazi, G.4
-
8
-
-
32944456146
-
Homeodomain-interacting protein kinase-2 restrains cytosolic-phospholipase-A2-dependent prostaglandin-E2 generation in human colorectal cancer cells
-
10.1158/1078-0432.CCR-05-1557 16467083
-
D'Orazi G Sciulli MG Di Stefano V Riccioni S Frattini M Falcioni R Bertario L Sacchi A Patrignani P Homeodomain-interacting protein kinase-2 restrains cytosolic-phospholipase-A2-dependent prostaglandin-E2 generation in human colorectal cancer cells Clin Cancer Res 2006, 12:735-741. 10.1158/1078-0432.CCR-05-1557 16467083
-
(2006)
Clin Cancer Res
, vol.12
, pp. 735-741
-
-
D'Orazi, G.1
Sciulli, M.G.2
Di Stefano, V.3
Riccioni, S.4
Frattini, M.5
Falcioni, R.6
Bertario, L.7
Sacchi, A.8
Patrignani, P.9
-
10
-
-
52949128032
-
Regulation of vascular endothelial growth factor expression ny homeodomain-interacting protein kinase-2
-
2494538 18644116 10.1186/1756-9966-27-22
-
Puca R Nardinocchi L D'Orazi G Regulation of vascular endothelial growth factor expression ny homeodomain-interacting protein kinase-2 J Exp Clin Cancer Res 2008, 27:22. 2494538 18644116 10.1186/1756-9966-27-22
-
(2008)
J Exp Clin Cancer Res
, vol.27
, pp. 22
-
-
Puca, R.1
Nardinocchi, L.2
D'Orazi, G.3
-
11
-
-
0142166332
-
Involvement of hypoxia-inducible factor 1 in human cancer
-
10.1038/nrc1187
-
Semenza GL Involvement of hypoxia-inducible factor 1 in human cancer Nature Rev Cancer 2003, 3:721-732. 10.1038/nrc1187
-
(2003)
Nature Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
12
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
41725 7539918 10.1073/pnas.92.12.5510
-
Wang GL Jiang B-H Rue EA Semenza GL Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc Natl Acad Sci USA 1995, 92:5510-5514. 41725 7539918 10.1073/ pnas.92.12.5510
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.-H.2
Rue, E.A.3
Semenza, G.L.4
-
13
-
-
0029859510
-
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
-
8897823
-
Jiang BH Semenza GL Bauer H Marti H Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension Am J Physiol 1996, 271:C1172-C1180. 8897823
-
(1996)
Am J Physiol
, vol.271
-
-
Jiang, B.H.1
Semenza, G.L.2
Bauer, H.3
Marti, H.4
-
14
-
-
36949000697
-
Hypoxia-inducible factor-1a contributes to hypoxia-induced chemoresistance in gastric cancer
-
17953712
-
Liu L Ning X Sun L Zhang H Shi Y Guo C Han S Liu J Sun S Han Z Wu K Fan D Hypoxia-inducible factor-1a contributes to hypoxia-induced chemoresistance in gastric cancer Cancer Sci 2008, 99:121-128. 17953712
-
(2008)
Cancer Sci
, vol.99
, pp. 121-128
-
-
Liu, L.1
Ning, X.2
Sun, L.3
Zhang, H.4
Shi, Y.5
Guo, C.6
Han, S.7
Liu, J.8
Sun, S.9
Han, Z.10
Wu, K.11
Fan, D.12
-
15
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
-
10.1074/jbc.271.50.32253 8943284
-
Huang LE Arany Z Livingston DM Bunn HF Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit J Biol Chem 1996, 271:32253-32259. 10.1074/jbc.271.50.32253 8943284
-
(1996)
J Biol Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
16
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
46495 8387214 10.1073/pnas.90.9.4304
-
Wang GL Semenza GL General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia Proc Natl Acad Sci USA 1993, 90:4304-4308. 46495 8387214 10.1073/pnas.90.9.4304
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
17
-
-
48349098840
-
