Direct CNS delivery of siRNA mediates robust silencing in oligodendrocytes

Oligonucleotides

Volumn 19, Issue 1, 2009, Pages 23-29

  Querbes, William ^a   Ge, Pei ^a   Zhang, Wenjun ^a   Fan, Yupeng ^a   Costigan, Jason ^a   Charisse, Klaus ^a   Maier, Martin ^a   Nechev, Lubomir ^a   Manoharan, Muthiah ^a   Kotelianski, Victor ^a   Sah, Dinah W Y ^a  

^a ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; SMALL INTERFERING 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; GENE SILENCING; INFUSION RATE; MALE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; RNA INTERFERENCE;

ANIMALS; BASE SEQUENCE; CENTRAL NERVOUS SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING;

PRIMATES;

EID: 61349120741     PISSN: 15454576     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.2008.0165     Document Type: Article

References (25)

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