-
1
-
-
37249061592
-
What makes tumors multidrug resistant?
-
Borst P., Jonkers J., and Rottenberg S. What makes tumors multidrug resistant?. Cell Cycle 6 (2007) 2782-2787
-
(2007)
Cell Cycle
, vol.6
, pp. 2782-2787
-
-
Borst, P.1
Jonkers, J.2
Rottenberg, S.3
-
2
-
-
0242610903
-
p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells
-
Fraser M., Leung B.M., Yan X., Dan H.C., Cheng J.Q., and Tsang B.K. p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells. Cancer Res 63 (2003) 7081-7088
-
(2003)
Cancer Res
, vol.63
, pp. 7081-7088
-
-
Fraser, M.1
Leung, B.M.2
Yan, X.3
Dan, H.C.4
Cheng, J.Q.5
Tsang, B.K.6
-
3
-
-
0345256652
-
Cisplatin: mode of cytotoxic action and molecular basis of resistance
-
Siddik Z.H. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22 (2003) 7265-7279
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
5
-
-
0037737758
-
Regulation of p53 responses by post-translational modifications
-
Xu Y. Regulation of p53 responses by post-translational modifications. Cell Death Differ 10 (2003) 400-403
-
(2003)
Cell Death Differ
, vol.10
, pp. 400-403
-
-
Xu, Y.1
-
6
-
-
0037377060
-
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
-
Brooks C.L., and Gu W. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol 2 (2003) 164-171
-
(2003)
Curr Opin Cell Biol
, vol.2
, pp. 164-171
-
-
Brooks, C.L.1
Gu, W.2
-
7
-
-
0032192140
-
The complexity of p53 modulation: emerging patterns from divergent signals
-
Giaccia A.J., and Kastan M.B. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 12 (1998) 2973-2983
-
(1998)
Genes Dev
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
8
-
-
0345898928
-
Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
-
Kim Y.H., Choi C.Y., Lee S., Conti M.A., and Kim Y. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J Biol Chem 273 (1998) 875-879
-
(1998)
J Biol Chem
, vol.273
, pp. 875-879
-
-
Kim, Y.H.1
Choi, C.Y.2
Lee, S.3
Conti, M.A.4
Kim, Y.5
-
9
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser46 and mediates apoptosis
-
D'Orazi G., Cecchinelli B., Bruno T., Manni I., Higashimoto Y., Saito S., et al. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser46 and mediates apoptosis. Nat. Cell Biol 4 (2002) 11-19
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
Saito, S.6
-
10
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
Hofmann T.G., Moller A., Sirma H., Zentgraf H., Taya Y., Droge W., et al. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat. Cell Biol 4 (2002) 1-10
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
Droge, W.6
-
11
-
-
0345830383
-
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis
-
Di Stefano V., Rinaldo C., Sacchi A., Soddu S., and D'Orazi G. Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis. Exp Cell Res 293 (2004) 311-320
-
(2004)
Exp Cell Res
, vol.293
, pp. 311-320
-
-
Di Stefano, V.1
Rinaldo, C.2
Sacchi, A.3
Soddu, S.4
D'Orazi, G.5
-
12
-
-
33847045212
-
Roscovitine-activated HIP2 kinase induces phosphorylation of wtp53 at Ser-46 in human MCF-7 breast cancer cells
-
Wesierska-Gadek J., Schmitz M.L., and Ranftler C. Roscovitine-activated HIP2 kinase induces phosphorylation of wtp53 at Ser-46 in human MCF-7 breast cancer cells. J Cell Biochem 100 (2007) 865-874
-
(2007)
J Cell Biochem
, vol.100
, pp. 865-874
-
-
Wesierska-Gadek, J.1
Schmitz, M.L.2
Ranftler, C.3
-
13
-
-
33947273628
-
Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM
-
Dauth I., Kruger J., and Hofmann T.G. Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM. Cancer Res 67 (2007) 2274-2279
-
(2007)
Cancer Res
, vol.67
, pp. 2274-2279
-
-
Dauth, I.1
Kruger, J.2
Hofmann, T.G.3
-
14
-
-
41949130508
-
Ubiquitination and degradation of homeodomain-interacting protein kinase 2 (HIPK2) by WD40-repeat/SOCS box protein WSB-1
-
10.1074/jbc.M708873200
-
Choi D.W., Seo Y.-M., Kim E.-A., Sung K.S., Ahn J.W., Park S.-J., et al. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 (HIPK2) by WD40-repeat/SOCS box protein WSB-1. J Biol Chem (2007) 10.1074/jbc.M708873200
-
(2007)
J Biol Chem
-
-
Choi, D.W.1
Seo, Y.-M.2
Kim, E.-A.3
Sung, K.S.4
Ahn, J.W.5
Park, S.-J.6
-
15
-
-
34548754566
-
HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8-extrinsic apoptotic pathway
-
10.1038/sj.cdd.4402186
-
Pistritto G., Puca R., Nardinocchi L., Sacchi A., and D'Orazi G. HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8-extrinsic apoptotic pathway. Cell Death Differ (2007) 10.1038/sj.cdd.4402186
-
(2007)
Cell Death Differ
-
-
Pistritto, G.1
Puca, R.2
Nardinocchi, L.3
Sacchi, A.4
D'Orazi, G.5
-
16
-
-
33646589651
-
Autoregulatory control of the p53 response by caspases-mediated processing of HIPK2
-
Gresko E., Roscic A., Vichalkovski S., del Sal G., and Schmitz M.L. Autoregulatory control of the p53 response by caspases-mediated processing of HIPK2. EMBO J 25 (2006) 1883-1894