Resistance to chemotherapy: New treatments and novel insights
-
10.1038/sj.bjc.6604510 18665178
-
Raguz S Yague E Resistance to chemotherapy: New treatments and novel insights Br J Cancer 2008, 99:387-391. 10.1038/sj.bjc.6604510 18665178
-
(2008)
Br J Cancer
, vol.99
, pp. 387-391
-
-
Raguz, S.1
Yague, E.2
-
18
-
-
4944246547
-
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
-
1770458 15452150 10.1136/jcp.2003.015032
-
Greijer AE Wall van der E The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis J Clin Pathol 2004, 57:1009-1014. 1770458 15452150 10.1136/jcp.2003.015032
-
(2004)
J Clin Pathol
, vol.57
, pp. 1009-1014
-
-
Greijer, A.E.1
Wall, E.2
-
20
-
-
0030561363
-
The P-glicoprotein multidrug transporter
-
9304397
-
Fardel O Lecureur V Guillouzo A The P-glicoprotein multidrug transporter Gen Pharmacol 1996, 27:1283-1291. 9304397
-
(1996)
Gen Pharmacol
, vol.27
, pp. 1283-1291
-
-
Fardel, O.1
Lecureur, V.2
Guillouzo, A.3
-
22
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
1850121 10934146
-
Talks KL Turley H Gatter KC Maxwell PH Pugh CW Ratcliff PJ Harris AL The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages Am J Pathol 2000, 157:411-421. 1850121 10934146
-
(2000)
Am J Pathol
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliff, P.J.6
Harris, A.L.7
-
23
-
-
0142258245
-
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP
-
10.1016/S0092-8674(03)00802-X 14567915
-
Zhang Q Yoshimatsu Y Hildebrabd J Frisch SM Goodman RH Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP Cell 2003, 115:177-186. 10.1016/ S0092-8674(03)00802-X 14567915
-
(2003)
Cell
, vol.115
, pp. 177-186
-
-
Zhang, Q.1
Yoshimatsu, Y.2
Hildebrabd, J.3
Frisch, S.M.4
Goodman, R.H.5
-
24
-
-
0345734277
-
HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells
-
Hofmann TG Stollberg N Schmitz ML Will H HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells Cancer Res 2003, 63:8781-8787
-
(2003)
Cancer Res
, vol.63
, pp. 8781-8787
-
-
Hofmann, T.G.1
Stollberg, N.2
Schmitz, M.L.3
Will, H.4
-
25
-
-
4644342576
-
Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons
-
10.1016/j.cub.2004.09.050 15458648
-
Doxakis E Huang EJ Davies AM Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons Curr Biol 2004, 14:1761-1765. 10.1016/j.cub.2004.09.050 15458648
-
(2004)
Curr Biol
, vol.14
, pp. 1761-1765
-
-
Doxakis, E.1
Huang, E.J.2
Davies, A.M.3
-
26
-
-
0038282482
-
The hypoxia-inducible factor-1α is a negative factor for tumor therapy
-
10.1038/sj.onc.1206385 12761491
-
Unruh A Ressel A Mohamed HG Johnson RS Nadrowitz R Richter E Katschinski DM Wenger RH The hypoxia-inducible factor-1α is a negative factor for tumor therapy Oncogene 2003, 22:3213-3220. 10.1038/sj.onc.1206385 12761491
-
(2003)
Oncogene
, vol.22
, pp. 3213-3220
-
-
Unruh, A.1
Ressel, A.2
Mohamed, H.G.3
Johnson, R.S.4
Nadrowitz, R.5
Richter, E.6
Katschinski, D.M.7
Wenger, R.H.8
-
28
-
-
26844462296
-
HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations
-
10.1016/j.febslet.2005.09.008 16212962
-
Di Stefano V Mattiussi M Sacchi A D'Orazi G HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations FEBS Lett 2005, 579:5473-5480. 10.1016/j.febslet.2005.09.008 16212962
-
(2005)
FEBS Lett
, vol.579
, pp. 5473-5480
-
-
Di Stefano, V.1
Mattiussi, M.2
Sacchi, A.3
D'Orazi, G.4
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