Shape Signatures: A New Approach to Computer-Aided Ligand- and Receptor-Based Drug Design

Journal of Medicinal Chemistry

Volumn 46, Issue 26, 2003, Pages 5674-5690

  Zauhar, Randy J ^a   Moyna, Guillermo ^a   Tian, LiFeng ^a   Li, ZhiJian ^a   Welsh, William J ^b  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG RECEPTOR; INDINAVIR; PROTEINASE INHIBITOR;

ARTICLE; COMPUTER AIDED DESIGN; DRUG BINDING SITE; DRUG DESIGN; DRUG DETERMINATION; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; GEOMETRY; HISTOGRAM; HUMAN IMMUNODEFICIENCY VIRUS; LIPOPHILICITY; NONHUMAN;

BINDING SITES; DATABASES, FACTUAL; DRUG DESIGN; HIV PROTEASE INHIBITORS; INDINAVIR; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; THERMODYNAMICS;

EID: 0345735309     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030242k     Document Type: Article

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