The importance of discerning shape in molecular pharmacology

Trends in Pharmacological Sciences

Volumn 30, Issue 3, 2009, Pages 138-147

  Kortagere, Sandhya ^a   Krasowski, Matthew D ^b   Ekins, Sean ^c,d  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; BENZODIAZEPINE DERIVATIVE; CLOMIPRAMINE; DESIPRAMINE; DOPAMINE 4 RECEPTOR; IBUPROFEN; LIGAND; PROMETHAZINE; PROTEIN TYROSINE PHOSPHATASE SHP 2; QUETIAPINE; SECOBARBITAL;

ANTIGEN ANTIBODY COMPLEX; COMPUTER MODEL; DRUG RESEARCH; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR RECOGNITION; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW;

ALGORITHMS; ANTIGEN-ANTIBODY REACTIONS; BINDING SITES; DRUG DESIGN; DRUG DISCOVERY; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHARMACOLOGY; PROTEIN BINDING; PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SIGNAL TRANSDUCTION;

EID: 61349117968     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2008.12.001     Document Type: Review

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