-
(2006)
EMBO J
, vol.25
, pp. 1883-1894
-
-
Gresko, E.1
Roscic, A.2
Vichalkovski, S.3
del Sal, G.4
Schmitz, M.L.5
-
17
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops. Oncogene 24 (2005) 2899-2908
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
18
-
-
0023875417
-
cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells
-
Andrews P.A., Velury S., Mann S.C., and Howell S.B. cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. Cancer Res 48 (1998) 68-73
-
(1998)
Cancer Res
, vol.48
, pp. 68-73
-
-
Andrews, P.A.1
Velury, S.2
Mann, S.C.3
Howell, S.B.4
-
19
-
-
0031060238
-
DNA damage inducible-gene expression following platinum treatment in human ovarian carcinoma cell lines
-
Delmastro D.A., Li J., Vaisman A., Solle M., and Chaney S.G. DNA damage inducible-gene expression following platinum treatment in human ovarian carcinoma cell lines. Cancer Chemother Pharmacol 39 (1997) 245-253
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 245-253
-
-
Delmastro, D.A.1
Li, J.2
Vaisman, A.3
Solle, M.4
Chaney, S.G.5
-
20
-
-
0034664733
-
P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda K., Arakawa H., Tanaka T., Matsuda K., Tanikawa C., Mori T., et al. P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102 (2000) 849-862
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
-
21
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen C., and Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7 (1987) 2754-2756
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2754-2756
-
-
Chen, C.1
Okayama, H.2
-
22
-
-
33745987641
-
Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner
-
Yan X., Fraser M., Qiu Q., and Tsang B.K. Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner. Gynecol Oncol 102 (2006) 348-355
-
(2006)
Gynecol Oncol
, vol.102
, pp. 348-355
-
-
Yan, X.1
Fraser, M.2
Qiu, Q.3
Tsang, B.K.4
-
23
-
-
33847398755
-
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
-
Pierantoni G.M., Rinaldo C., Mottolese M., Di Benedetto A., Esposito F., Soddu S., and Fusco A. High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2. J Clin Invest 117 (2007) 693-702
-
(2007)
J Clin Invest
, vol.117
, pp. 693-702
-
-
Pierantoni, G.M.1
Rinaldo, C.2
Mottolese, M.3
Di Benedetto, A.4
Esposito, F.5
Soddu, S.6
Fusco, A.7
-
25
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis
-
Greenblatt M.S., Bennet W.P., Hollstein M., and Harris C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54 (1994) 4855-4878
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennet, W.P.2
Hollstein, M.3
Harris, C.C.4
-
26
-
-
0033376873
-
New approaches to understanding p53 gene tumor mutation spectra
-
Hollstein M., Hergenhahn M., Yang Q., Bartsch H., Wang Z.Q., and Hainaut P. New approaches to understanding p53 gene tumor mutation spectra. Mutat Res 432 (1999) 199-209
-
(1999)
Mutat Res
, vol.432
, pp. 199-209
-
-
Hollstein, M.1
Hergenhahn, M.2
Yang, Q.3
Bartsch, H.4
Wang, Z.Q.5
Hainaut, P.6
-
27
-
-
11844293427
-
P53 and prognosis: new insights and further complexity
-
Vousden K.H., and Prives C. P53 and prognosis: new insights and further complexity. Cell 120 (2005) 7-10
-
(2005)
Cell
, vol.120
, pp. 7-10
-
-
Vousden, K.H.1
Prives, C.2
-
28
-
-
22544433198
-
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified
-
Mayo L.D., Rok Seo Y., Jackson M.W., Smith M.L., Rivera Guzman J.R., Koegaonkar C.K., et al. Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified. J Biol Chem 280 (2005) 25953-25959
-
(2005)
J Biol Chem
, vol.280
, pp. 25953-25959
-
-
Mayo, L.D.1
Rok Seo, Y.2
Jackson, M.W.3
Smith, M.L.4
Rivera Guzman, J.R.5
Koegaonkar, C.K.6
-
29
-
-
33644535515
-
Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells
-
Ichwan S.J.A., Yamada S., Sumreijkanchanakij P., Ibrahim-Auerkari E., Eto K., and Ikeda M.A. Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. Oncogene 25 (2006) 1216-1224
-
(2006)
Oncogene
, vol.25
, pp. 1216-1224
-
-
Ichwan, S.J.A.1
Yamada, S.2
Sumreijkanchanakij, P.3
Ibrahim-Auerkari, E.4
Eto, K.5
Ikeda, M.A.6
-
30
-
-
1142299526
-
Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors
-
Yoshida K., Monden M., Nakamura Y., and Arakawa H. Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors. Cancer Sci 95 (2004) 91-97
-
(2004)
Cancer Sci
, vol.95
, pp. 91-97
-
-
Yoshida, K.1
Monden, M.2
Nakamura, Y.3
Arakawa, H.4
-
31
-
-
33745967055
-
Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis
-
Nakamura Y., Futamura M., Kamino H., Yoshida K., Nakamura Y., and Arakawa H. Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis. Cancer Sci 97 (2006) 633-641
-
(2006)
Cancer Sci
, vol.97
, pp. 633-641
-
-
Nakamura, Y.1
Futamura, M.2
Kamino, H.3
Yoshida, K.4
Nakamura, Y.5
Arakawa, H.6
|